Angiotensin II Type-1 Receptor antibody (AA 37-86)

Catalog No. ABIN6740751

Product Details anti-Angiotensin II Type-1 Receptor Antibody

Target: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Binding Specificity: AA 37-86

Reactivity: Human, Rat, Mouse, Dog, Rabbit, Guinea Pig, Cow, Sheep, Bat, Monkey, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiotensin II Type-1 Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human AGTR1

Predicted Reactivity: Percent identity by BLAST analysis: Human, Sheep, Dog, Bovine, Rabbit, Guinea pig (100%) Mouse, Pig (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa37-86 of human AGTR1 (P30556, NP_004826). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Guinea pig (100%), Galago, Horse, Pig (92%), Opossum (84%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:62500.

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for Angiotensin II Type-1 Receptor

Target: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Alternative Name: AGTR1 / AT1 Receptor (AGTR1 Products)

Synonyms: AG2S antibody, AGTR1A antibody, AGTR1B antibody, AT1 antibody, AT1AR antibody, AT1B antibody, AT1BR antibody, AT1R antibody, AT2R1 antibody, AT2R1A antibody, AT2R1B antibody, HAT1R antibody, 1810074K20Rik antibody, AI551199 antibody, AT1a antibody, Agtr-1a antibody, Agtr1 antibody, Angtr-1a antibody, AT1A antibody, XAT-1 antibody, agtr1-A antibody, agtr1.2 antibody, AT1-R antibody, at1 antibody, AGTR1 antibody, Agtr-1b antibody, Angtr-1b antibody, agtr1 antibody, agtr1-a antibody, agtr1-b antibody, xAT antibody, angiotensin II receptor type 1 antibody, angiotensin II receptor, type 1a antibody, angiotensin II receptor type 1 S homeolog antibody, uncharacterized AGTR1 antibody, angiotensin II receptor, type 1b antibody, angiotensin II receptor type 1 L homeolog antibody, AGTR1 antibody, Agtr1a antibody, agtr1.S antibody, Agtr1 antibody, Agtr1b antibody, agtr1.L antibody

Background: Name/Gene ID: AGTR1
Subfamily: Angiotensin
Family: GPCR

Synonyms: AGTR1, AG2S, AGTR1A, AGTR1B, Angiotensin II type-1 receptor, Ang ii receptor type 1a, Angiotensin receptor 1, Angiotensin receptor 1a, Angiotensin receptor 1B, AT1R, AT1 receptor, At1a receptor, AT1B, AT1AR, AT2R1, AT2R1A, AT2R1B, HAT1R, AT1, At1a, At1b receptor, AT1BR, Type-1 angiotensin II receptor

Gene ID: 185

NCBI Accession: NP_004826

UniProt: P30556

Pathways: JAK-STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour