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Browse our anti-CKAP5 (CKAP5) Antibodies

Full name:: anti-Cytoskeleton Associated Protein 5 Antibodies (CKAP5)

On www.antibodies-online.com are 27 Cytoskeleton Associated Protein 5 (CKAP5) Antibodies from 13 different suppliers available. A total of 27 CKAP5 products are currently listed.

Synonyms:: 3110043H24Rik, 4930432B04Rik, ch-TOG, CHTOG, CKAP5, ckap5b, D730027C18Rik, im:7143385, mKIAA0097, MSPS, T25636, TOG, TOGp, wu:fb14c01, wu:fb59e03, wu:fi33f02, xmap215, zgc:123012

list all antibodies	Gene Name	GeneID	UniProt
	CKAP5	9793	Q14008
	CKAP5	75786	A2AGT5
	CKAP5	311191
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M Phase

Top referenced anti-CKAP5 Antibodies

Human Polyclonal CKAP5 Primary Antibody for ICC, IF - ABIN152996 : Dionne, Sanchez, Compton: ch-TOGp is required for microtubule aster formation in a mammalian mitotic extract. in The Journal of biological chemistry 2000 (PubMed)
Show all 2 Pubmed References
Human Polyclonal CKAP5 Primary Antibody for IP, WB - ABIN438459 : Milunovic-Jevtic, Jevtic, Levy, Gatlin: In vivo mitotic spindle scaling can be modulated by changing the levels of a single protein: the microtubule polymerase XMAP215. in Molecular biology of the cell 2018 (PubMed)

More Antibodies against CKAP5 Interaction Partners

Xenopus laevis Cytoskeleton Associated Protein 5 (CKAP5) interaction partners

Results show that XMAP215 can be used as a handle to sense and mechanically manipulate the dynamics of the microtubule tip.
XMAP215 activity sets spindle length by controlling the total mass of spindle microtubules.

Human Cytoskeleton Associated Protein 5 (CKAP5) interaction partners

Eribulin binding to the tip of microtubules and subsequent loss of ch-TOG is a priming event leading to alterations in microtubule dynamics and breast cancer cell migration.
Data show that cytoskeleton associated protein 5 (chTOG) only weakly promotes importin-regulated microtubule nucleation, but acts synergistically with microtubule- associated protein TPX2.
Aurora-A kinase does not regulate TACC3-chTOG complex formation, indicating that Aurora-A solely functions as a recruitment factor for the TACC3-chTOG complex to centrosomes and proximal mitotic spindles.
Data show that five genes CKAP5, KPNB1, RAN, TPX2 and KIF11 were shown to be essential for tumor cell survival in both head and neck squamous cell carcinoma (HNSCC)and non-small cell lung cancer (NSCLC), but most particularly in HNSCC.
These observations indicate that EB1 and ch-TOG regulate microtubule organisation differently via distinct regions in the plus ends of microtubules.
Clathrin promotes centrosome maturation by stabilizing the microtubule-binding protein ch-TOG, defining a novel role for the clathrin-ch-TOG complex.
Data show that ILK performs its centrosome clustering activity in a centrosome-dependent, manner through the microtubule regulating proteins TACC3 and ch-TOG.
the association between aurora A phosphorylation and spindle apparatus; regulation from aurora A is mediated by CHC in recruiting phospho-TACC3 and subsequently ch-TOG to mitotic spindles.
Data show that 4-oxo-4-HPR inhibited tubulin polymerization and modulated gene expression of spindle aberration associated genes Kif 1C, Kif 2A, Eg5, Tara, tankyrase-1, centractin, and TOGp.
Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells
TOG has roles during mitosis in focusing MT minus ends at spindle poles, maintaining centrosome integrity, and contributing to spindle bipolarity
TOG mediates the association of hnRNP A2-positive granules with microtubules during transport and/or localization
Hsp90 is required to localize ch-TOG to the mitotic spindle.
A novel function of Aurora-A, the regulation of ch-TOG and MCAK localization, in a common pathway in control of spindle pole integrity.
ch-Tog has at least two distinct roles in spindle formation: it protects kinetochore microtubules from depolymerization by MCAK, and ch-Tog plays an essential role in centrosomal microtubule assembly, a function independent of MCAK activity.
Data hypothesize that TOGp is required for chromosome motility as a downstream consequence of reduced microtubule dynamics and/or density.

Mouse (Murine) Cytoskeleton Associated Protein 5 (CKAP5) interaction partners

our results demonstrate that CKAP5 is important in oocyte maturation and early embryo development, and CKAP5 might work together with CLTC in mouse oocyte maturation
in hippocampal neurons TOG is required for granule assembly, granule translation and synaptic plasticity, and affects behavior
Aurora-A kinase does not regulate TACC3-chTOG complex formation, indicating that Aurora-A solely functions as a recruitment factor for the TACC3-chTOG complex to centrosomes and proximal mitotic spindles.
ch-TOG promotes axonal development and is expressed in brain throughout development.

CKAP5 Antigen Profile

Antigen Summary

This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation\; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with CKAP5

cytoskeleton associated protein 5 (ckap5) antibody
cytoskeleton associated protein 5 S homeolog (ckap5.S) antibody
cytoskeleton associated protein 5 (CKAP5) antibody
cytoskeleton-associated protein 5 (LOC100548902) antibody
cytoskeleton associated protein 5 (Ckap5) antibody

3110043H24Rik antibody
4930432B04Rik antibody
ch-TOG antibody
CHTOG antibody
CKAP5 antibody
ckap5b antibody
D730027C18Rik antibody
im:7143385 antibody
mKIAA0097 antibody
MSPS antibody
T25636 antibody
TOG antibody
TOGp antibody
wu:fb14c01 antibody
wu:fb59e03 antibody
wu:fi33f02 antibody
xmap215 antibody
zgc:123012 antibody

Protein level used designations for CKAP5

cytoskeleton associated protein 5 , microtubule associated protein XMAP215 , cytoskeleton-associated protein 5 , microtubule-associated protein 215 , colonic and hepatic tumor over-expressed protein , Cytoskeleton-associated protein 5 , cytoskeleton-associated protein 5-like , colonic and hepatic tumor over-expressed gene protein , colonic and hepatic tumor overexpressed gene protein

GENE ID	SPECIES
398198	Xenopus laevis
398199	Xenopus laevis
423190	Gallus gallus
451160	Pan troglodytes
492614	Danio rerio
533980	Bos taurus
100011933	Monodelphis domestica
100050886	Equus caballus
100145713	Xenopus (Silurana) tropicalis
100379262	Anolis carolinensis
100379285	Gasterosteus aculeatus
100380854	Salmo salar
100473125	Ailuropoda melanoleuca
100548902	Meleagris gallopavo
9793	Homo sapiens
75786	Mus musculus
311191	Rattus norvegicus
100351133	Oryctolagus cuniculus
475986	Canis lupus familiaris

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Top referenced anti-CKAP5 Antibodies

More Antibodies against CKAP5 Interaction Partners

Xenopus laevis Cytoskeleton Associated Protein 5 (CKAP5) interaction partners

Human Cytoskeleton Associated Protein 5 (CKAP5) interaction partners

Mouse (Murine) Cytoskeleton Associated Protein 5 (CKAP5) interaction partners

CKAP5 Antigen Profile

Antigen Summary

Alternative names and synonyms associated with CKAP5

Protein level used designations for CKAP5

Show all anti-Cytoskeleton Associated Protein 5 (CKAP5) Antibodies with Pubmed References

Xenopus laevis Cytoskeleton Associated Protein 5 (CKAP5) interaction partners

Human Cytoskeleton Associated Protein 5 (CKAP5) interaction partners

Mouse (Murine) Cytoskeleton Associated Protein 5 (CKAP5) interaction partners

Antigen Summary

Alternative names and synonyms associated with CKAP5

Protein level used designations for CKAP5