Protein Summary

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose\; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with B4GALT3

• beta-1,4-galactosyltransferase 3 (B4GALT3) antibody
• UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 S homeolog (b4galt3.S) antibody
• UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3 (B4galt3) antibody
• beta-1,4-galactosyltransferase 3 (B4galt3) antibody

• 9530061M23Rik antibody
• AA104562 antibody
• AW125175 antibody
• b4Gal-T3 antibody
• beta4Gal-T3 antibody
• Show all synonym aliases
• ESTM6 antibody
• ESTM26 antibody
• R74981 antibody

Protein level used designations for B4GALT3

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 3 , beta-1,4-galactosyltransferase 3 , UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3 , UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3 , b4Gal-T3 , beta-1,4-GalTase 3 , beta4Gal-T3 , beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 3 , N-acetyllactosamine synthase , UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3; beta-1,4-galactosyltransferase III; beta4GalT-III; expressed sequence tag mouse EST 6 , beta-1,4-galactosyltransferase III , beta4GalT-III , Beta-1,4-GalTase 3 , Beta4Gal-T3 , UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3