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Expression of p53 (show TP53 Proteins) and Ki67 and presence or expression of EcPV2 and EcPV3 do not appear to be important prognosticators.
After intrastromal scanning of cornea, expression of Ki-67 increases.
injection of a b3-adrenergic receptor (b3-AR) agonist for continuous 5 days increased the number of Ki67-positive brown adipocytes even at Day 1 but not that of SV cells. In addition, the b3-AR antagonist, but not b1-AR antagonist, attenuated the cold exposure-induced increase in the number of Ki67-positive brown adipocytes
Ki67-positive cells are localized near inner enamel epithelium and supra-IEE, the stellate reticulum next to these is Ki67-negative. The IEE and supra-IEE contain intense Ki67-immunoreactivity, outer enamel epithelium lacks proliferative cells in mice.
Whey proteins reduced Ki-67 and 8-OHdG expression in the skin of chronically UVB-irradiated mice.
Both HDAC1 (show HDAC1 Proteins) and HDAC2 (show HDAC2 Proteins) play crucial roles in the regulation of liver regeneration. The loss of HDAC1 (show HDAC1 Proteins)/2 inhibits Ki67 expression and results in defective hepatocyte mitosis and impaired liver regeneration.
Intratumoral FLT uptake level markedly decreased at 6 h and then gradually increased with time.
Late stage cathepsin C (show CTSC Proteins), CXCL13 (show CXCL13 Proteins) and Ki-67 overexpression correlate with regional neuropathology in a bovine spongiform encephalopathy transgenic murine model.
The majority of tumours showed strong p16, p21, p27 (show CDKN1B Proteins), pRb (show PGR Proteins) and cyclin D1 (show CCND1 Proteins) staining and little or no p53 (show TP53 Proteins) expression. Tumours harbouring dysplasia were significantly more likely to be p53 (show TP53 Proteins)-positive and exhibit up-regulated p21 and p27 (show CDKN1B Proteins).
Vascular endothelial growth factor (VEGF (show VEGF Proteins)) expression correlates with p53 (show TP53 Proteins) and ki-67 expressions in tongue squamous cell carcinoma.
Age-related changes in proliferative markers in labial (show LAT2 Proteins) salivary glands: a study of argyrophilic nucleolar organizer regions (AgNORs) and Ki-67
p63 (show CKAP4 Proteins) protein is essential for the embryonic development of vibrissae and teeth; while it localizes with K5 in vibrissae, it is not fully colocalized with nuclear Ki67 expression
High Ki67, EZH2 (show EZH2 Proteins), and SMYD3 (show SMYD3 Proteins) immunoexpression, adjusted for standard clinicopathological parameters, independently predicts outcome in patients with prostate cancer, at diagnosis.
the combination of the TERT (show TERT Proteins) promoter/BRAFV600E mutations and Ki-67 LI is a promising marker to predict recurrence of PTC (show F9 Proteins).
p16/Ki-67 dual immunostaining had comparable sensitivity and improved specificity in screening high-grade cervical intraepithelial neoplasm (HGCIN) or CC when compared with hrHPV detection. Further studies may be beneficial to assess the efficacy of this novel biomarker, which can be potentially used as one of the initial screening assays.
We show that it is possible to approximate the true Ki67 Index accurately without detecting individual nuclei and also statically demonstrate the weaknesses of commonly adopted approaches that use both tumor and non-tumor regions together while compensating for the latter with higher order approximations
Prognosis of luminal breast carcinoma can be predicted using Ki67 as a continuous variable and a standard cut-off value of 14%. Information about the specimen type used to determine ki67 should be recorded in the pathological report
Ki-67 and TOPO 2A expression correlated with tumour size and tumour invasiveness in somatotropinomas.
The aim of this study was to investigate the expression of p16 and SATB1 (show SATB1 Proteins) proteins in regard to expression of the Ki-67 antigen and available clinicopathological data (i.a. receptor status, staging and grading
Data suggest that Ki-67 is a strong prognostic factor for overall survival (OS) and disease-free survival (DFS (show FST Proteins)) and should be included in all pancreatic neuroendocrine tumor pathology.
Ki-67-a proliferation marker is easily identified and provides comparable accurate information. In contrast to poor reproducibility of mitotic counts, Ki-67 can achieve high agreement between pathologists; is more reproducible; adds complementary value to the MBR (show TSPO Proteins) grading system and correlates well with other clinicopathologic parameters.
High Ki-67 expression is associated with papillary thyroid carcinoma.
This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X.
antigen identified by monoclonal antibody Ki-67
, antigen KI-67-like
, antigen KI-67
, proliferation-related Ki-67 antigen