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The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.
E3 ubiquitin-protein ligase TRIM32
, tripartite motif-containing 32
, TAT-interactive protein, 72-KD
, tripartite motif containing 32
, 72 kDa Tat-interacting protein
, tripartite motif-containing protein 32
, zinc finger protein HT2A
, zinc-finger protein HT2A
, bM468K2.2 (tripartite motif protein 32)
, tripartite motif protein 32
, zinc finger protein 117