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Browse our anti-Dynamitin (DCTN2) Antibodies

Full name:: anti-Dynactin 2 (p50) Antibodies (DCTN2)

On www.antibodies-online.com are 102 Dynactin 2 (p50) (DCTN2) Antibodies from 20 different suppliers available. Additionally we are shipping Dynamitin Proteins (16) and Dynamitin Kits (3) and many more products for this protein. A total of 127 Dynamitin products are currently listed.

Synonyms:: 2310042E05Rik, C87049, C130077D06Rik, CG8269, DCTN-50, dctn2, DCTN50, dDyn, Dmel\\CG8269, dmn, dyna, DYNAMITIN, GMP23-48K, l(2)k16109, l(2)k16218, p50, p50/Dmn, p50/dynamitin, RBP50, zgc:63867

list all antibodies	Gene Name	GeneID	UniProt
	DCTN2	69654	Q99KJ8
	DCTN2	10540	Q13561
	DCTN2	299850	Q6AYH5
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Most Popular Reactivities for anti-Dynamitin (DCTN2) Antibodies

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anti-Mouse (Murine) Dynamitin Antibodies:

anti-Human Dynamitin Antibodies:

anti-Rat (Rattus) Dynamitin Antibodies:

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Top referenced anti-Dynamitin Antibodies

Human Polyclonal Dynamitin Primary Antibody for IF, WB - ABIN523956 : Chatin, Colombier, Gamblin, Allouis, Le Bouffant: Dynamitin affects cell-surface expression of voltage-gated sodium channel Nav1.5. in The Biochemical journal 2014 (PubMed)
Human Polyclonal Dynamitin Primary Antibody for ICC, IF - ABIN4306494 : Morris, Assi, Salh, Dedhar: Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum. in Scientific reports 2015 (PubMed)
Human Polyclonal Dynamitin Primary Antibody for ICC, IF - ABIN4306496 : Ayyadevara, Balasubramaniam, Parcon, Barger, Griffin, Alla, Tackett, Mackintosh, Petricoin, Zhou, Shmookler Reis: Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls. in Aging cell 2016 (PubMed)

More Antibodies against Dynamitin Interaction Partners

Fruit Fly (Drosophila melanogaster) Dynactin 2 (p50) (DCTN2) interaction partners

Dmn may play an important role in Drosophila spermiogenesis by affecting transport of many important cytoplasmic materials.
Our results suggest a model whereby endocytic activity recruits Dynein to the oocyte cortex. The motor along with its regulators, Dynactin and Lis1, functions to ensure efficient endocytic uptake and maturation.

Mouse (Murine) Dynactin 2 (p50) (DCTN2) interaction partners

Altered levels of Cep135 and p50 by RNAi and protein overexpression caused the release of endogenous partner molecules from centrosomes.

Human Dynactin 2 (p50) (DCTN2) interaction partners

This is the first time a haplotype on chromosome 12 containing sequence variants in the genes DCTN2, DNAH10, LRIG3, and MYO1A has been linked to an inherited neuropathy in humans.
dynamitin is involved in the regulation of Nav1.5 cell-surface density
the determinants of p50/DM required for self-oligomerization of the protein and for interactions with other subunits of the dynactin complex
Altered levels of Cep135 and p50 by RNAi and protein overexpression caused the release of endogenous partner molecules from centrosomes.
the Sec23p component of the COPII complex directly interacts with the dynactin complex through the carboxy-terminal cargo-binding domain of p150(Glued).
DCTN2 is required in the earliest stages of peroxisome biogenesis.
study does not support a major role for DCTN2 overexpression in carcinogenesis
Data show how dynamitin's different structural domains contribute to its ability to self-associate, interact with dynactin and assemble into a complex with its close binding partner, p24.
The interaction between ZW10 and dynamitin showed that the N-terminal region of ZW10 is the major binding site for dynamitin and, like full-length ZW10, could move along microtubules to the centrosomal area in a dynein-dynactin-dependent manner.

Zebrafish Dynactin 2 (p50) (DCTN2) interaction partners

These results indicate that the p50 component of the dynactin complex is essential for the survival of sensory neurons and the maintenance of ganglion cell axons, and functions as a major determinant of apicobasal polarity in retinal radial glia.

Dynamitin (DCTN2) Antigen Profile

Antigen Summary

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with Dynamitin (DCTN2)

dynactin subunit 2 (DCTN2) antibody
dynactin subunit 2 S homeolog (dctn2.S) antibody
Dynactin 2, p50 subunit (DCTN2-p50) antibody
dynactin subunit 2 (dctn2) antibody
dynactin 2 (Dctn2) antibody
dynactin subunit 2 (Dctn2) antibody
dynactin 2 (p50) (dctn2) antibody
dynactin subunit 2 L homeolog (dctn2.L) antibody

2310042E05Rik antibody
C87049 antibody
C130077D06Rik antibody
CG8269 antibody
DCTN-50 antibody
dctn2 antibody
DCTN50 antibody
dDyn antibody
Dmel\\CG8269 antibody
dmn antibody
dyna antibody
DYNAMITIN antibody
GMP23-48K antibody
l(2)k16109 antibody
l(2)k16218 antibody
p50 antibody
p50/Dmn antibody
p50/dynamitin antibody
RBP50 antibody
zgc:63867 antibody

Protein level used designations for DCTN2

dynactin 2 (p50) , dynactin subunit 2 , dynactin subunit 2-B , dynamitin , CG8269-PA , Dmn-PA , p50-dynamitin , p50 dynamitin , p50/Dynamitin , 50 kDa dynein-associated polypeptide , dynactin complex 50 kDa subunit , growth cone membrane protein 23-48K , 50 kD dynein-associated polypeptide , dynactin complex 50 kD subunit , p50/dynamitin , dynactin subunit 2-A

GENE ID	SPECIES
100050464	Equus caballus
100171591	Pongo abelii
380299	Xenopus laevis
44086	Drosophila melanogaster
548423	Xenopus (Silurana) tropicalis
714948	Macaca mulatta
100339187	Oryctolagus cuniculus
100615725	Pan troglodytes
69654	Mus musculus
10540	Homo sapiens
299850	Rattus norvegicus
394141	Danio rerio
447510	Xenopus laevis
395587	Gallus gallus
474415	Canis lupus familiaris
527201	Bos taurus

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Show all anti-Dynactin 2 (p50) (DCTN2) Antibodies with Pubmed References