Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human FNDC5 Antibodies:
anti-Mouse (Murine) FNDC5 Antibodies:
anti-Rat (Rattus) FNDC5 Antibodies:
Go to our pre-filtered search.
Human Polyclonal FNDC5 Primary Antibody for WB - ABIN1169430
Wrann, White, Salogiannnis, Laznik-Bogoslavski, Wu, Ma, Lin, Greenberg, Spiegelman: Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway. in Cell metabolism 2013
Human Polyclonal FNDC5 Primary Antibody for IF (p), IHC (p) - ABIN1387505
Park, Kim, Choi, Heo, Park: New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro. in Cellular signalling 2015
Human Polyclonal FNDC5 Primary Antibody for IHC, IHC (p) - ABIN4327646
Komolka, Albrecht, Schering, Brenmoehl, Hoeflich, Maak: Locus characterization and gene expression of bovine FNDC5: is the myokine irisin relevant in cattle? in PLoS ONE 2014
Neither FNDC5 nor its putatively secreted peptide irisin were found in circulation of bulls.
serum irisin levels were lower in Peritoneal Dialysis patients with Protein Energy Wasting than those of the patients without PEW
Data suggest that decreased irisin levels are associated with metabolic syndrome in prepubertal children; irisin may be a biomarker for metabolic syndrome in prepubertal children. This study was conducted in Seoul, Republic of Korea.
Findings revealed that irisin may play a critical role in the IL-6 (show IL6 Antibodies)-induced epithelialmesenchymal transition of osteosarcoma cells via the STAT3 (show STAT3 Antibodies)/Snail (show SNAI1 Antibodies) signaling pathway.
FNDC5 gene interactions with candidate genes FOXOA3 and APOE (show APOE Antibodies)
Irisin is negatively associated with serum testosterone in apopulation sample of men with Metabolic syndrome.
Irisin replenishment in mCaROCK1 mice partially reversed insulin (show INS Antibodies) resistance.
Suggest that irisin exerts beneficial effect on mood in COPD (show ARCN1 Antibodies) patients, possibly by inducing the expression of BDNF (show BDNF Antibodies) in brain areas associated with reward-related processes involved in by depression.
Modulation of Irisin and Physical Activity on Executive Functions in Obesity and Morbid obesity.
Obese children had significantly higher irisin and lower oxytocin levels than the healthy controls.
We determined FNDC5 polymorphisms frequencies in the Israeli population and demonstrated that maternal and neonatal FNDC5 rs726344 polymorphism is significantly associated with increased risk for preterm birth. Women bearing FNDC5 rs726344 GG genotype had 2.18 fold higher chance to deliver on time compared to AG and AA genotypes.Neonatal carrying FNDC5 rs726344 GG genotype had 2.24 fold higher chance to be born on time.
FNDC5 attenuated Oxidized low density lipoprotein-induced AMPK (show PRKAA1 Antibodies) deactivation, hepatic stellate cells activation, connective tissue growth factor (show CTGF Antibodies) and transforming growth factor-beta upregulation and extracellular matrix deposition in mouse hepatic stellate cells.
the coordinated expression of FNDC5 and PGC-1alpha may contribute to the increased levels of plasma irisin after exercise.
Irisin(Fndc5) increases myogenic differentiation and myoblast fusion via activation of IL6 (show IL6 Antibodies) signaling.
FNDC5 is overexpressed in skeletal muscle and adipose tissue of insulin (show INS Antibodies) resistant high fat-fed mice.
This study for the first time showed that adipocytes are directly affected by irisin (Fndc5) and provides an evidence on anti-inflammatory action of irisin on fat cells.
Mstn (show MSTN Antibodies) regulates Fndc5/Irisin expression and secretion through a novel miR (show MLXIP Antibodies)-34a-dependent post-transcriptional mechanism; loss of Mstn (show MSTN Antibodies) in mice leads to the increased Fndc5/Irisin expression, which contributes to the browning of white adipocytes
The secretion of FNDC5 from myotubes and beta-cells in response to exogenous fatty acids, the effects of recombinant FNDC5 on insulin (show INS Antibodies) biosynthesis and glucose-stimulated insulin (show INS Antibodies) secretion, and beta-cell apoptosis are reported.
Irisin is upregulated in a murine model of fibrosis, but not in experimental NAFLD (show TSC2 Antibodies) without significant fibrosis.
Irisin improved endothelial function by modulating HO-1 (show HMOX1 Antibodies)/ adiponectin axis in perivascular adipose tissue (PVAT) in HFD-induced obese mice. These findings suggest that regulating PVAT function may be a potential mechanism by which irisin improves endothelial function in obesity.
results are the first to demonstrate that the protective effects of irisin in cardiomyoblasts exposed to hypoxia/reoxygenation might be associated with HDAC4 (show HDAC5 Antibodies) degradation.
these results indicate that unaltered endogenous irisin is required to maintain food intake in zebrafish.[irisin]
mouse homolog is linked to myoblast differentiation and development
fibronectin type III domain-containing protein 5
, fibronectin type III domain containing 5
, fibronectin type III repeat-containing protein 2
, peroxisomal protein