Browse our RALB Proteins (Ralb)

Human V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb) interaction partners

1. our work provides new insight into the specific roles of Ras effector pathways in acute myeloid leukemia (show BCL11A Proteins) and has identified RALB signaling as a key survival pathway

2. This study identifies a novel regulatory crosstalk between Ral (show rala Proteins) and Arf6 (show ARF6 Proteins) that controls Ral (show rala Proteins) function in cells.

3. High RALB expression is associated with acute myeloid leukemia (show BCL11A Proteins).

4. Inhibition of Ral (show rala Proteins) GTPases Using a Stapled Peptide Approach.

5. These findings suggest that RalB might be one of the targets for facilitating the invasive phenotype of malignant gliomas induced by GGTase-I.

6. striking isoform-specific consequences of distinct CAAX-signaled posttranslational modifications that contribute to the divergent subcellular localization and activity of RalA (show rala Proteins) and RalB.

7. expression of K-Ras (show HRAS Proteins) and RalB and possibly RalA (show rala Proteins) proteins is critical for maintaining low levels of p53 (show TP53 Proteins), and down-regulation of these GTPases reactivates p53 (show TP53 Proteins) by significantly enhancing its stability, contributing to suppression of malignant transformation

8. High RALB mRNA expression is associated with non-small-cell lung cancer growth and progression.

9. Integrin alpha(v (show ITGAV Proteins))beta expression and the resulting KRAS-RalB-NF-kappaB (show NFKB1 Proteins) pathway were both necessary and sufficient for tumour initiation, anchorage independence, self-renewal and erlotinib resistance.

10. nutrient starvation induces RALB deubiquitylation by accumulation and relocalization of the deubiquitylase USP33 (show USP33 Proteins) to RALB-positive vesicles

Mouse (Murine) V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb) interaction partners

1. This study identifies a novel regulatory crosstalk between Ral (show rala Proteins) and Arf6 (show ARF6 Proteins) that controls Ral (show rala Proteins) function in cells.

2. striking isoform-specific consequences of distinct CAAX-signaled posttranslational modifications that contribute to the divergent subcellular localization and activity of RalA (show rala Proteins) and RalB.

3. findings show either RALA (show rala Proteins) or RALB is sufficient for tumor growth; either RALA (show rala Proteins) or RALB is sufficient for cell proliferation; RALA (show rala Proteins) and RALB act in a redundant fashion

4. Endogenous RalB plays a negative role in the ingestion process of Fc gamma receptor (show FCGR1A Proteins)-mediated macrophage phagocytosis.