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ABCC8 Proteins

(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed\; however, the transcript variants have not been fully described. [provided by RefSeq, Jul 2008].

recommended

ABCC8 Protein (AA 611-710) (GST tag) (ABIN1305467)

ABCC8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

ABCC8 Protein (AA 1298-1581) (His tag) (ABIN3087972)

Crystallography grade ABCC8 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

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recommended

ABCC8 Protein (AA 195-311) (His tag) (ABIN3087970)

Crystallography grade ABCC8 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

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ABCC8 Proteins by Grade

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ABCC8 Proteins by Origin

Find ABCC8 Proteins for a variety of species such as anti-Human ABCC8. The species listed below are among those available. Click on a link to go to the corresponding products.

ABCC8 Proteins by Source

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ABCC8 Proteins by Protein Type

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ABCC8 Proteins by Application

Find ABCC8 Proteins validated for a specific application such as WB, ELISA, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular ABCC8 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

ABCC8 Protein (AA 611-710) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1305467

Quantity 10 μg

Datasheet Datasheet

ABCC8 Protein (AA 1298-1581) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3087972

Quantity 1 mg

Datasheet Datasheet

ABCC8 Protein (AA 195-311) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3087970

Quantity 1 mg

Datasheet Datasheet

ABCC8 Protein (AA 606-1004) (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3087971

Quantity 1 mg

Datasheet Datasheet

ABCC8 Protein (AA 1-1581) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3114467

Quantity 1 mg

Datasheet Datasheet

ABCC8 Protein (AA 679-929) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7407961

Quantity 100 μg

Datasheet Datasheet

ABCC8 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2714263

Quantity 20 μg

Datasheet Datasheet

ABCC8 Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2751627

Quantity 5 applications

Datasheet Datasheet

Aliases for ABCC8 Proteins

ATP binding cassette subfamily C member 8 (ABCC8) Proteins
ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8) Proteins
ATP binding cassette subfamily C member 8 (Abcc8) Proteins
ABC36 Proteins
D930031B21Rik Proteins
HHF1 Proteins
HI Proteins
HRINS Proteins
MRP8 Proteins
PHHI Proteins
SUR Proteins
Sur Proteins
SUR1 Proteins
Sur1 Proteins
SUR1delta2 Proteins
TNDM2 Proteins

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ABCC8 Proteins by Grade

ABCC8 Proteins by Origin

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ABCC8 Proteins by Protein Type

ABCC8 Proteins by Application

Popular ABCC8 Proteins

Aliases for ABCC8 Proteins

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