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anti-Mouse (Murine) Dynamitin Antibodies:
anti-Human Dynamitin Antibodies:
anti-Rat (Rattus) Dynamitin Antibodies:
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Human Polyclonal Dynamitin Primary Antibody for IF, WB - ABIN523956
Chatin, Colombier, Gamblin, Allouis, Le Bouffant: Dynamitin affects cell-surface expression of voltage-gated sodium channel Nav1.5. in The Biochemical journal 2014
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
dynactin 2 (p50)
, dynactin subunit 2
, dynactin subunit 2-B
, p50 dynamitin
, 50 kDa dynein-associated polypeptide
, dynactin complex 50 kDa subunit
, growth cone membrane protein 23-48K
, 50 kD dynein-associated polypeptide
, dynactin complex 50 kD subunit
, dynactin subunit 2-A