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anti-Human BCL2 Antibodies:
anti-Rat (Rattus) BCL2 Antibodies:
anti-Mouse (Murine) BCL2 Antibodies:
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Human Monoclonal BCL2 Primary Antibody for ICC, IHC (fro) - ABIN3044481
Jiang, Li, Zhou, Wang, Zhang, Wang: Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways. in International journal of molecular medicine 2014
Show all 91 Pubmed References
Human Polyclonal BCL2 Primary Antibody for ELISA, WB - ABIN3042814
Zong, Li, Lin, Hou, Ma: Lipoxin A4 pretreatment mitigates skeletal muscle ischemia-reperfusion injury in rats. in American journal of translational research 2017
Show all 79 Pubmed References
Human Polyclonal BCL2 Primary Antibody for IF, IHC (p) - ABIN388095
Zheng, Zhou, Ye, Li, Bai, Zhang: The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells. in World journal of surgical oncology 2010
Show all 19 Pubmed References
Human Monoclonal BCL2 Primary Antibody for IHC (fro), FACS - ABIN967312
Batistatou, Merry, Korsmeyer, Greene: Bcl-2 affects survival but not neuronal differentiation of PC12 cells. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1993
Show all 13 Pubmed References
Mouse (Murine) Monoclonal BCL2 Primary Antibody for FM, IHC (fro) - ABIN967441
Hockenbery, Nuñez, Milliman, Schreiber, Korsmeyer: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. in Nature 1991
Show all 10 Pubmed References
Human Monoclonal BCL2 Primary Antibody for IHC (f), IHC (fro) - ABIN967322
Krajewski, Tanaka, Takayama, Schibler, Fenton, Reed: Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. in Cancer research 1993
Show all 7 Pubmed References
Human Monoclonal BCL2 Primary Antibody for IHC (f), IHC (fro) - ABIN967321
Pezzella, Jones, Ralfkiaer, Ersbøll, Gatter, Mason: Evaluation of bcl-2 protein expression and 14;18 translocation as prognostic markers in follicular lymphoma. in British journal of cancer 1992
Show all 7 Pubmed References
Dog (Canine) Polyclonal BCL2 Primary Antibody for IHC, IHC (p) - ABIN4283360
Chopra, Ray, Dwivedi, Tiwari, Singh, Singh, Kushwaha, Jahan, Pandey, Gupta, Chaturvedi, Pant, Ray, Gupta: Photoprotective efficiency of PLGA-curcumin nanoparticles versus curcumin through the involvement of ERK/AKT pathway under ambient UV-R exposure in HaCaT cell line. in Biomaterials 2016
Show all 6 Pubmed References
Human Polyclonal BCL2 Primary Antibody for IF (p), IHC (p) - ABIN707156
Wang, Ma, Su: NF-?B pathway contributes to cadmium-induced apoptosis of porcine granulosa cells. in Biological trace element research 2013
Show all 6 Pubmed References
Human Monoclonal BCL2 Primary Antibody for FACS, ICC - ABIN638444
Soilu-Hänninen, Ekert, Bucci, Syroid, Bartlett, Kilpatrick: Nerve growth factor signaling through p75 induces apoptosis in Schwann cells via a Bcl-2-independent pathway. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1999
Show all 5 Pubmed References
The BAK1 (show BAK1 Antibodies)/BCL2 ratio was positively correlated with the results of audiometric tests. Our results indicate that BAK (show BAK1 Antibodies)-mediated apoptosis may be a core mechanism in the progression of age-related hearing impairment in humans
A decrease in miR (show MLXIP Antibodies)-184 level by E6 oncoprotein may predict unfavorable response to cisplatin-based chemotherapy in HPV-infected non-small cell lung carcinoma patients via increasing Bcl-2 expression.
these findings confirm that over-expression of BCL2 and MYC (show MYC Antibodies) proteins by IHC in DLBCL is associated with a poor prognosis in R-CHOP (show DDIT3 Antibodies)-treated patients.
dose-intensified immunochemotherapy with or without HDC (show HDC Antibodies)/ASCT was not effective in patients with de novo DLBCL, who had advanced disease and concurrent overexpression of MYC (show MYC Antibodies) and BCL2 protein.
These results suggested together that tBHQ could ameliorate arsenic-induced cytotoxicity and apoptosis, which might be linked with the induction of Nrf2 (show GABPA Antibodies)-dependent antioxidant responses as well as stabilization of anti-apoptotic factor Bcl-2 in human keratinocytes.
There were higher expressions of XIAP (show XIAP Antibodies) (p = 0.0032) and Bcl-2 (p = 0.0351) in the glioblastoma samples compared to the control samples of normal brain. These results raise the question of whether Bcl-2 and XIAP (show XIAP Antibodies) genes can be responsible for the inhibition of programmed cell death in glioblastomas.
These findings uncover a novel mechanism through which mitochondrial PKM2 phosphorylates Bcl2 and inhibits apoptosis directly.
Study reveals a previously unrecognized synergism between ETV6 (show ETV6 Antibodies)/RUNX1 (show RUNX1 Antibodies) and BCL2 impacting on malignant disease and autoimmunity.
beta-asarone changed the cellular morphology, inhibited cell proliferation, and enhanced the expression of P53 (show TP53 Antibodies), LC3 (show MAP1LC3A Antibodies)-II/I, Beclin-1 (show BECN1 Antibodies), AMPK (show PRKAA1 Antibodies), and pAMPK while inhibiting the expression of P62 (show GTF2H1 Antibodies), Bcl-2, mTOR (show FRAP1 Antibodies), and pmTOR in glioma cells.
anti-apoptotic molecules BclxL (show BCL2L1 Antibodies) and Bcl-2 and the pro-apoptotic factors BAD and BID (show BID Antibodies) cooperate to promote migration of triple-negative breast cancer cells stimulated with cl-CD95L (show FASL Antibodies).
Bcl2 is the autophagy-related target of miR (show MLXIP Antibodies)-449a.
Acute ethanol exposure induced autophagy-mediated heart toxicity and injury mainly through the ROS (show ROS1 Antibodies)-JNK (show MAPK8 Antibodies)-Bcl-2 signaling pathway.
Th17 cells are resistant to glucocorticoid-induced apoptosis and cytokine suppression, at least in part due to high levels of BCL-2. These findings support a role of Th17 cells in glucocorticoid-resistant inflammatory conditions such as certain endotypes of asthma.
E2 protects skeletal myoblasts against apoptosis induced by H2 O2 modulating p53 (show TP53 Antibodies) and FoxO (show FOXO3 Antibodies) transcription factors and then their target genes Bcl-2, Bim (show BCL2L11 Antibodies), Puma (show BBC3 Antibodies), PERP (show PERP Antibodies), and MDM2 (show MDM2 Antibodies), without affecting Noxa (show PMAIP1 Antibodies) gene.
Bcl-2 expression has a significant impact on the mineralogical content of enamel crystals of tooth structure
The results suggest that CARP (show ANKRD1 Antibodies) can protect against hypoxia-reperfusion induced cardiomyocyte apoptosis, possibly through increasing anti-apoptosis Bcl2 gene expression.
This study provides evidence from transgenic mouse models that Crebbp (show CREBBP Antibodies) deletion results in deficits in B-cell development and can cooperate with Bcl2 overexpression to promote B-cell lymphoma.
an essential role for the binding of BCL2 to BIM (show BCL2L11 Antibodies) in the survival of noncycling NK cells.
LIGHT signalling pathway combined with IFN-gamma (show IFNG Antibodies) induces beta cells apoptosis via an NF-kappaB (show NFKB1 Antibodies)/Bcl2-dependent mitochondrial pathway.
These results suggest a role for mitochondrial p53 (show TP53 Antibodies) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax (show BAX Antibodies) and Bcl2.
Zebrafish gene expressions of P53 (show TP53 Antibodies), Bcl-2, Bax (show BAX Antibodies) and caspase-3 (show CASP3 Antibodies) were elevated after exposure with microcystin-LR under different ambient temperatures.
Analysis using clinical biopsy specimens revealed autophagy and increased levels of BCL2, S1P1 (show S1PR1 Antibodies), and ICAM1 (show ICAM1 Antibodies) in human T-lymphoblastic lymphoma compared with T-lymphoblastic leukemia.
Real-time RT-PCR revealed acetaminophen treatment of zebrafish embryos decreased the expression of cox2 (show COX2 Antibodies) and bcl2, but increased p53 (show TP53 Antibodies) expression.
Leukemia onset was dramatically accelerated in transgenic fish overexpressing human Notch1 (show NOTCH1 Antibodies) and fish bcl-2, indicating synergy between the Notch (show NOTCH1 Antibodies) pathway and the bcl2-mediated antiapoptotic pathway.
Over-expression of STC-1 (show STC1 Antibodies) up-regulated Bcl-2 protein expression and slightly down-regulated caspase-3 (show CASP3 Antibodies) production in the damaged cells. Findings from this study suggest that STC-1 (show STC1 Antibodies) plays a protective role in intestinal cells through an antioxidant mechanism.
BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax (show BAX Antibodies) expression.
G3139, a BCL-2 antisesnse oligonucleotide is a promising candidate for treatment of patients with imatinib-resistant Ph-positive leukemia.
role of vascular endothelial growth factor receptor-1 (show FLT1 Antibodies) in Bcl-2 expression
apoptosis-inducing factor (show AIFM1 Antibodies) was expressed in luminal alveolar cells and, in concert with a change in bax (show BAX Antibodies) protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses
mRNA expression of Bax (show BAX Antibodies), Bcl-2, caspase-3 (show CASP3 Antibodies) and-7 cannot be used as a reliable apoptosis detection method.
These results propose an additional mechanism whereby resveratrol may exert its cardioprotective effects and suggest a key role for Bcl-2 in the resveratrol anti-apoptotic action, especially in disrupting peroxynitrite-triggered mitochondrial pathway.
bcl-2 and bax (show BAX Antibodies) were expressed strongly in denervated guinea-pig facial muscle. [bcl-2; bax (show BAX Antibodies)]
excessive apoptosis does occur in acetabular cartilage with developmental dislocations of the hip, and is positively correlated with high caspase-3 (show CASP3 Antibodies) expression as well as low Bcl-2 expression.
These results indicate that RI-PostC can ameliorate myocardial ischemia-reperfusion injury and increase the Bcl-2/Bax (show BAX Antibodies) ratio through a mechanism involving protein kinase C (show PKC Antibodies).
Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax (show BAX Antibodies) and decreasing expression of bcl2.
Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 and increased expression of Bax (show BAX Antibodies).
Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 (show TP53 Antibodies) and decrease in the antiapoptotic BCl2 proteins.
Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 and down-regulating the activation of caspase-3 (show CASP3 Antibodies).
Data show that the damaged electron transport chain leads to bcl-2 depletion and MPT opening.
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
apoptosis regulator Bcl-2
, protein phosphatase 1, regulatory subunit 50
, B cell lymphoma 2 associated oncogene
, B-cell leukemia/lymphoma 2
, Bcl2-like protein
, BCL2B-cell CLL/lymphoma 2
, B-cell lymphoma protein 2
, B-cell CLL/lymphoma 2
, LOW QUALITY PROTEIN: apoptosis regulator Bcl-2
, Apoptosis regulator Bcl-2