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DPEP1 Protein (His tag)

DPEP1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318407
  • Target See all DPEP1 Proteins
    DPEP1 (Dipeptidase 1 (Renal) (DPEP1))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 2
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This DPEP1 protein is labelled with His tag.
    Purpose
    Recombinant Human Dipeptidase 1/DPEP1 Protein (His Tag)
    Sequence
    Asp17-Ser385
    Characteristics
    Recombinant Human Dipeptidase 1 is produced by our Mammalian expression system and the target gene encoding Asp17-Ser385 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product DPEP1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    DPEP1 (Dipeptidase 1 (Renal) (DPEP1))
    Alternative Name
    Dipeptidase 1/DPEP1 (DPEP1 Products)
    Synonyms
    AI327012 Protein, MBD Protein, MBD1 Protein, MDP Protein, RDP Protein, dipeptidase 1 (renal) Protein, dipeptidase 1 Protein, DPEP1 Protein, Dpep1 Protein
    Background

    Background: Dipeptidase 1 (DPEP1) is a kidney membrane enzyme that belongs to the peptidase M19 family. DPEP1 is a homodimer and is inhibited by L-penicillamine. DPEP1 hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates. DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem. DPEP1 may play an important role in the regulation of leukotriene activity. DPEP1 expression in cancer is significantly higher than that in normal tissue. However, DPEP1 expression decreased with pathological differentiation, lymph-node and distant metastasis.

    Synonym: Dipeptidase 1, Dehydropeptidase-I, Microsomal Dipeptidase, Renal Dipeptidase, hRDP, DPEP1, MDP, RDP, MBD1

    Molecular Weight
    42.1 kDa
    UniProt
    P16444
    Pathways
    Inositol Metabolic Process
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