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Full name:: Transcription Factor 15 (Basic Helix-Loop-Helix) Proteins (TCF15)

On www.antibodies-online.com are 3 Transcription Factor 15 (Basic Helix-Loop-Helix) (TCF15) Proteins from 2 different suppliers available. Additionally we are shipping TCF15 Antibodies (28) and many more products for this protein. A total of 33 TCF15 products are currently listed.

Synonyms:: bHLH-EC2, bHLHa40, BHLHEC2, EC2, meso1, par1, Paraxis, TCF-15

list all proteins	Gene Name	GeneID	UniProt
	TCF15	6939	Q12870
	TCF15	21407	Q60756
Rat TCF15	TCF15	296272
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Human Transcription Factor 15 (Basic Helix-Loop-Helix) (TCF15) interaction partners

Genetic variation in MEOX2 (show MEOX2 Proteins), but not TCF15, is a strong predictor of CHD (show CHDH Proteins). Further experimental studies should elucidate the underlying molecular mechanisms.
Microarray profiling on freshly isolated ECs had a genetic signature for microvascular heart ECs and identified Meox (show MEOX2 Proteins)2/Tcf15 heterodimers as novel transcriptional determinants. This signature was similar in skeletal muscle and adipose tissue endothelium.
Activation of TGFbeta (show TGFB1 Proteins) recruits p300 (show EP300 Proteins) to the KLF5 (show KLF5 Proteins)-Smad (show SMAD1 Proteins) complex to acetylate KLF5 (show KLF5 Proteins), and the complex with acetylated KLF5 (show KLF5 Proteins) binds to the Smad (show SMAD1 Proteins) binding element and alters the binding of other factors to p15 (show CDKN2B Proteins) promoter to induce its transcription

Mouse (Murine) Transcription Factor 15 (Basic Helix-Loop-Helix) (TCF15) interaction partners

Micrarray profiling on freshly isolated ECs had a genetic signature for microvascular heart ECs and identified Meox2 (show MEOX2 Proteins)/Tcf15 heterodimers as novel transcriptional determinants. This signature was similar in skeletal muscle and adipose tissue endothelium.
The data demonstrate that PARAXIS initiates and stabilizes somite epithelialization by integrating signals from multiple pathways to control the reorganization of the ECM (show MMRN1 Proteins), cytoskeleton, and adhesion junctions during MET.
Tcf15 contributes toward steering pluripotent cells in the direction of somatic lineages and that it will serve as a valuable tool for monitoring and interrogating early developmental transitions.

Xenopus laevis Transcription Factor 15 (Basic Helix-Loop-Helix) (TCF15) interaction partners

The molecular characterization of paraxis is reported inh the paraxialmesoderm and somites.
analysis of developmental expression of Xenopus paraxis

TCF15 Protein Profile

Protein Summary

The protein encoded by this gene is found in the nucleus and may be involved in the early transcriptional regulation of patterning of the mesoderm. The encoded basic helix-loop-helix protein requires dimerization with another basic helix-loop-helix protein for efficient DNA binding.

Alternative names and synonyms associated with TCF15

transcription factor 15 (TCF15)
transcription factor 15 (Tcf15)
transcription factor 15 L homeolog (tcf15.L)
transcription factor 15 (basic helix-loop-helix) (TCF15)
transcription factor 15 (tcf15)

bHLH-EC2 protein
bHLHa40 protein
BHLHEC2 protein
EC2 protein
meso1 protein
par1 protein
Paraxis protein
TCF-15 protein

Protein level used designations for TCF15

TCF-15 , basic helix-loop-helix transcription factor 15 , class A basic helix-loop-helix protein 40 , protein bHLH-EC2 , transcription factor 15 , paraxis , paraxis-like protein , bHLH-EC2 protein , Protein bHLH-EC2 , basic helix-loop-helix transcription factor , LOW QUALITY PROTEIN: transcription factor 15 , transcription factor 15 (basic helix-loop-helix)

GENE ID	SPECIES
6939	Homo sapiens
21407	Mus musculus
296272	Rattus norvegicus
493747	Xenopus laevis
395788	Gallus gallus
609667	Canis lupus familiaris
518491	Bos taurus
101826260	Mesocricetus auratus
100715168	Cavia porcellus
30159	Danio rerio

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