RPS6KA5 Proteins

10 Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) Proteins from 6 manufacturers are available on www.antibodies-online.com.

Data Quality
  • 7
Type
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    Protein
Antigen
  • 10
Reactivity
  • 9
  • 1
Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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Biological Activity
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10 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3136336
$13,376.85
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 70 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3093500
$13,376.85
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 70 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2731176
$932.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
ReactivityHuman
Application AP, AA, KAA, ELISA, WB
Order details Cat. No. ABIN1318830
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1318832
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1318834
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2731177
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Insect Cells (Source), Purity 70 % - 90 %
ReactivityHuman
Application Func
Order details Cat. No. ABIN5509024
$340.00
10 μg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application Imm, PC, SDS, WB
Order details Cat. No. ABIN5665179
$560.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source)
ReactivityHuman
Application SDS, WB
Order details Cat. No. ABIN6120647
$590.93
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
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RPS6KA5 Protein Profile

Protein Summary

Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression. In skeletal myoblasts is required for phosphorylation of RELA at 'Ser-276' during oxidative stress. In erythropoietin-stimulated cells, is necessary for the 'Ser-727' phosphorylation of STAT3 and regulation of its transcriptional potential. Phosphorylates ETV1/ER81 at 'Ser-191' and 'Ser-216', and thereby regulates its ability to stimulate transcription, which may be important during development and breast tumor formation. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and EGF, which results in the transcriptional activation of several immediate early genes, including proto- oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 1 (HMGN1/HMG14). In lipopolysaccharide-stimulated primary macrophages, acts downstream of the Toll-like receptor TLR4 to limit the production of pro- inflammatory cytokines. Functions probably by inducing transcription of the MAP kinase phosphatase DUSP1 and the anti- inflammatory cytokine interleukin 10 (IL10), via CREB1 and ATF1 transcription factors. Plays a role in neuronal cell death by mediating the downstream effects of excitotoxic injury.

Alternative names and synonyms associated with RPS6KA5

  • ribosomal protein S6 kinase A5 (RPS6KA5) antibody
  • ribosomal protein S6 kinase, polypeptide 5 (Rps6ka5) antibody
  • ribosomal protein S6 kinase A5 (Rps6ka5) antibody
  • 3110005L17Rik antibody
  • 6330404E13Rik antibody
  • AI854034 antibody
  • Msk1 antibody
  • MSPK1 antibody
  • RLPK antibody

Protein level used designations for RPS6KA5

90 kDa ribosomal protein S6 kinase 5 , RSK-like protein kinase , RSKL , S6K-alpha-5 , nuclear mitogen- and stress-activated protein kinase 1 , ribosomal protein S6 kinase alpha-5 , mitogen- and stress-activated protein kinase-1 , ribosomal protein S6 kinase, polypeptide 5 , RLSK , mitogen and stress-activated protein kinase 1 , ribosomal protein S6 kinase, 90kDa, polypeptide 5

GENE ID SPECIES
9252 Homo sapiens
504408 Bos taurus
423408 Gallus gallus
73086 Mus musculus
314384 Rattus norvegicus
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