COL18A1 Products
(Collagen, Type XVIII, alpha 1 (COL18A1))
Categories
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
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Featured COL18A1 Categories
COL18A1 Antibodies
High quality antibodies with extensive validation data.
COL18A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
COL18A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended COL18A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (3)
- (2)
Cat. No.
ABIN669951
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7445252
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN654663
Quantity
400 μL
Datasheet
Datasheet
Recommended COL18A1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
- (1)
Cat. No.
ABIN6954970
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
Cat. No.
ABIN6954969
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966496
Quantity
96 tests
Datasheet
Datasheet
Recommended COL18A1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7320492
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3078123
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3133944
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our COL18A1 products
: "Effect of Niacin on Inflammation and Angiogenesis in a Murine Model of Ulcerative Colitis." in: Scientific reports, Vol. 7, Issue 1, pp. 7139, (2019) (PubMed).: "Correlation of Plasma Vascular Endothelial Growth Factor and Endostatin Levels with Symptomatic Intra- and Extracranial Atherosclerotic Stenosis in a Chinese Han Population." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 26, Issue 5, pp. 1061-1070, (2017) (PubMed).
: "Impaired angiogenesis as a feature of digital ulcers in systemic sclerosis." in: Clinical rheumatology, Vol. 35, Issue 7, pp. 1743-51, (2016) (PubMed).
: "Endostatin is protective against monocrotaline-induced right heart disease through the inhibition of T-type Ca(2+) channel." in: Pflügers Archiv : European journal of physiology, Vol. 468, Issue 7, pp. 1259-70, (2016) (PubMed).
: "Treatment Interventions for Early Childhood Obesity: A Systematic Review." in: Academic pediatrics, Vol. 15, Issue 4, pp. 353-61, (2015) (PubMed).
: "ANGIOGENESIS INHIBITOR ENDOSTATIN PROTECTS MICE WITH SEPSIS FROM MULTIPLE ORGAN DYSFUNCTION SYNDROME." in: Shock (Augusta, Ga.), Vol. 44, Issue 4, pp. 357-64, (2015) (PubMed).
: "Stimulation of PAR-1 or PAR-4 promotes similar pattern of VEGF and endostatin release and pro-angiogenic responses mediated by human platelets." in: Platelets, Vol. 26, Issue 8, pp. 799-804, (2015) (PubMed).
: "Clinical significance of serum and tumor tissue endostatin evaluation in operable non-small cell lung cancer." in: Biomedical reports, Vol. 2, Issue 6, pp. 898-904, (2014) (PubMed).
: "Prognostic values of VEGF and endostatin with malignant pleural effusions in patients with lung cancer." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 15, Issue 19, pp. 8435-40, (2014) (PubMed).
: "A hypoxia-responsive glial cell-specific gene therapy vector for targeting retinal neovascularization." in: Investigative ophthalmology & visual science, Vol. 55, Issue 12, pp. 8044-53, (2014) (PubMed).
Synonyms and alternative names related to COL18A1
collagen type XVIII alpha 1 chain (COL18A1), collagen type XVIII alpha 1 chain a (col18a1a), collagen type XVIII alpha 1 chain (Col18a1), collagen, type XVIII, alpha 1 (COL18A1), collagen type XVIII alpha 1 (col18a1), collagen, type XVIII, alpha 1 (Col18a1), cb371, cb529, fc96d06, KNO, kno, KNO1, kno1, KS, sb:cb529, wu:fb47h10, wu:fb77g12, wu:fc50f04, wu:fc96d06, wu:fk02h12Protein level used designations for COL18A1
- antiangiogenic agent
- collagen alpha-1(XVIII) chain
- endostatin
- multi-functional protein MFP
- procollagen, type XVIII, alpha 1
- collagen, type XVIII, alpha 1
- alpha 1 type XVIII collagen
- collagen alpha-1(XVIII) chain-like
- LOW QUALITY PROTEIN: collagen alpha-1(XVIII) chain
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