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anti-Human ELL3 Antibodies:
anti-Mouse (Murine) ELL3 Antibodies:
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Human Polyclonal ELL3 Primary Antibody for WB - ABIN529235
Suzuki, Miyawaki, Okuyama, Murata, Ando, Kato, Takagi, Takagi, Murate, Saito, Kojima: Ribavirin-induced intracellular GTP depletion activates transcription elongation in coagulation factor VII gene expression. in The Biochemical journal 2012
Authors demonstrated that ER(alpha), GATA3 and FOXA1 form a transcriptional complex with Ell3 to regulate IL-20 expression in ER(+) breast cancer cells. FOXA1 represses IL-20 expression, whereas GATA3 and ER(alpha) activate it.
Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival
Ell3 stabilizes p53 following cisplatin treatment via its effects on ubiquitin-dependent and -independent proteasomal degradation pathways in breast cancer cells.
Ell3 may play a critical role in promoting oncogenesis in breast cancer by regulating cell proliferation and cancer stem cell properties via the ERK1/2 signaling pathway
Study found that Ell3, a member of the Ell (eleven-nineteen lysine-rich leukemia gene) family of RNA Pol II elongation factors, occupies enhancers in embryonic stem cells.
The present results suggest that Ell3 promotes the differentiation of mouse embryonic stem cells by activating the expression of epithelial-mesenchymal transition-related genes and by suppressing p53 expression.
Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA (By similarity).
RNA polymerase II elongation factor ELL3
, elongation factor RNA polymerase II-like 3
, RNA polymerase II elongation factor ELL3-like