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Human Polyclonal VIL1 Primary Antibody for IHC, IHC (p) - ABIN4365288
Kiflemariam, Andersson, Asplund, Pontén, Sjöblom: Scalable in situ hybridization on tissue arrays for validation of novel cancer and tissue-specific biomarkers. in PLoS ONE 2012
Human Polyclonal VIL1 Primary Antibody for IHC, IHC (p) - ABIN4365289
Andersson, Konrad, Ashok, Pontén, Hober, Asplund: Antibodies biotinylated using a synthetic Z-domain from protein A provide stringent in situ protein detection. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2013
Data show that data demonstrate that tumor protein translationally-controlled 1 (TCTP) overexpression has a promotion effect on caudal type homeo box transcription factor 2 protein (CDX2) and villin1 protein (VIL1) expression.
Villin, Pro-Ex-C and progesterone/estrogen receptor expression have diagnostic and predictive roles in endocervical and endometrioid adenocarcinoma.
Induction of cell stress alters the actin cytoskeleton in intestinal epithelial cells via changes in the actin-binding proteins villin-1 and gelsolin.
Villin 1 is released in plasma during acute kidney injury and shows potential as an early marker for proximal tubular injury/necrosis.
Villin has a higher positive expression in Primary Pulmonary Enteric Adenocarcinoma cases. Villin proved to be a very sensitive and helpful enteric marker in the differential diagnosis between PEAC and other lung adenocarcinomas.
villin directly interacts with a transcriptional corepressor and ligand of the Slug promoter, ZBRK1.
Data indicate an association between highly fucosylated glycans and caudal type homeobox 1 (CDX1) and/or villin mRNA expression that both correlate with cell differentiation.
study demonstrates that G. duodenalis-mediated disruption of villin is, at least, in part dependent on activation of myosin light chain kinase
Thus, villin plays an important role in establishing the balance between actin polymerization and actin severing to facilitate the initial steps of Salmonella entry.
Collective expression pattern of tensin/profilin-1/villin-1/talin could be a biomarker to estimate the prognosis of esophageal squamous cell carcinoma patients.
harmonin and villin autoantibodies are sensitive and specific markers of IPEX, differentiate IPEX, including atypical cases, from other early childhood disorders associated with enteropathy
villin immunohistochemistry is a reliable and superior adjunct in the diagnosis of microvillus inclusion disease
Discriminated small-cell lung carcinoma from large-cell neuroendocrine lung carcinoma with immunohistochemical markers BAI3, CDX2 and VIL1.
We demonstrated that the VIL1 gene is a potential candidate molecular marker for high serum AFP-associated HCC and a predictive candidate for the postoperative recurrence and poorer prognosis of HCC.
study confirmed finding of VIL1 as a diagnostic marker of cervical adenocarcinoma
identified villin, an actin-binding protein, as the 95 kDa antigen in four of five sera from patients with IPEX syndrome
identified VIL1 as a novel biomarker of cervical adenocarcinoma
villin has calcium-sensitive actin-capping and actin-depolymerizing sites
tyrosine phosphorylation at residues 60, 81, and 256 of human villin plays an essential role in cell migration as well as in the reorganization of the actin cytoskeleton
H. pylori induction of villin in the stomach correlates with activation and cooperative binding of Elk-1 and the SRF to the proximal promoter of villin
This study also highlights the potential role of villin's pro-apoptotic function in the pathogenesis of inflammatory bowel disease, ischemia-reperfusion injury, enteroinvasive bacterial and parasitic infections.
Competition between tryptophan fluorescence and electron transfer during unfolding of the villin headpiece.
villin severs F-actin to ensure microvillus depolarization and enterocyte remodeling upon intestinal injury
Villin-Cre(+);Klf4(fl/fl) have greater susceptibility to chemical-induced gastric carcinogenesis and increased rates of gastric tumor progression than control mice.
The data establish that meprins interact with and cleave villin and actin, and these cytoskeletal proteins are substrates for meprins.
a lack of villin does not significantly alter basal and secretagogue-stimulated electrolyte movements across the epithelium of the mouse jejunum in vivo
These results indicate that an important patterning event involving villin expression occurs in the gut epithelium at 16 days, which may define the epithelial boundary between stomach and intestine.
different regulatory sequences of the villin gene regulate expression in the intestinal epithelium
Data show that villin, characteristic markers of brush borders, become abnormally distributed along these atypical basolateral membranes in gal3(-/-) mice.
Villin is an actin regulatory protein that organizes, integrates and regulates multiple epithelial cell functions.
This gene encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed\; they result from utilization of alternate poly-adenylation signals present in the terminal exon.
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