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Browse our anti-Solute Carrier Family 13 Member 3 (SLC13A3) Antibodies

Full name:: anti-Solute Carrier Family 13 Member 3 Antibodies (SLC13A3)

On www.antibodies-online.com are 27 Solute Carrier Family 13 Member 3 (SLC13A3) Antibodies from 9 different suppliers available. Additionally we are shipping Solute Carrier Family 13 Member 3 Proteins (4) and many more products for this protein. A total of 39 Solute Carrier Family 13 Member 3 products are currently listed.

Synonyms:: MGC108337, NaDC-3, Nadc3, SDCT2, SLC13A3, zgc:77173

list all antibodies	Gene Name	GeneID	UniProt
	SLC13A3	64849	Q8WWT9
	SLC13A3	114644	Q91Y63
	SLC13A3	64846
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Most Popular Reactivities for anti-Solute Carrier Family 13 Member 3 (SLC13A3) Antibodies

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anti-Human Antibodies:

anti-Mouse (Murine) Antibodies:

9 WB Antibodies

anti-Rat (Rattus) Antibodies:

9 WB Antibodies

All available anti-Solute Carrier Family 13 Member 3 Antibodies

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Relevant Pathways for anti-Solute Carrier Family 13 Member 3 Antibodies

Dicarboxylic Acid Transport

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More Antibodies against Solute Carrier Family 13 Member 3 Interaction Partners

Human Solute Carrier Family 13 Member 3 (SLC13A3) interaction partners

NaDC3-related immunostaining was detected in the basolateral membrane of proximal tubules and in the basolateral membrane and/or luminal membrane of principal cells in connecting segments and collecting ducts
OAT1 and NaDC3 in the basolateral membrane and OAT4 in the luminal membrane of proximal tubule cells are responsible for the avid renal secretion of N-carbamoylglutamate.
In a study addressing genetic, social, and environmental contributors of chronic kidney disease with tubulointerstitial damages in Sri Lanka, SNP rs6066043 of SLC13A3 was found attributable risk of 50%.
study concludes NaDC3 present at the basolateral membrane of proximal tubule cells mediates sodium-dependent glutathione (GSH) uptake; the kinetic data show that NaDC3 is a low-affinity GSH transporter
The data 1) reveal alpha-ketoglutarate as a common high-affinity substrate of NaDC3, OAT1, and OAT3
The results indicate that SLC13A3 is a direct downstream target of PITX2 transcriptional regulation and that levels of PITX2 and SLC13A3 modulate responses to oxidative stress in ocular cells.
NaDC3 promotes cellular senescence probably by inhibiting NAD(+)-dependent SIRT1.
The narrow substrate specificity prevents interaction of drugs with dicarboxylate-like structure with hNaDC-3 and ensures sufficient support of the proximal tubule cells with alpha-ketoglutarate for anion secretion via organic anion transporter 1 or 3.
We provide direct evidence of the localization of NaDC3 at the basolateral membrane of human renal proximal tubule cells and identify a di-hydrophobic amino acid motif VW as basolateral localization signal in the N-terminal cytoplasmic domain of NaDC3.

Mouse (Murine) Solute Carrier Family 13 Member 3 (SLC13A3) interaction partners

demonstrate the membrane translocation of 3OH-GA mediated by NaDC3 and the cis-inhibitory effect on OCT2-mediated transport of cations

Solute Carrier Family 13 Member 3 (SLC13A3) Antigen Profile

Antigen Summary

Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.

Alternative names and synonyms associated with Solute Carrier Family 13 Member 3 (SLC13A3)

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (slc13a3) antibody
solute carrier family 13 member 3 (SLC13A3) antibody
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 L homeolog (slc13a3.L) antibody
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (Slc13a3) antibody
solute carrier family 13 member 3 (Slc13a3) antibody

MGC108337 antibody
NaDC-3 antibody
Nadc3 antibody
SDCT2 antibody
SLC13A3 antibody
zgc:77173 antibody

Protein level used designations for SLC13A3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 , solute carrier family 13 member 3 , Na(+)/dicarboxylate cotransporter 3 , hNaDC3 , naDC-3 , sodium-dependent high affinity dicarboxylate transporter 3 , sodium-dependent high-affinity dicarboxylate transporter 2 , mNaDC3 , rNaDC3 , sodium-dependent high-affinity dicarboxylate transporter 3

GENE ID	SPECIES
548493	Xenopus (Silurana) tropicalis
100029726	Monodelphis domestica
100071226	Equus caballus
458302	Pan troglodytes
405838	Danio rerio
444773	Xenopus laevis
770495	Gallus gallus
64849	Homo sapiens
485910	Canis lupus familiaris
526291	Bos taurus
114644	Mus musculus
64846	Rattus norvegicus

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