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anti-Human Angiotensin II Type-1 Receptor Antibodies:
anti-Mouse (Murine) Angiotensin II Type-1 Receptor Antibodies:
anti-Rat (Rattus) Angiotensin II Type-1 Receptor Antibodies:
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Human Polyclonal Angiotensin II Type-1 Receptor Primary Antibody for ICC, IF - ABIN4278728
Miyazaki, Ichikawa: Role of the angiotensin receptor in the development of the mammalian kidney and urinary tract. in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2001
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Dog (Canine) Polyclonal Angiotensin II Type-1 Receptor Primary Antibody for IHC, ELISA - ABIN1582292
Mateos, Ismail, Gil-Bea, Schüle, Schöls, Heverin, Folkesson, Björkhem, Cedazo-Mínguez: Side chain-oxidized oxysterols regulate the brain renin-angiotensin system through a liver X receptor-dependent mechanism. in The Journal of biological chemistry 2011
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Human Polyclonal Angiotensin II Type-1 Receptor Primary Antibody for IHC, ELISA - ABIN188713
Marut, Kavian, Servettaz, Hua-Huy, Nicco, Chéreau, Weill, Dinh-Xuan, Batteux: Amelioration of systemic fibrosis in mice by angiotensin II receptor blockade. in Arthritis and rheumatism 2013
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Human Polyclonal Angiotensin II Type-1 Receptor Primary Antibody for IHC, IHC (p) - ABIN4278729
Unthank, McClintick, Labarrere, Li, Distasi, Miller: Molecular basis for impaired collateral artery growth in the spontaneously hypertensive rat: insight from microarray analysis. in Physiological reports 2013
no statistical association with kidney graft failure was found for anti-AT1R antibodies, indicating that these tests may not be the best predictors of graft outcome in living donor renal transplantation.
Inhibition of CaV1.2 (show CACNA1C Antibodies) upregulates AT1R signaling in response to angiotensin II.
Single nucleotide polymorphisms of AGTR1 gene are associated with Hypertension.
The presence of AGTR1 autoantibodies is an independent predictor for aortic stiffness progression in normotensive subjects.
The DEGs (show DEGS1 Antibodies), such as AGTR1, CYP3A4 (show CYP3A4 Antibodies) and CYP4A11 (show CYP4A11 Antibodies) may play critical roles in the development of HTN likely via the regulation by hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-26b-5p and taking part in some pathways.
Low shear stress induces the generation of endothelial reactive oxygen species via AT1R/eNOS (show NOS3 Antibodies)/NO signaling pathway.
Low AGTR1 expression is associated with chemoresistance of osteosarcoma.
No relationship was found between the studied polymorphisms (14094 ACE (show ACE Antibodies) gene, rs1800469 gene TGFbeta1 (show TGFB1 Antibodies), GNB3 (show GNB3 Antibodies) gene rs5443, rs5186 AGTR1 gene) and the occurrence of primary vesicoureteral reflux.
Angiotensin II type 1 receptors promote ADAM17 (show ADAM17 Antibodies)-mediated ACE2 (show ACE2 Antibodies) shedding in the brain of hypertensive patients.
Data suggest that allosteric communication between heterodimeric AT1R and PTGFR is mediated through GNAQ and may also involve proximal phospholipase C but not distal protein kinase C signaling partners; PTGFR activation has negligible effects on AT1R-based conformational biosensors. (AT1R = angiotensin II receptor, type 1; PTGFR = prostaglandin F2alpha receptor; GNAQ = GTP-binding protein G[q] subunit alpha)
Nrf2 (show NFE2L2 Antibodies)-mediated stimulation of intrarenal Renin (show REN Antibodies)-angiotensin system gene expression, by which chronic hyperglycemia induces hypertension and renal injury in diabetes.
This study aimed to define whether sex chromosome complement (SCC (show CYP11A1 Antibodies)) may differentially modulate sex differences in relative gene expression of basal Agtr1a, Agtr2 (show AGTR2 Antibodies), and Mas1 (show MAS1 Antibodies) receptors at fore/hindbrain nuclei and at medulla/cortical kidney.
The formation of liver metastasis, in a mouse model of colorectal cancer, correlated with collagen deposition in the metastatic area, which was dependent on AT1a (show AGTR1a Antibodies) signaling.
Perivascular Adipose Tissue Angiotensin II Type 1a Receptor (show AGTR1a Antibodies) Promotes Vascular Inflammation and Aneurysm formation in apolipoprotein E (show APOE Antibodies)-deficient (ApoE (show APOE Antibodies)(-/-)) mice.
The findings suggested that ox-LDL could induce cardiac hypertrophy through the direct association of AT1-R and LOX-1 (show OLR1 Antibodies).
Mice lacking the AT1A (show AGTR1a Antibodies) receptor specifically in LEPR (show LEPR Antibodies)-expressing cells failed to show an increase in resting metabolic rate in response to a high-fat diet and deoxycorticosterone acetate-salt (DOCA-salt) treatments, but blood pressure control remained intact.
In wild-type, total (tNCC (show TNNC1 Antibodies)) and phosphorylated (pNCC) NCC (show SLC12A3 Antibodies) protein expressions were 1.8- and 4.6-fold higher in females compared with males, consistent with the larger response to HCTZ. In AT1a (show AGTR1a Antibodies) receptor knockout mice, tNCC (show TNNC1 Antibodies) and pNCC increased significantly in males to levels not different from those in females.
This study showed that activation of the AT1a (show AGTR1a Antibodies) receptor may contribute to maintenance of the glomerular structure against hypertensive renal damage.
Altered expression of AT1 and AT2 receptors with aging may induce mitochondrial dysfunction, the main risk factor for neurodegeneration.
Results provide evidence that blockade of the AT1a (show AGTR1a Antibodies) receptor could have some effects on browning of WAT, with inhibitory effects on adipose tissue-derived stem cells differentiation into adipocytes.
Data suggest that AGTR2 (show AGTR2 Antibodies) (and angiotensin-converting enzyme (show ACE Antibodies)) mRNA levels are transiently up-regulated in ovarian theca cells during preovulatory period.
These results identify bTREK-1 K(+) channels as a pivotal control point where ANG II (show AGT Antibodies) receptor activation is transduced to depolarization-dependent Ca(2 (show CA2 Antibodies)+) entry and aldosterone secretion.
Angiotensin II (ANGII) inhibits adrenocortical cell KCNK2 in an ATP dependent, PLC/PKC independent manner.
data suggest that G alpha(i3), Shc (show SHC1 Antibodies), Grb2 (show GRB2 Antibodies), Ras, and Raf-1 (show RAF1 Antibodies) link Src (show SRC Antibodies) to activation of MAPK (show MAPK1 Antibodies) and to the AT(2)-dependent increase in eNOS (show NOS3 Antibodies) expression in PAECs
Abundance of AGTR2 (show AGTR2 Antibodies) mRNA in granulosa cells was higher in healthy compared with atretic follicles, whereas in theca cells, it did not change
transcripts for the ANGII receptor type 1 (ATR1) were detected in lungs of Xenopus laevis
Ang II (show AGT Antibodies) increase HTFs proliferation, migration, and phenotype transition, suggesting that Ang II (show AGT Antibodies) may play a role in wound healing after trabeculectomy.
Renal AT1R expression was increased by approximately 67% and AT2R (show AGTR2 Antibodies) expression was decreased by approximately 87% in rabbits with heart failure; however, kidneys from denervated rabbits with heart failure showed a near normalization in the expression of these receptors.
Atrial fibrillation induces myocardial fibrosis through angiotensin II type 1 receptor-specific Arkadia (show RNF111 Antibodies)-mediated downregulation of Smad7 (show SMAD7 Antibodies).
Following inflammation in the femoral artery angiotensin AT1 receptors are activated along with thromboxane receptors.
Corneal cells express ACE (show ACE Antibodies), AT(1) and AT(2)receptors. ACE (show ACE Antibodies) inhibitor enalapril decreased corneal angiogenesis in VEGF (show VEGFA Antibodies)-induced corneal neovascularization. ACE (show ACE Antibodies) inhibitors may be novel therapy to treat corneal angiogenesis.
investigated whether oxidant stress plays a role in Ang II-induced AT1R upregulation and its relationship to the transcription factor activator protein 1 (AP1) in CHF rabbits and in the CATHa neuronal cell line
Luminal ANG II is internalized as a complex with AT1R/AT2R heterodimers to target endoplasmic reticulum in LLC-PK1 cells, where it might trigger intracellular calcium responses.
AT1 and AT2 (show AGTR2 Antibodies) receptors heterodimerize and are involved in the angiotensin II effect on SERCA (show ATP2A3 Antibodies) in proximal kidney tubules.
A critical role for lipid raft microdomains in AGTR1-mediated signal transduction in neonatal glomerular mesengial cells.
AT1 receptors are positively coupled to the proliferative response of vascular smooth muscle cells to angiotensin II.
Glomerular eNOS (show NOS3 Antibodies) gene expression was studied during postnatal maturation and AT1 receptor (show AGTRAP Antibodies) inhibition.
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed\; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.
type-1 angiotensin II receptor
, type-1B angiotensin II receptor
, angiotensin II type-1A receptor
, angiotensin receptor 1
, angiotensin receptor 1a
, type-1A angiotensin II receptor
, Angiotensin II receptor, type 1 (AT1B)
, angiotensin II receptor, type-1
, angiotensin II type-1 receptor
, angiotensin II type-1B receptor
, angiotensin receptor 1b
, angiotensin II receptor 1
, angiotensin 2 receptor, type 1, gene 2
, angiotensin 2 receptor, type 1-B
, angiotensin II receptor, type 1
, angiotensin II receptor, type 1-B
, angiotensin II type-1 receptor 2
, angiotensin type 1 receptor
, type-1 angiotensin II receptor B
, type-1-like angiotensin II receptor 2
, angiotensin II type 1 receptor
, AT1 ANG II receptor
, AT1 angiotensin II receptor
, Type-1 angiotensin II receptor
, angiotensin receptor
, angiotensin II receptor type 2
, angiotensin II type 2 receptor
, angiotensin receptor 2
, angiotensin II receptor, type 2
, type-2 angiotensin II receptor
, angiotensin type II receptor
, type-2 angiotensin II receptor-like
, Type-2 angiotensin II receptor
, angiotensin II subtype 2 receptor, AT2
, Angiotensin II type-1 receptor
, Angiotensin 2 receptor, type 1-A
, Angiotensin II receptor, type 1-A
, Type-1-like angiotensin II receptor 1
, angiotensin 2 receptor, type 1 L homeolog
, angiotensin 2 receptor, type 1-A
, angiotensin II receptor, type 1-A
, angiotensin II type-1 receptor 1
, angiotensin type 1
, type-1 angiotensin II receptor A