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Full name:: anti-T-Cell Lymphoma Invasion and Metastasis 2 Antibodies (TIAM2)

On www.antibodies-online.com are 52 T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2) Antibodies from 12 different suppliers available. Additionally we are shipping TIAM2 Proteins (3) and many more products for this protein. A total of 65 TIAM2 products are currently listed.

Synonyms:: 3000002F19Rik, mKIAA2016, STEF, TIAM-2, TIAM2

list all antibodies	Gene Name	GeneID	UniProt
	TIAM2	26230	Q8IVF5
	TIAM2	24001	Q6ZPF3
Anti-Rat TIAM2	TIAM2	100362710
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Top referenced anti-TIAM2 Antibodies

Human Polyclonal TIAM2 Primary Antibody for ICC, IF - ABIN4359660 : Artym, Swatkoski, Matsumoto, Campbell, Petrie, Dimitriadis, Li, Mueller, Bugge, Gucek, Yamada: Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network. in The Journal of cell biology 2015 (PubMed)

More Antibodies against TIAM2 Interaction Partners

Human T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2) interaction partners

The authors show that the Rac1 selective guanine nucleotide exchange factor Sif and TIAM1-like Exchange Factor STEF, also known as TIAM2, localises to the nuclear envelope, co-localises with key perinuclear proteins and regulates the activity of perinuclear Rac1.
Tiam2/Rac are key components of EphB2 trans-endocytosis and are important for cell repulsion.
Results provide evidence that Sp1 positively controls TIAM2S transcription and that Sp1-mediated transcriptional activation is essential for TIAM2S ectopic expression in liver cancer cells.
Knockdown of TIAM2 could up-regulate the expression of E-cadherin.
TIAM2 expression was undetectable in normal human liver but was induced in all HCC cell lines and in 86% (78/91) of HCC biopsies.
stef gene expressed in a stage- and region-specific manner in the mouse brain
STEF protein is a guanine nucleotide exchange factor that specifically activates Rac1 in vitro and in cultured cells, which may lead to changes in the actin cytoskeletal network.

Mouse (Murine) T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2) interaction partners

specificity of PDZ domain and the molecular origin
The findings suggest a new role for STEF in Focal adhesion disassembly and cell migration through microtubules-mediated mechanisms.
Crystal structures of the PH-CC-Ex regions revealed a single globular domain, PHCCEx domain, comprising a conventional PH subdomain associated with an antiparallel coiled coil of CC subdomain and a novel three-helical globular Ex subdomain.
STEF is an activator of cortical neuronal migration.
Extracellular and intracellular information is integrated by STEF to modulate the balance of Rho GTPase activities in the growth cone and control growth cone behavior.
Phosphorylation of STEF by Rho-kinase exerts the inhibitory effect on the function of STEF.
Results describe the purification, crystallization and X-ray data collection of the Tiam1 and Tiam2 PH-CC-Ex regions.

TIAM2 Antigen Profile

Antigen Summary

This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with TIAM2

T-cell lymphoma invasion and metastasis 2 (TIAM2) antibody
T cell lymphoma invasion and metastasis 2 (Tiam2) antibody
T-cell lymphoma invasion and metastasis 2a (tiam2a) antibody
T-cell lymphoma invasion and metastasis 2 (Tiam2) antibody
T-lymphoma invasion and metastasis-inducing protein 2 (LOC100598161) antibody

3000002F19Rik antibody
mKIAA2016 antibody
STEF antibody
TIAM-2 antibody
TIAM2 antibody

Protein level used designations for TIAM2

SIF and TIAM1-like exchange factor , T-lymphoma invasion and metastasis-inducing protein 2 , RAS-related C3 botulinum substrate 1, guanine nucleotide exchange factor 1 , T-cell lymphoma invasion and metastasis 2 , T-cell lymphoma invasion and metastasis 2; RAS-related C3 botulinum substrate 1, guanine nucleotide exchange factor 1 , TIAM-2 , T-lymphoma invasion and metastasis-inducing protein 2-like

GENE ID	SPECIES
26230	Homo sapiens
24001	Mus musculus
421648	Gallus gallus
472168	Pan troglodytes
484045	Canis lupus familiaris
100155014	Sus scrofa
100223155	Taeniopygia guttata
100334442	Danio rerio
100362710	Rattus norvegicus
100391318	Callithrix jacchus
100544801	Meleagris gallopavo
100598161	Nomascus leucogenys

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Show all anti-T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2) Antibodies with Pubmed References

Human T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2) interaction partners

Mouse (Murine) T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2) interaction partners

Antigen Summary

Alternative names and synonyms associated with TIAM2

Protein level used designations for TIAM2