Browse our anti-Caveolin-1 (CAV1) Antibodies

Zebrafish Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

1. These results point to intestinal epithelial cell CAV1 as a potential therapeutic target to lower circulating free fatty acids and LDL cholesterol.

2. Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration.

3. The development of transgenic zebrafish lines expressing CLTA (show CLTA Antibodies) fused to dsRed and CAV1 fused to GFP is reported.

4. maternally expressed zebrafish Cav-1 regulates dorsoventral patterning by limiting nuclear translocation of active beta-catenin (show CTNNB1 Antibodies)

5. These results support important and previously unanticipated roles for the Caveolin-1 isoforms in vertebrate organogenesis.

Xenopus laevis Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

1. interactions of cav1 at lipid-exposed domains regulate the partition of the receptor into membrane raft microdomains

Mouse (Murine) Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

1. The part of PKC regulation of CaV1.2 in the heart involves changes in channel's cellular fate. The mechanism of this PKC regulation appears to involve the C-terminus of alpha1C, possibly corroborating the previously proposed role of NT-CT interactions within alpha1C.

2. Findings suggest that CAV1 might be involved in apoptosis and proliferation regulation in pancreatic beta cells.

3. Caveolin1 is required for Th1 (show HAND1 Antibodies) cell infiltration, but not tight junction remodeling at the Blood-Brain Barrier in autoimmune neuroinflammation

4. Results suggest distinct functional roles for type 1 ryanodine receptor (RYR1 (show RYR1 Antibodies)) and Ca2 (show CA2 Antibodies)+ channels-the 1,4-dihydropyridine receptor (Cav1.1 (show CACNA1S Antibodies)) in skeletal primary and secondary myogenesis.

5. genetic deletion of Cav-1 exacerbated and cavtratin administration inhibited choroidal and retinal neovascularization

6. findings suggest that HMGB1 (show HMGB1 Antibodies) induces the transcytosis of albumin (show ALB Antibodies) via RAGE (show AGER Antibodies)-dependent Src (show SRC Antibodies) phosphorylation and Cav-1 phosphorylation. These studies revealed a new mechanism of HMGB1 (show HMGB1 Antibodies)-induced endothelial hyperpermeability.

7. caveolin-1 (Cav-1) participates in intraocular pressure maintenance via modulation of aqueous humor drainage from the eye.

8. DJ-1 (show PARK7 Antibodies) has a role in glutamate (show GRIN1 Antibodies) uptake into astrocytes by regulating flotillin-1 (show FLOT1 Antibodies) and caveolin-1 expression

9. These results suggest that the phosphorylated CAV1 functions to activate autophagy through binding to the BECN1 (show BECN1 Antibodies)/VPS34 (show PIK3C3 Antibodies) complex under oxidative stress and to protect against ischemic damage.

10. The effects of ouabain on contractility between WT and cav-1 KO mice were not significantly different.

Human Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

1. down-regulation of Cav-1 may aggravate DNA damage of Chang liver cells through reducing the interaction of Cav-1 and Mdm2 (show MDM2 Antibodies), which results in the promotion of p53 (show TP53 Antibodies) degradation.

2. High CAV1 expression is associated with Small Cell Lung Cancer.

3. NEDD8 (show NEDD8 Antibodies) seems to inhibit the Src (show SRC Antibodies)-mediated phosphorylation of caveolin-1 by modifying the structure of caveolin-1 protein, which blocks the migration of cancer cells. Although the neddylation process is currently regarded as an emerging target for cancer therapy, our results suggest the possibility that the inhibition of neddylation could facilitate cancer invasion or metastasis at least in some types of cancers.

4. High CAV1 expression is associated with Aggressive Behaviour of Breast Cancer.

5. Cav1 and PY14Cav1 were positively correlated with ESCC lymphatic metastasis and cancer stages. Rho/ROCK pathway activation promoted ESCC metastasis by regulating Cav1.

6. we revisited the question of the relationship between Cav1 and Stat3 (show STAT3 Antibodies)-ptyr705 in non-transformed mouse fibroblasts and in human lung carcinoma cells, by examining their effect at different cell densities.Our results demonstrate that Cav1 downregulates cadherin-11, by a mechanism which requires the Cav1 scaffolding domain. This cadherin-11 downregulation, leads to a reduction in cRac1 and Stat3 (show STAT3 Antibodies) activity levels.

7. Cav-1 acts as a positive or negative regulator of tumor cell growth via the reciprocal control for the RAF (show RAF1 Antibodies)-ERK (show EPHB2 Antibodies) feedback loop, and the mitogenic switch of Cav-1 function is tightly linked to bidirectional alteration of its expression in tumor progression.

8. This is the first demonstration of caveolin-1 expression in human primary uveal melanoma cell lines and observation that the origin of cells (uveal/cutaneous) has an impact when considering the utility of caveolin-I as a melanoma cell marker.

9. Together, these results suggest that CAV1 protects host cells against Group A Streptococcus invasion by a caveola-independent mechanism.

10. CAV-1 is commonly downregulated in patients with primary CRC (show CALR Antibodies), which suggests its tumor suppressor role in early stages of this disease.

Pig (Porcine) Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

1. Caveolin-1 is a modulator of fibroblast activation and a potential biomarker for gastric cancer

2. transcription factor Sp1 (show SP1 Antibodies) interacts with nucleotides -123/-114, indicating that Sp1 (show SP1 Antibodies) could play a key role in the transcriptional regulation of pig CAV-1

3. Two alternative transcript variants encode two isoforms, caveolin-1-alpha and -beta; Cav1 may be implicated in pathogenesis of Glasser's disease of swine.

4. The plasma membrane Na/K-ATPase (show ATP1A1 Antibodies)-caveolin-1 interaction may represent an important sensing mechanism by which the cells regulate the sterol regulatory element-binding protein (show CNBP Antibodies) pathway.

5. The present study indicates that caveolin-containing rafts/caveolins such as caveolin-1 could play a modulating role during oligodendroglial differentiation and regeneration via NGF (show NGFB Antibodies)/TrkA (show NTRK1 Antibodies) signaling.

6. Cav-1 might be a candidate gene for carcass traits, and might provide valuable information for understanding the mechanism of caveolae signaling in fat deposition by using the animal model of pig

Rabbit Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

1. Caveolin-1 expression ameliorates nephrotic damage in a rabbit model of cholesterol-induced hypercholesterolemia.

2. 8-Bromo-cAMP stimulated alpha-methyl-D-glucopyranoside uptake via Epac and PKA-dependent SGLTs expression and trafficking through cav-1 and F-actin in proximal tubule cells.

Cow (Bovine) Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

1. Caveolin-1 scaffolding domain residue phenylalanine 92 modulates Akt (show AKT1 Antibodies) signaling

2. Data show that resveratrol (Res) reversed caveolin-1 (Cav-1)/endothelial nitric oxide synthase (eNOS (show NOS3 Antibodies)) expressions in high glucose cultured bovine aortic endothelial cells (BAECs).

3. these data provide the first detailed analysis of Cav-1 binding to one of its most significant client proteins, eNOS (show NOS3 Antibodies).

4. Study identifies a critical role of caveolin-1 in the regulation of eNOS (show NOS3 Antibodies) uncoupling via a biopterin-dependent mechanism.

5. Data indicate that caveolin-1 expression is required for insulin (show INS Antibodies) uptake by aortic endothelial cells.

6. caveolin-1 is not required for the targeting of signaling molecules to caveolae/lipid rafts

7. integrin activation with shear stress results in SFK-regulated caveolin-1 phosphorylation that, in turn, mediates Csk (show CSK Antibodies) association at integrin sites, where it plays a role in downstream, shear-stimulated myelin light chain diphosphorylation.

8. importance of CAV1 amino acids 89-95 and particularly F92 in mediating eNOS (show NOS3 Antibodies) inhibition by AP-Cav and Cav-1

9. When endothelial cells were exposed to shear stress, caveolin-1 was transiently dephosphorylated.

10. caveolin-1 tyrosine 14 phosphorylation has a role in cell adhesion and migration

Guinea Pig Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

1. results suggest that cell division control protein 42(CDC42 (show CDC42 Antibodies)) activation is favored by the disruption of the caveolin-1-CDC42 (show CDC42 Antibodies) interaction, allowing for its participation in the regulation of capacitation and the acrosome reaction

Caenorhabditis elegans (C. elegans) Caveolin 1, Caveolae Protein, 22kDa (CAV1) interaction partners

1. The distribution of CAV-1 is highly dynamic during development and provides new insights into the sorting mechanisms that regulate CAV-1 localization.