SLC13A3 antibody (Middle Region)

Catalog No. ABIN2776815

The Rabbit Polyclonal anti-SLC13A3 antibody (ABIN2776815) specifically detects SLC13A3 in WB and IHC. The antibody is reactive with Human, Rat, Mouse, Dog, Rabbit, Cow, Horse, Zebrafish (Danio rerio) and Pig samples.

Quick Overview for SLC13A3 antibody (Middle Region) (ABIN2776815)

Target: SLC13A3 (Solute Carrier Family 13 Member 3 (SLC13A3))

Reactivity: Human, Rat, Mouse, Dog, Rabbit, Cow, Horse, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC13A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SLC13A3 Antibody

Binding Specificity: Middle Region

Purpose: SLC13A3 Antibody - middle region

Sequence: GLSFRGWRKN KSEIRTNAED RARAVIREEY QNLGPIKFAE QAVFILFCMF

Predicted Reactivity: Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 85%, Rabbit: 93%, Rat: 92%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against SLC13A3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC13A3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112059

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC13A3

Target: SLC13A3 (Solute Carrier Family 13 Member 3 (SLC13A3))

Alternative Name: SLC13A3

Background:

Background Information: Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. SLC13A3 represents the high-affinity form.Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.

Gene Name: Solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

Alternative Symbols: NADC3, SDCT2, ARLIAK

Protein Name: Solute carrier family 13 member 3

Molecular Weight: 61kDa

Gene ID: 64849

NCBI Accession: NP_001011554

UniProt: Q8WWT9

Pathways: Dicarboxylic Acid Transport