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anti-Human CKAP5 Antibodies:
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Human Polyclonal CKAP5 Primary Antibody for ICC, IF - ABIN152996
Dionne, Sanchez, Compton: ch-TOGp is required for microtubule aster formation in a mammalian mitotic extract. in The Journal of biological chemistry 2000
Show all 2 Pubmed References
This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation\; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.
cytoskeleton associated protein 5
, microtubule associated protein XMAP215
, cytoskeleton-associated protein 5
, microtubule-associated protein 215
, colonic and hepatic tumor over-expressed protein
, Cytoskeleton-associated protein 5
, cytoskeleton-associated protein 5-like
, colonic and hepatic tumor over-expressed gene protein
, colonic and hepatic tumor overexpressed gene protein