CFP Proteins

Protein Summary

This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alternative names and synonyms associated with CFP

• complement factor properdin (CFP) antibody
• complement factor properdin (Cfp) antibody

• BCFG antibody
• BFD antibody
• Pfc antibody
• PFD antibody
• Properdin antibody

Protein level used designations for Complement Factor P Proteins (CFP)

complement factor P , properdin , properdin P factor, complement , properdin factor, complement , Properdin P factor, complement