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anti-Human GLB1 Antibodies:
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Escherichia coli (E. coli) Monoclonal GLB1 Primary Antibody for ICC, WB - ABIN93909
Dráber, Slavícková, Sládecek, Viklický: Monoclonal antibodies to Escherichia coli beta-galactosidase and their use for detection and purification of recombinant expression products. in Hybridoma 1992
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Escherichia coli (E. coli) Polyclonal GLB1 Primary Antibody for IF, IP - ABIN1607729
Biju, Marks, Mast, Fadool: Deletion of voltage-gated channel affects glomerular refinement and odorant receptor expression in the mouse olfactory system. in The Journal of comparative neurology 2007
Bacteria Polyclonal GLB1 Primary Antibody for IHC (fro), IHC (p) - ABIN2477639
Meyers, Zepeda, Murdock: Alcohol and trauma. An endemic syndrome. in The Western journal of medicine 1990
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Bacteria Monoclonal GLB1 Primary Antibody for IA - ABIN259574
Chung, Kim, Andrew: Uncoupling apical constriction from tissue invagination. in eLife 2017
Bacteria Monoclonal GLB1 Primary Antibody for ELISA, ICC - ABIN251060
Durbin, Bodmer: A sensitive micro-immunoassay using beta-galactosidase/anti-beta-galactosidase complexes. in Journal of immunological methods 1987
Escherichia coli (E. coli) Polyclonal GLB1 Primary Antibody for DB, IP - ABIN99522
Shearer, Fragoso, Clagett-Dame, McCaffery: Astrocytes as a regulated source of retinoic acid for the brain. in Glia 2012
Functional loss of glucocerebrosidase (show GBA Antibodies) or beta-Gal promotes toxic conversion of alphaSyn via aberrant interactions between alphaSyn and their substrate glycolipids, leading to aggravation of alphaSyn-mediated neurodegeneration.
We confirmed a diagnosis of GM1 gangliosidosis based on GLB1 mutations and/or the deficiency of beta-galactosidase activity. We identified the first two cases by whole-exome sequencing, and then the other six cases by direct sequencing of GLB1 with enzyme analysis. The recurrent mutation, p.D448V in GLB1, accounted for 50.0% of total alleles in our cohort.
we showed for the first time the specific alteration of beta-Galctosidase (Gal (show GAL Antibodies)), beta-Galactosylcerebrosidase (GALC (show GALC Antibodies)) in MCI (show MCIN Antibodies) patients. It is notable that in above peripheral biological samples the lysosomes are more sensitive to AD cellular metabolic alteration when compared to levels of Abeta (show APP Antibodies)-peptide or Tau proteins, similar in both AD groups analyzed
GLB1 rs4678680 SNP contributes to susceptibility to develop HBV-related hepatocellular carcinoma
beta-Gal expression in articular cartilage is associated with progressive knee osteoarthritis joint damage and is a potential indictor of disease severity.
This study shows that moderate widespread expression of betagal in the CNS of GM1 gangliosidosis mice is sufficient to achieve significant biochemical impact with phenotypic amelioration and extension in lifespan
The study proposes an explanation for ELNR1 uncoupling based on the age-related alterations of Neu-1 (show NEU1 Antibodies) activity.
Overexpression of the novel senescence marker GLB1 in prostate cancer predicts reduced recurrence of PSA-expressing tumors.
Identification and analysis of GLB1 mutations in Indian patients with GM1 gangliosidosis.
We observed significant lower values of beta-galactosidase, FUC and tendency to decrease of MAN and GLU (show DCTN1 Antibodies) concentration in nasal polyps
This study analyzed patient cells with GM1 gangliosidosis and sialidosis. A novel mutation p.E186A is identified in GLB1 gene.
A significant proportion of p16Ink4a/senescence-associated beta-galactosidase-positive cells accumulating in aging mice are macrophages that acquired this phenotype as part of their physiological reprogramming towards an M2-like phenotype.
Senescence-associated-beta-gal activity in neurons cannot be attributed uniquely to cell senescence either in vitro or in vivo.
beta-gal is present in the pro-urine from where it is thought to stimulate TRPV5 (show TRPV5 Antibodies) activity.
Senescence-associated beta-galactosidase is present in apical vacuoles of visceral endoderm in developing mouse embryos.
We show here that mouse GLB1 has greater stability when compared to human GLB1, and that human GLB1 activity is temperature and protective-dependent on protein cathepsin A (show CTSA Antibodies), while that of mouse GLB1 is not
This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
, acid beta-galactosidase
, elastin receptor 1, 67kDa
, beta-galactosidase complex
, beta-galactosidase electrophoretic
, beta-galactosidase systemic regulator
, beta-galactosidase temporal
, lysosomal beta-galactosidase