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Here, the authors report that centrioles in delta-tubulin and epsilon-tubulin null mutant human cells lack triplet microtubules and fail to undergo centriole maturation.
our data suggest that TUBD1 mRNA isoform expression profile in peripheral blood could be an accessible biomarker for predicting the risk for diabetic retinopathy development.
Loss-of-function mutations in Tubd1 prevent cells from assembling primary cilia and consequently lead to the failure to respond to Hedgehog ligands.
In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head (By similarity).
tubulin, delta 1
, delta tubulin
, tubulin delta chain