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Human Polyclonal SLC7A1 Primary Antibody for IHC, IHC (p) - ABIN4288211
Li, Wu, Shah, Chen, Wangpaichitr, Kuo, Feun, Han, Suarez, Prince, Savaraj: Degradation of AMPK-α1 sensitizes BRAF inhibitor-resistant melanoma cells to arginine deprivation. in Molecular oncology 1970
Cow (Bovine) Polyclonal SLC7A1 Primary Antibody for WB - ABIN2781583
Kaneko, Okuda-Ashitaka, Ando, Nishimura, Igarashi, Maeda, Furuta, Suzuki, Matsumura, Ito: Polyamines upregulate the mRNA expression of cationic amino acid transporter-1 in human retinal pigment epithelial cells. in American journal of physiology. Cell physiology 2007
Estradiol increases arginine transport and CAT-1 activity through modulation of constitutive signaling transduction pathways involving ERK. Progesterone inhibits arginine transport and CAT-1 via both PKCalpha and ERK1/2 phosphorylation.
The rs41318021 polymorphism in the SLC7A1 gene was not associated with essential hypertension in 50-year-old subjects.
Overexpression of arginine transporter CAT-1 (show CRAT Antibodies) is associated with accumulation of L-arginine (show GATM Antibodies) and cell growth in human colorectal cancer tissue.
CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution.
mRNA levels for high-affini (show CRAT Antibodies)ty CAT-1, expressed as a percentage of the wild-type value, are increased by an average 12% an (show DMD Antibodies)d 32% in mdx and transgenic mdx:utr mice respectively.
The data demonstrates that CAT1 (show CRAT Antibodies) significantly (but most likely not exclusively) contributes to the cellular uptake of asymmetric dimethylarginine.
In hypoxic human pulmonary microvascular endothelial cells, overexpression of CAT-1 (show CRAT Antibodies) resulted in significantly greater L-arginine (show GATM Antibodies) transport and NO production
In acute congestive heart failure acute renal impairment function and the modulation of metabolism and extracellular transport by the DDAH-1 (show DDAH1 Antibodies)/CAT-1 (show CRAT Antibodies) system determine high ADMA and SDMA levels after therapy for acute congestive heart failure.
Insulin (show INS Antibodies) increased hCATs-L-arginine (show GATM Antibodies) transport, maximal transport capacity, and hCAT-1 expression. Sp1 (show PSG1 Antibodies) nuclear protein (show RDBP Antibodies) abundance and binding to DNA, and SLC7A1 promoter activity was increased by insulin (show INS Antibodies).
Data show that the CAT-1 (show CRAT Antibodies) isoform plays a role in arginine uptake.
A time-dependent decrease in serum and tissue ADMA and increase in mRNA expression of DDAH-1 and PRMT-1 as well as higher rates of mRNA expression of CAT-1 and lower rates of CAT-2A and CAT-2B were found after 8-week MCD diet.
Endothelial CAT-1 overexpression can counter the ability of oxidative stress.
L-argine transporters CAT-1 and CAT-2A expression and function are significantly increased in Duchenne muscular dystrophy (show DMD Antibodies) mice.
findings suggest a novel role for GRB2 (show GRB2 Antibodies) in ecotropic MLV entry and infection by facilitating mCAT-1 trafficking
data suggest that direct interaction of eNOS (show NOS3 Antibodies) with CAT-1 enhances NO release by a mechanism not involving arginine transport.
Ecotropic MuLV and its env protein downregulate the MuLV receptor (CAT1) via interaction of CAT1 with clathrin adaptor protein complexes.
Ecotropic mouse gammaretroviruses entry and virus-induced syncytium formation using the CAT-1 receptor are mediated by a small number of critical amino acid residues in receptor and virus Env (show ERVW-1 Antibodies).
analysis of how a bifunctional intronic element regulates the expression of the arginine/lysine transporter Cat-1 via mechanisms involving the purine-rich element binding protein A (Pur alpha (show PURA Antibodies))
High performance liquid chromatography (HPLC) analyses showed that Transmissible gastroenteritis virus infection leads to reduced arginine uptake at 48 hours post-infection (hpi). Expression of cationic amino acid transporter 1 (CAT-1) was attenuated as well.
Arginine supplementation enhances small intestinal expression of SLC7A7 (show Slc7a7 Antibodies) and SLC7A1.
Changes in the expression of b(0,+) and CAT-1 in pigs fed on amino acid supplemented versus high proteins diets.
Data show that in minipigs, increased weight and cholesterol resulting from a high-cholesterol diet are correlated with a decrease in the expression of miRNA-122, and that gene expression levels of CAT1 do not differ between groups.
Radiation hybrid mapping data indicate that the porcine SLC7A1 maps to the distal end of the short arm of pig chromosome 11
Lipopolysaccharide/tumor necrosis factor-alpha (show TNF Antibodies) treatment increased the expression of iNOS (show NOS2 Antibodies), arginase II (show ARG2 Antibodies), CAT-1, and CAT-2 (show SLC7A2 Antibodies) mRNA.
acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor\; plays a role in the Na+-independent y+ cationic amino acid transport system
, amino acid transporter, cationic 1
, ecotropic retroviral leukemia receptor homolog
, ecotropic retroviral receptor
, ecotropic retrovirus receptor homolog
, high affinity cationic amino acid transporter 1
, solute carrier family 7 member 1
, system Y+ basic amino acid transporter
, cationic amino acid transporter 1
, ecotropic retroviral leukemia receptor
, ecotropic retrovirus receptor
, Solute carrier family 7 member A1 (amino acid transporter cationic 1)
, cationic amino acid transporter, y+ system
, cationinc amino acid transporter 1
, solute carrier family 7, member 1
, solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
, cationic amino acid transporter-1
, high affinity cationic amino acid transporter 1-like