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Browse our anti-Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) Antibodies

Full name:: anti-Phosphatidylinositol 4-Kinase Type 2 beta Antibodies (PI4K2B)

On www.antibodies-online.com are 32 Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) Antibodies from 7 different suppliers available. Additionally we are shipping Phosphatidylinositol 4-Kinase Type 2 beta Proteins (5) and and many more products for this protein. A total of 44 Phosphatidylinositol 4-Kinase Type 2 beta products are currently listed.

Synonyms:: 2610042N09Rik, 4933409G22Rik, GB16449, PI4KIIB, PIK42B, zgc:158305

list all antibodies	Gene Name	GeneID	UniProt
	PI4K2B	55300	Q8TCG2
	PI4K2B	67073	Q8CBQ5
	PI4K2B	305419	Q5XIL2
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Most Popular Reactivities for anti-Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) Antibodies

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anti-Human Antibodies:

32 WB Antibodies

anti-Mouse (Murine) Antibodies:

18 WB Antibodies

anti-Rat (Rattus) Antibodies:

8 WB Antibodies

All available anti-Phosphatidylinositol 4-Kinase Type 2 beta Antibodies

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Relevant Pathways for anti-Phosphatidylinositol 4-Kinase Type 2 beta Antibodies

Inositol Metabolic Process

More product categories related to Phosphatidylinositol 4-Kinase Type 2 beta Antibody

Top referenced anti-Phosphatidylinositol 4-Kinase Type 2 beta Antibodies

Human Polyclonal PI4K2B Primary Antibody for IHC (p), ELISA - ABIN544188 : Balla, Tuymetova, Barshishat, Geiszt, Balla: Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments. in The Journal of biological chemistry 2002 (PubMed)
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Human Polyclonal PI4K2B Primary Antibody for IHC (p), ELISA - ABIN544187 : Mora, Durham, Smith, Russo, Jeromin, Pessin: NCS-1 inhibits insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes through a phosphatidylinositol 4-kinase-dependent pathway. in The Journal of biological chemistry 2002 (PubMed)
Show all 3 Pubmed References

More Antibodies against Phosphatidylinositol 4-Kinase Type 2 beta Interaction Partners

Human Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) interaction partners

RNA interference of the type II phosphatidylinositol 4-kinases PI4KIIa and PI4KIIa in primary human endothelial cells leads to formation of an increased proportion of short WPB with perturbed packing of VWF, as exemplified by increased exposure of antibody-binding sites.
Here two crystal structures are presented: the structure of human PIK42A and the structure of PIK42B containing a nucleoside analogue.
Results provide evidence that type II PtdIns 4-kinase b was indeed recruited to CD4- p56lck complex upon CD4 receptor cross linking, suggests a mechanism for its association and a role for it in CD4-mediated intracellular calcium release.
Canonical tyrosine residues mutation in FcepsilonRIgamma ITAM (Y65 and Y76) reveals that these two tyrosine residues in gamma subunit are required for its interaction with type II PtdIns 4-kinases.
type II PtdIns 4-kinase beta is a key component in early T cell activation signaling cascades
PIP4Kbeta interacts with and modulates nuclear localization of the PIP4Kalpha.
There is no evidence to suggest that PI4K2B is contributing to bipolar disorder in this family but a role for this gene in schizophrenia has not been excluded.
Type II PtdIns 4-kinase beta interacts with TCR-CD3 zeta chain. The C-terminal ITAM is critical for enzyme docking on the zeta chain. The association is tyrosyl phosphorylation dependent. Mutation of Y-151 & Y-142 disrupts interaction of the 2 proteins.
UV irradiation increases nuclear PtdIns5P levels via inhibition of the activity of the beta isoform of PtdIns5P 4-kinase (PIP4Kbeta), an enzyme that can phosphorylate and remove PtdIns5P.
LB-PI4K2B-1S-specific CD4(+) T cells contributed to the antitumor response by both directly eliminating malignant cells as effector cells and stimulating CD8(+) T cell immunity as helper cells.

Mouse (Murine) Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) interaction partners

PI 4-kinase functions to negatively regulate GLUT4 translocation through its interaction with NCS-1.
UV irradiation increases nuclear PtdIns5P levels via inhibition of the activity of the beta isoform of PtdIns5P 4-kinase (PIP4Kbeta), an enzyme that can phosphorylate and remove PtdIns5P.

Zebrafish Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) interaction partners

PI4-kinase type 2beta (PI4K2beta) is identified as a regulator of the trans-Golgi network (TGN)/endosomal sorting and Wnt signaling. PI4K2beta and AP-1 interact directly and are required for efficient sorting between endosomes and the TGN.

Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B) Antigen Profile

Antigen Summary

Phosphatidylinositol 4-kinases (PI4Ks) phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate (PIP), an immediate precursor of several important signaling and scaffolding molecules. PIP itself may also have direct functional and structural roles. PI4K2B is a primarily cytosolic PI4K that is recruited to membranes, where it stimulates phosphatidylinositol 4,5-bisphosphate synthesis (Wei et al., 2002

Alternative names and synonyms associated with Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B)

uncharacterized LOC725812 (LOC725812) antibody
phosphatidylinositol 4-kinase type 2 beta L homeolog (pi4k2b.L) antibody
phosphatidylinositol 4-kinase type 2 beta (PI4K2B) antibody
phosphatidylinositol 4-kinase type 2 beta (pi4k2b) antibody
phosphatidylinositol 4-kinase type 2 beta (Pi4k2b) antibody

2610042N09Rik antibody
4933409G22Rik antibody
GB16449 antibody
PI4KIIB antibody
PIK42B antibody
zgc:158305 antibody

Protein level used designations for PI4K2B

phosphatidylinositol 4-kinase type 2-beta , phosphatidylinositol 4-kinase type II-beta , phosphatidylinositol 4-kinase type 2 beta , phosphatidylinositol 4-kinase type 2-beta-like , PI4KII-BETA , phosphatidylinositol 4-kinase type-II beta , type II phosphatidylinositol 4-kinase beta , PI4KII-beta , phosphatidylinositol 4-kinase II beta , pi4kII beta

GENE ID	SPECIES
725812	Apis mellifera
446885	Xenopus laevis
521790	Bos taurus
549707	Xenopus (Silurana) tropicalis
100345479	Oryctolagus cuniculus
100408979	Callithrix jacchus
100591265	Nomascus leucogenys
100623115	Sus scrofa
55300	Homo sapiens
67073	Mus musculus
305419	Rattus norvegicus
422807	Gallus gallus
564750	Danio rerio

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