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anti-Human Adenosine A2a Receptor Antibodies:
anti-Mouse (Murine) Adenosine A2a Receptor Antibodies:
anti-Rat (Rattus) Adenosine A2a Receptor Antibodies:
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Dog (Canine) Monoclonal Adenosine A2a Receptor Primary Antibody for CyTOF, FACS - ABIN447986
Khoa, Montesinos, Reiss, Delano, Awadallah, Cronstein: Inflammatory cytokines regulate function and expression of adenosine A(2A) receptors in human monocytic THP-1 cells. in Journal of immunology (Baltimore, Md. : 1950) 2001
Show all 8 Pubmed References
Dog (Canine) Polyclonal Adenosine A2a Receptor Primary Antibody for ICC, IF - ABIN152752
Ren, Lin, Cao, Yang, Lu, Liu, Chen, Yang, Tian, Wang, Li, Wang, Chen, Ji, Zhang: CD73 is associated with poor prognosis in HNSCC. in Oncotarget 2016
Rhesus Monkey Polyclonal Adenosine A2a Receptor Primary Antibody for ELISA, WB - ABIN185549
Rétey, Adam, Honegger, Khatami, Luhmann, Jung, Berger, Landolt: A functional genetic variation of adenosine deaminase affects the duration and intensity of deep sleep in humans. in Proceedings of the National Academy of Sciences of the United States of America 2005
Show all 2 Pubmed References
Human Polyclonal Adenosine A2a Receptor Primary Antibody for IF (p), IHC (p) - ABIN686797
Cao, Dai, Wei, Han, Guan, Li, Liu, Xiao, Li: Effects of cordycepin on spontaneous alternation behavior and adenosine receptors expression in hippocampus. in Physiology & behavior 2017
Ex vivo lung perfusion with adenosine A2A receptor agonist allows prolonged cold preservation of lungs donated after cardiac death.
Adenosine A2A receptor contributes to ischemic brain damage in newborn piglet.
Pretreatment strategy with adenosine A2A receptor agonist attenuates reperfusion injury in a preclinical porcine lung transplantation model.
mRNA for adenosine A(1), A(2A), A(2B (show ADRA2B Antibodies)), and A(3) receptors was expressed in arterioles and venules. Protein for A(1), A(2A), and A(2B (show ADRA2B Antibodies)), but not A(3), was detected in both microvessel types and was further demonstrated on vascular endothelial cells
Study reveals presence of adenosine A(2A) and A(2B (show ADRA2B Antibodies)) receptors as well as a role for them in lacrimal gland secretion, and especially in synergy with purinergic and cholinergic stimulation.
genetic association studies in population in Germany: Data suggest that an SNP in ADORA2A (1976T/C, rs5751876) is associated with interoceptive (resting) and exteroceptive (executive function/task-based) processing in frontal lobe and insular cortex neural networks. Facilitated processing of interoceptive/exteroceptive information in salience network is suggested to promote development of anxiety and anxiety disorders.
A2A receptor stimulation promotes collagen type III synthesis via the activation of canonical and non-canonical beta-catenin (show CTNNB1 Antibodies), consistent with a role for A2A receptors in dermal fibrosis and scarring.
It is significantly associated with hippocampal volume and the minor allele of rs9608282 in ADORA2A is associated with larger hippocampal volumes and better memory.
Study corroborated results from a previous report that described interactions between ADORA2A and CYP1A2 (show CYP1A2 Antibodies) polymorphisms and coffee consumption in Parkinson's disease.
However, the contribution of the A2AR to the control of impulsive reward seeking remains unknown. Using mice that were exposed to differential reward of low rate (DRL) schedules during Pavlovian-conditioning, second-order schedule discrimination, and the 5-choice serial reaction time task (5 (show KCNK15 Antibodies)-CSRTT), we demonstrate that deficits of A2AR function promote impulsive responses.
Western blot analysis indicates that the A2A receptor is more abundant in the hippocampus of medial temporal lobe epilepsy patients compared to control individuals. Immunoreactivity against the A2A receptor predominates in astrocytes staining positively for the glial fibrillary acidic protein (show GFAP Antibodies).
Results suggest that the combination of the ADORA2A rs2298383TT and MTHFR (show MTHFR Antibodies) 1298AC-677CT genotypes might lead to a low risk of nodule formation in patients treated with methotrexate.
results unveil intracellular signaling pathways targeted by the A2AR, some of which might be key in modulating neutrophil functions.
Calcium modulates calmodulin-ACTN1 (show ACTN1 Antibodies) interaction with and agonist-dependent internalization of the adenosine A2A receptor.
A2A AR activation on BBB (show ALMS1 Antibodies) endothelial cells offers a therapeutic window that can be fine-tuned for drug delivery to the brain and has potential as a CNS drug-delivery technology.
Behavioral, anatomical and neurochemical studies to assess psychotic-like symptoms in adult male and female A2AR KO and wild-type littermates. Results bolster the adenosine hypothesis of schizophrenia by demonstrating behavioral and anatomical alterations associated with the specific deletion of adenosine A2AR. These findings resemble most of the relevant phenotype features of the human disorder.
Adenosine receptor A2A drives pathological angiogenesis in the oxygen-induced retinopathy mouse model by promoting glycolysis in endothelial cells via the ERK (show EPHB2 Antibodies)/Akt (show AKT1 Antibodies)/HIF-1alpha (show HIF1A Antibodies) pathway.
it is concluded that the anxiolytic-like activities of rubimetide and typical agonist peptides of the FPR2 (show FPR2 Antibodies) were mediated successively by the PGD2 (show PTGDS Antibodies)-DP1 (show REEP5 Antibodies) receptor, adenosine-A2A receptor, and GABA-GABAA (show GABRg1 Antibodies) receptor systems downstream of the FPR2 (show FPR2 Antibodies).
Study focused on the impact of A2A receptor deletion (A2A receptor knockout, A2AKO) on motivation for social exploration. Although A2AKO mice showed an anxious profile, they displayed higher levels of sociability and were less sensitive to social novelty. c-Fos immunoreactivity in A2AKO mice was higher in anterior cingulate and amygdala compared to wild type mice.
Data indicate A2ARs exert minor effects in un-stressed myocardium and selectively suppress NFkappaB and JAK (show JAK3 Antibodies)-STAT (show STAT1 Antibodies) signalling and cardiac injury without influencing cardiac depression in endotoxemia.
The three receptor sets considered (mAChR (show CHRM3 Antibodies), AR and TrkB (show NTRK2 Antibodies) receptors) intervene in modulating the conditions of the competition between nerve endings.
High A2aR expression is associated with Melanoma Metastasis.
These novel findings indicate that adenosine suppresses REM (show REM1 Antibodies) sleep via A2AR in the OB of rodents.
The findings suggest that disruption of the protective A2AR amplifies inflammation to accelerate glomerular damage and endogenous macrophage A2ARs are essential to protect from progressive kidney fibrosis.
Adenosine A2A receptor immunoreactivity is localized at the highest levels of the striatum and external globus pallidus.
Activation of adenosine A(2A) receptors inhibited ROS (show ROS1 Antibodies) production by LPS (show IRF6 Antibodies)-stimulated equine neutrophils in a cAMP-dependent manner.
This gene encodes a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. The encoded protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.
adenosine A2a receptor
, adenosine receptor A2a
, adenosine receptor A2a.1
, A2a adenosine receptor
, adenosine receptor A2a-like
, adenosine receptor subtype A2a
, A2a, Rs
, Adenosine A2a-receptor