Browse our anti-IL5 (IL5) Antibodies

Human Interleukin 5 (IL5) interaction partners

1. The luteal phase of the cycle in perimenstrual asthma patients is associated with increased serum estradiol levels with concurrent higher sputum concentration of IL-5 and IL-8.

2. The concentration of Th2-related cytokines (IL-5 and IL-13) in asthmatic children with Rhinovirus(+) was significantly higher than those with Rhinovirus(-).

3. IL-5 is expressed intrathecally in tick-borne encephalitis, but its pathogenetic role remains unclear.

4. eosinophilia in FE is secondary to dysregulation of IL-5 production in PBMC (and their component subsets).

5. Data indicate that interleukin-5 (IL-5) was that only serum cytokines show statistical significance between severe chronic obstructive pulmonary disease (COPD) and controls.

6. Serum IL-5 and IL-13 are reliable biomarkers for the blood eosinophilia asthma phenotype.

7. Longitudinal co-variations between inflammatory cytokines, lung function and patient reported outcomes in patients with asthma

8. Obesity alters the lung neutrophil infiltration to enhance breast cancer metastasis through IL5 and GM-CSF.

9. simvastatin was demonstrated to inhibit IL-5-induced CCR3 expression and chemotaxis of eosinophils mediated via the mevalonate pathway.

10. Interleukin-5/-targeted treatments offer promises to patients with eosinophilic respiratory disorders; review

11. Data indicate that interleukin 5 (IL-5)-associated single nucleotide polymorphisms (SNPs) were not associated with carotid intima-media thickness.

12. Post-liver transplant patients with food allergy showed a unique cytokine profile in response to various stimuli, with extremely elevated IL-5, low IL-10 secretion.

13. high levels of IL-33 and a high IL-33/soluble ST2 ratio correlates with elevated levels of IFN-gamma, TNF-alpha and IL-17alpha as well as IL-5, demonstrating that IL-33 has pleiotropic effects.

14. Production of IL-5 in response to both extract and the Bet v1-derived peptide mix strongly suggested that T cells were a major source of IL-5.

15. TRPV1 expression level, IL-4 level, and rs4790522 site mutation are the main risk factors inducing bronchial asthma in children

16. It has been shown in this study that the level of IL-5, one of the markers of eosinophilic inflammation, is higher in EBC of children with atopic asthma than in those with nonatopic asthma.

17. IL-5 may be part of protective mechanisms operating in early atherosclerosis, at least in women

18. Results showed that PAX2 expression is significantly overexpressed in esophageal squamous cell carcinoma tissues and IL-5 is identified as PAX2's effector for metastasis.

19. At a fixed concentration of 10-10 M, FF had significantly higher suppressive effects on interferon (IFN)-gamma, interleukin (IL)-2 and IL-17 release, but not IL-5 or tumor necrosis factor (TNF)-alpha, vs. MF.

20. There was an improvement of the in vitro-cytokine responses in iL-5, IL-10, and interferon-gamma after liver transplantations in end-stage liver disease pediatric patients.

Mouse (Murine) Interleukin 5 (IL5) interaction partners

1. These data indicate that mice deficient for IL-4R(-/-)/IL-5(-/-) have the highest susceptibility for Litomosoides sigmodontis infection.

2. we have studied the gene expression changes associated with IL-5 up-regulation in eosinophils

3. binding of IL-5 to IL-5Ralpha receptors enhances angiogenic responses by stimulating the expression of HSP70-1 via the eNOS signaling pathway.

4. Both pre- and post-transcriptional processes may be involved in the AR modulation of ILC2 IL-5 and IL-13 production.

5. IL-33 acts directly on bone marrow ILC2s, making them an early source of IL-5 and part of a process that is central in IL-33-driven eosinophilia.

6. Obesity alters the lung neutrophil infiltration to enhance breast cancer metastasis through IL5 and GM-CSF.

7. these studies establish a basal defect in eosinophilopoiesis in IL-33- and ST2-deficient mice and a mechanism whereby IL-33 supports eosinophils by driving both systemic IL-5 production and the expansion of IL-5Ralpha-expressing precursor cells

8. Increased production of IL-5 from Peyer's patch cells and the restored Th1-type immune response might cause the production of abnormal IgA and might induce the glomerular deposition of IgA in IGA nephropathy.

9. E. granulosus infection remarkably reduces the severity of OVA-induced airway inflammation likely through enhancing IL-10 and down-regulation of IL-5 and IL-17A.

10. selective proliferation of IgM rheumatoid factor-secreting B-1a cells is induced by co-stimulation by the specific pathogen antigen and IL-5 in the development of MC in Capillaria hepatica-infected mice

11. IL5, a cytokine involved in allergic and infectious diseases, facilitates metastatic colonization through recruitment of sentinel eosinophils and regulation of other inflammatory/immune cells in the microenvironment of the distal lung.

12. In mice, low-dose IL-2-anti-IL-2 antibody complexes drove group 2 innate lymphoid cells (ILC2) to produce IL-5 and proliferate.

13. Data (including data from knockout mice) suggest that up-regulation of IL5 production in lungs during influenza virus infection is due to infiltration of natural killer cells and alveolar macrophages into infected lung tissue.

14. A decrease in the levels of IL-5, IL-9, and IL-6R in the BALF.

15. eosinophils express CAR4 following IL-5 or allergen exposure, and that CAR4 is involved in regulating the lung transcriptome associated with allergic airway inflammation

16. Loa loa exhibits a differential survival and development in different strains of cytokine or cytokine receptor gene knockout mice with IL-4R and IL-5 playing critical roles in the host resistance to L. loa infection.

17. In mice 8 hours afterthe single administration of Immunovac-VP-4 the levels of IL-1beta, IL-6, IL- 12, IL-5 increased significantly. However their concentration differed depending on the method of administration.

18. Protection of montelukast on OVA-induced eosinophilic gastroenteritis via modulating IL-5, eotaxin-1 and MBP expression.

19. Together, these studies support the conclusion that surfactant protein D increases susceptibility to Cryptococcus neoformans infection by promoting Cryptococcus neoformans-driven pulmonary IL-5 and eosinophil infiltration.

20. IL5 induced eosinophils and cysteinyl leukotrienes are involved in the pathology of mite antigen-induced chronic asthma model.

Horse (Equine) Interleukin 5 (IL5) interaction partners

1. This study showed that pronounced lung eosinophilia in horses can be transient, abate without specific treatment, and in this instance, lack correlation to upregulation of expression of either IL-4 or IL-5.