anti-Calcium Modulating Ligand Antibodies

Protein Summary

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

Alternative names and synonyms associated with Calcium Modulating Ligand (CAMLG)

• calcium modulating ligand L homeolog (camlg.L) antibody
• calcium modulating ligand (CAMLG) antibody
• calcium modulating ligand (camlg) antibody
• calcium modulating ligand (Caml) antibody
• calcium modulating ligand (Camlg) antibody

• AI385748 antibody
• Caml antibody
• Camlg antibody
• MGC53900 antibody

Protein level used designations for CAMLG

calcium modulating ligand , calcium signal-modulating cyclophilin ligand , calcium modulating cyclophilin ligand CAML , calcium-modulating cyclophilin ligand , calcium-signal modulating cyclophilin ligand , cyclophilin B-binding protein