anti-Dog (Canine) MXI1 antibody for ELISA

Recommended MXI1 Antibody (supplied by: Log in to see )

Antigen
MAX Interactor 1 (MXI1) Antibodies
  • mxi
  • mad2
  • mxd2
  • xmxi1
  • MGC89544
  • MXI1
  • etID309773.22
  • fb16b12
  • fb55f03
  • wu:fb16b12
  • wu:fb55f03
  • wu:fd06a08
  • wu:fz74f10
  • ENSMUSG00000067085
  • Gm10197
  • Mad2
  • bHLHc11
  • MXI-WR
  • MAD2
  • MXD2
  • MXI
  • MAX interactor 1, dimerization protein
  • max interactor 1, dimerization protein
  • MAX interactor 1, dimerization protein L homeolog
  • mxi1
  • MXI1
  • Mxi1
  • mxi1.L
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
44
37
15
5
5
5
4
4
3
2
2
2
2
2
1
Host
Rabbit
47
10
3
Clonality
Polyclonal
Conjugate
This MXI1 antibody is un-conjugated
3
3
3
2
2
2
Application
ELISA, Western Blotting (WB)
52
27
7
5
3
3
2
1
1
1
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Available images

Catalog No. ABIN2460213
$ 446.88
Plus shipping costs $45.00

General

Antigen MAX Interactor 1 (MXI1) Antibodies
Reactivity Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(44), (37), (15), (5), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1)
Host Rabbit
(47), (10), (3)
Clonality
Polyclonal
Conjugate This MXI1 antibody is un-conjugated
(3), (3), (3), (2), (2), (2)
Application ELISA, Western Blotting (WB)
(52), (27), (7), (5), (3), (3), (2), (1), (1), (1)
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Product Details anti-MXI1 Antibody

Target Details MXI1 Application Details Handling Images
Purification Antibody is purified by peptide affinity chromatography method.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MXI1.
Plasmids, Primers & others

Target Details MXI1

Product Details anti-MXI1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MXI1 (MXI1 Antibody Abstract)
Background Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The MXI1 gene encodes a transcriptional repressor protein thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in MXI1 are frequently found in patients with prostate tumors.Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
Molecular Weight 26 kDa, 21 kDa, 33 kDa
Gene ID 4601
NCBI Accession NP_005953
UniProt P50539
Pathways Maintenance of Protein Location

Application Details

Product Details anti-MXI1 Antibody Target Details MXI1 Handling Images back to top
Application Notes MXI1 antibody can be used for detection of MXI1 by ELISA at 1:312500. MXI1 antibody can be used for detection of MXI1 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions For Research Use only

Handling

Product Details anti-MXI1 Antibody Target Details MXI1 Application Details Images back to top
Format Lyophilized
Reconstitution Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration 1 mg/mL
Buffer Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handling Advice As with any antibody avoid repeat freeze-thaw cycles.
Storage 4 °C/-20 °C
Storage Comment For short periods of storage (days) store at 4 °C. For longer periods of storage, store MXI1 antibody at -20 °C.

Images

Product Details anti-MXI1 Antibody Target Details MXI1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-MAX Interactor 1 (MXI1) antibody (ABIN2460213) anti-MAX Interactor 1 (MXI1) antibody