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STAT3 Proteins

(Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].

recommended

STAT3 Protein (AA 1-769) (GST tag) (ABIN1321594)

STAT3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

STAT3 Protein (AA 1-177) (His tag) (ABIN7125094)

STAT3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

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recommended

STAT3 Protein (AA 670-769) (GST tag) (ABIN1321596)

STAT3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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STAT3 Proteins by Origin

Find STAT3 Proteins for a variety of species such as anti-Human STAT3, anti-Rat STAT3, anti-Cow STAT3. The species listed below are among those available. Click on a link to go to the corresponding products.

STAT3 Proteins by Source

Here you will find STAT3 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

STAT3 Proteins by Protein Type

Here you can find STAT3 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

STAT3 Proteins by Application

Find STAT3 Proteins validated for a specific application such as WB, SDS, PC, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular STAT3 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

STAT3 Protein (AA 1-769) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1321594

Quantity 10 μg

Datasheet Datasheet

STAT3 Protein (AA 1-177) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7125094

Quantity 50 μg

Datasheet Datasheet

STAT3 Protein (AA 670-769) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1321596

Quantity 10 μg

Datasheet Datasheet

STAT3 Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7319035

Quantity 50 μg

Datasheet Datasheet

STAT3 Protein (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7579723

Quantity 100 μg

Datasheet Datasheet

STAT3 Protein (AA 346-552) (His tag)

Reactivity Cow, Human, Mouse, Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7417759

Quantity 100 μg

Datasheet Datasheet

STAT3 Protein (AA 335-546) (His tag)

Reactivity Cow, Human, Mouse, Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7417750

Quantity 100 μg

Datasheet Datasheet

STAT3 Protein (AA 135-279) (His tag)

Reactivity Cow, Human, Mouse, Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7417756

Quantity 100 μg

Datasheet Datasheet

STAT3 Protein (AA 656-768) (His tag,GST tag)

Reactivity Cow, Human, Mouse, Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7417762

Quantity 100 μg

Datasheet Datasheet

STAT3 Protein (AA 576-678) (His tag)

Reactivity Cow, Human, Mouse, Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7417753

Quantity 100 μg

Datasheet Datasheet

STAT3 Protein (AA 1-175) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1692021

Quantity 50 μg

Datasheet Datasheet

STAT3 Protein (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN7579722

Quantity 100 μg

Datasheet Datasheet

STAT3 Protein (AA 563-670) (His tag)

Reactivity Cow

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7401365

Quantity 100 μg

Datasheet Datasheet

STAT3 Protein (AA 656-768) (His tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7417423

Quantity 100 μg

Datasheet Datasheet

STAT3 Protein (GST tag)

Reactivity Human

Source Insect cells (Sf9)

Validations

Cat. No. ABIN6700517

Quantity 20 μg

Datasheet Datasheet

Latest Publications for our STAT3 Proteins

Li, Wu, Zeng, Zhang, Wang, Zhang, Lin: "ApoC1 promotes the metastasis of clear cell renal cell carcinoma via activation of STAT3." in: Oncogene, Vol. 39, Issue 39, pp. 6203-6217, (2021) (PubMed).

Zhu, Chang, Yan, Hu, Zeng, Zhou, Yuan, Ying, Cao, He, Yang: "AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer." in: Theranostics, Vol. 8, Issue 3, pp. 676-692, (2018) (PubMed).

Qian, Chai, Liang, Wang, Zhou, Xu, Zhang, Zhang, Si, Huang, Huang, Hong, Wang: "KIF5B-RET fusion kinase promotes cell growth by multilevel activation of STAT3 in lung cancer." in: Molecular cancer, Vol. 13, pp. 176, (2014) (PubMed).

Leung, Liu, Lin, Lu, Zhong, Susanti, Rao, Wang, Che, Chan, Leung, Chan, Ma: "Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening." in: Methods (San Diego, Calif.), Vol. 71, pp. 38-43, (2014) (PubMed).

Aliases for STAT3 Proteins

signal transducer and activator of transcription 3 (STAT3) Proteins
signal transduction and activation of transcription 3 (stat3) Proteins
signal transducer and activator of transcription 3 (stat3) Proteins
signal transducer and activator of transcription 3 (Stat3) Proteins
signal transducer and activator of transcription 3, gene 1 L homeolog (stat3.1.L) Proteins
signal transducer and activator of transcription 3 (acute-phase response factor) (stat3) Proteins
1110034C02Rik Proteins
Aprf Proteins
APRF Proteins
aprf Proteins
AW109958 Proteins
HIES Proteins
hies Proteins
stat3 Proteins
wu:fc15d02 Proteins
wu:fl59g06 Proteins
Xstat3 Proteins
z-Stat3 Proteins

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STAT3 Proteins by Origin

STAT3 Proteins by Source

STAT3 Proteins by Protein Type

STAT3 Proteins by Application

Popular STAT3 Proteins

Latest Publications for our STAT3 Proteins

Aliases for STAT3 Proteins

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