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- Target See all COL18A1 ELISA Kits
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
- Binding Specificity
- AA 1591-1774
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Reactivity
- Rat
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Application
- ELISA
- Purpose
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Rat Endostatin
- Brand
- PicoKine™
- Analytical Method
- Quantitative
- Specificity
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Expression system for standard: NSO
Immunogen sequence: H1591-K1774 - Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Collagen, Type XVIII, alpha 1 (COL18A1) ELISA Kit
COL18A1 Reactivity: Mouse Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
Collagen, Type XVIII, alpha 1 (COL18A1) ELISA KitCOL18A1 Reactivity: Human Colorimetric Sandwich ELISA 0.62 ng/mL - 40 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Collagen, Type XVIII, alpha 1 (COL18A1) ELISA KitCOL18A1 Reactivity: Rat Colorimetric Sandwich ELISA 31.25 pg/mL - 2000 pg/mL Plasma, Serum, Tissue Homogenate
Collagen, Type XVIII, alpha 1 (COL18A1) ELISA KitCOL18A1 Reactivity: Human Colorimetric Sandwich ELISA 0.63 ng/mL - 40 ng/mL Cell Culture Supernatant, Plasma, Serum
Collagen, Type XVIII, alpha 1 (COL18A1) ELISA KitCOL18A1 Reactivity: Human Colorimetric Competition ELISA 4.94 ng/mL - 400 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Collagen, Type XVIII, alpha 1 (COL18A1) ELISA KitWide Range COL18A1 Reactivity: Human Colorimetric Sandwich ELISA 6.25 ng/mL - 400 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Collagen, Type XVIII, alpha 1 (COL18A1) ELISA KitCOL18A1 Reactivity: Mouse Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
Collagen, Type XVIII, alpha 1 (COL18A1) ELISA KitCOL18A1 Reactivity: Rat Colorimetric Competition ELISA 1.23 ng/mL - 100 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Collagen, Type XVIII, alpha 1 (COL18A1) ELISA KitCOL18A1 Reactivity: Human AA 1154-1335 Colorimetric Sandwich ELISA 156-10000 pg/mL Cell Culture Supernatant, Milk, Plasma (EDTA), Plasma (heparin), Serum
Collagen, Type XVIII, alpha 1 (COL18A1) ELISA KitCOL18A1 Reactivity: Mouse AA 1591-1774 Colorimetric Sandwich ELISA 156-10.000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
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- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Expiry Date
- 12 months
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- Target See all COL18A1 ELISA Kits
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
- Alternative Name
- Endostatin (COL18A1 Products)
- Target Type
- Chemical
- Background
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Background: Endostatin is a naturally-occurring 20- kDa C-terminal fragment derived from type XVIII collagen. It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin. And It is produced by proteolytic cleavage of collagen XVIII, a member of the multiplexin family that is characterized by interruptions in the triple helix creating multiple domains, by proteases such as cathepsins. Using a genomic clone as a probe for fluorescence in situ hybridization, Endostatin was mapped the COL18A1 gene to 21q22.3. By immunoprecipitation analysis using membrane fractions of human mammary epithelial cells, It showed that endostatin specifically bound to cell surface nucleolin with high affinity. Blockage of nucleolin with neutralizing antibody or knockdown of nucleolin by RNA interference countered the antiendothelial activity of endostatin and abrogated its antiangiogenic and antitumor activity in vivo.
Synonyms: Collagen type XVIII, alpha (I) chain ,Col18a1 ,col18a1 ,
Full Gene Name: collagen, type XVIII, alpha 1
- UniProt
- Q9WUW5
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