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Human DPEP1 Protein expressed in Human Cells - ABIN2005783
Liao-Chan, Zachwieja, Gomez, Duey, Lippincott, Theunissen: Monoclonal antibody binding-site diversity assessment with a cell-based clustering assay. in Journal of immunological methods 2014
The results suggest that DPEP1 promotes cancer metastasis by regulating E-cadherin (show CDH1 Proteins) plasticity and that it might be a potential therapeutic target for preventing the progression of colon cancer.
In this study, we present an analysis of Neanderthal introgression at the dipeptidase 1 gene, DPEP1.
Dipeptidase 1 has been identified as an excellent marker of high-grade IEN and CRC (show CALR Proteins), and may thus be applied for screening of early neoplastic lesions and for prognostic stratification.
DPEP1 plays a role in pancreatic cancer aggressiveness.
DPEP1 is expressed in the early stages of colon carcinogenesis and affects cancer cell invasiveness.
we identified a novel immunohistochemical marker, dipeptidase 1, to distinguish primary mucinous ovarian cancers from ovarian metastasis of colorectal cancers.
CPS1 (show CPS1 Proteins), MUT (show MUT Proteins), NOX4 (show NOX4 Proteins), and DPEP1 is associated with plasma homocysteine in healthy Women.
Crystal structure of human renal dipeptidase involved in beta-lactam hydrolysis
DPEP1 has a role in colorectal carcinoma
Association of GPI (show GPI Proteins)-anchored membrane dipeptidase with detergent-resistant membranes facilitates its trafficking through the early secretory pathway, at a level between the endoplasmic reticulum and the cis (show CISH Proteins)-Golgi.
The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene.
dipeptidase 1 (renal)
, dipeptidase 1
, membrane-bound dipeptidase 1
, microsomal dipeptidase
, renal dipeptidase
, 43 kDa renal band 3-related protein
, 43-KDa rabbit renal band 3-related protein