ABCC8 ELISA Kits
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ABCC8 ELISA Kit (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8) ELISA Kit
ABCC8 Antigen Profile
Protein Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed\; however, the transcript variants have not been fully described.
Alternative names and synonyms associated with ABCC8
- ATP binding cassette subfamily C member 8 (ABCC8) antibody
- ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8) antibody
- ATP binding cassette subfamily C member 8 (Abcc8) antibody
- ABC36 antibody
- D930031B21Rik antibody
- HHF1 antibody
- HI antibody
- HRINS antibody
- MRP8 antibody
- PHHI antibody
- Sur antibody
- Sur1 antibody
- SUR1delta2 antibody
- TNDM2 antibody
Protein level used designations for ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8 , ATP-binding cassette, sub-family C, member 8 , ATP-binding cassette sub-family C member 8 , ATP-binding cassette transporter sub-family C member 8 , sulfonylurea receptor (hyperinsulinemia) , sulfonylurea receptor 1 , sulfonylurea receptor , sulphonylurea receptor 1
| GENE ID | SPECIES |
|---|---|
| 423072 | Gallus gallus |
| 451056 | Pan troglodytes |
| 654490 | Macaca mulatta |
| 6833 | Homo sapiens |
| 20927 | Mus musculus |
| 485402 | Canis lupus familiaris |
| 538996 | Bos taurus |
| 100158245 | Sus scrofa |
| 100722700 | Cavia porcellus |
| 25559 | Rattus norvegicus |
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