Browse our anti-DAB2 (DAB2) Antibodies

Human Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) interaction partners

1. DAB2 might be involved in excessive aldosterone biosynthesis and correlate with specific clinical characteristics of aldosterone-producing adenoma patients.

2. the results indicated that substrate stiffness could regulate EMT (show ITK Antibodies) of cervical cancer cell lines HeLa and SiHa at least partially through miR (show MLXIP Antibodies)-106b and its downstream target DAB2.

3. DAB2 can suppress the ERK (show EPHB2 Antibodies) signaling, but correlate to have TGF-beta (show TGFB1 Antibodies)-induced epithelial-to-mesenchymal transition (EMT (show ITK Antibodies)) in esophageal squamous cell carcinomas (ESCCs).

4. The various novel mechanisms are described by which Dab2 mediates an array of signaling events with vast physiological consequences.

5. In conclusion, DAB2 and Intelectin-1 (show ITLN1 Antibodies) are newly identified positive markers of mesothelioma and have potential to be included in future immunohistochemical marker panels for differentiation of epithelioid mesothelioma from pulmonary adenocarcinoma

6. cathepsin B (CTSB (show CTSB Antibodies)) inhibition or expression of a CTSB (show CTSB Antibodies)-resistant Dab2 mutant maintains Dab2 expression and shifts long-term TGF-beta (show TGFB1 Antibodies)-treated cells from autophagy to apoptosis

7. abundances of megalin (show LRP2 Antibodies) and Dab2 (p = 0.046) were reduced in infected placentas from women with LBW deliveries

8. Data show that miR106b was frequently up-regulated in human cervical carcinoma tumors and cell lines and inversely correlated with DAB2 expression. Its regulation in under TGF-beta1 (show TGFB1 Antibodies) which contributes to cell migration by targeting DAB2 in cervical carcinoma.

9. these findings reveal that DAB2 is critical for controlling inflammatory signaling during phenotypic polarization of macrophages

10. inhibition of WNT (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling by DAB2 is essential for establishing the correct number of cardiomyocytes in the developing heart.

Mouse (Murine) Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) interaction partners

1. The various novel mechanisms are described by which Dab2 mediates an array of signaling events with vast physiological consequences.

2. The combination of Arh (show LDLRAP1 Antibodies) and Dab2 is responsible for the majority of adaptor function in LDLR (show LDLR Antibodies) endocytosis and LDLR (show LDLR Antibodies)-mediated cholesterol homeostasis.

3. cathepsin B (CTSB (show CTSB Antibodies)) inhibition or expression of a CTSB (show CTSB Antibodies)-resistant Dab2 mutant maintains Dab2 expression and shifts long-term TGF-beta (show TGFB1 Antibodies)-treated cells from autophagy to apoptosis

4. Results identified a novel activation marker, DAB2, which expression is significantly different between microglia activation stages M2a and either M1 or M2b.

5. these findings reveal that DAB2 is critical for controlling inflammatory signaling during phenotypic polarization of macrophages

6. Dab2 expression is induced by hormones

7. Results suggest that endogenous Dab2 exacerbates central nervous system inflammation, potentially acting to up-regulate reactive oxygen species expression in macrophages and microglia, and that it is of potential pathogenic relevance in multiple sclerosis

8. Disabled-2 is required for efficient hemostasis and platelet activation by thrombin (show F2 Antibodies) in mice.

9. Akt1 (show AKT1 Antibodies) and Akt2 (show AKT2 Antibodies) are involved in albumin (show ALB Antibodies) endocytosis, and phosphorylation of Dab2 by Akt (show AKT1 Antibodies) induces albumin (show ALB Antibodies) endocytosis in proximal tubule epithelial cells.

10. Study of dab2 mutant allele in embryos and embryoid bodies confirms a role for Dab2 in extraembryonic endoderm development and epithelial organization. Also, Dab2 has a physiological role in the endocytosis of lipoproteins and cholesterol metabolism.

Cow (Bovine) Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) interaction partners

1. Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Antibodies) and PTGS2 (show PTGS2 Antibodies), and decreased the expression of SOD2 (show SOD2 Antibodies), GPX3 (show GPX3 Antibodies), DAB2, and NR3C1 (show NR3C1 Antibodies). TNF (show TNF Antibodies) and IL6 (show IL6 Antibodies) levels were also decreased while those of NAMPT (show NAMPT Antibodies) were unaffected.