Browse our anti-CD40 Ligand (CD40LG) Antibodies

Full name:: anti-CD40 Ligand Antibodies (CD40LG)

On www.antibodies-online.com are 626 CD40 Ligand (CD40LG) Antibodies from 36 different suppliers available. Additionally we are shipping CD40 Ligand Proteins (122) and CD40 Ligand Kits (111) and many more products for this protein. A total of 883 CD40 Ligand products are currently listed.

Synonyms:: CD40-L, Cd40l, CD154, gp39, hCD40L, HIGM1, IGM, IMD3, Ly-62, Ly62, T-BAM, Tnfsf5, TRAP

list all antibodies	Gene Name	GeneID	UniProt
	CD40LG	959	P29965
	CD40LG	21947	P27548
	CD40LG	84349	Q9Z2V2
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Most Popular Reactivities for anti-CD40 Ligand (CD40LG) Antibodies

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anti-Human CD40 Ligand Antibodies:

anti-Mouse (Murine) CD40 Ligand Antibodies:

anti-Rat (Rattus) CD40 Ligand Antibodies:

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Top referenced anti-CD40 Ligand Antibodies

Mouse (Murine) Monoclonal CD40 Ligand Primary Antibody for BR, FACS - ABIN1176849 : Carbone, Ruggiero, Terrazzano, Palomba, Manzo, Fontana, Spits, Kärre, Zappacosta: A new mechanism of NK cell cytotoxicity activation: the CD40-CD40 ligand interaction. in The Journal of experimental medicine 1997 (PubMed)
Show all 23 Pubmed References
Mouse (Murine) Monoclonal CD40 Ligand Primary Antibody for BR, IHC (fro) - ABIN2688993 : DeKruyff, Gieni, Umetsu: Antigen-driven but not lipopolysaccharide-driven IL-12 production in macrophages requires triggering of CD40. in Journal of immunology (Baltimore, Md. : 1950) 1997 (PubMed)
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Mouse (Murine) Monoclonal CD40 Ligand Primary Antibody for FACS - ABIN2688995 : Dunn, Luedecker, Haugen, Clegg, Farr: Thymic overexpression of CD40 ligand disrupts normal thymic epithelial organization. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1997 (PubMed)
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Mouse (Murine) Monoclonal CD40 Ligand Primary Antibody for Func, ICC - ABIN1302520 : Fischbein, Ardehali, Yun, Schoenberger, Laks, Irie, Dempsey, Cheng, Fishbein, Bonavida: CD40 signaling replaces CD4+ lymphocytes and its blocking prevents chronic rejection of heart transplants. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
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Mouse (Murine) Monoclonal CD40 Ligand Primary Antibody for Func, ICC - ABIN1302930 : Wu, Zhou, Zheng, Liu: CD28-independent induction of T helper cells and immunoglobulin class switches requires costimulation by the heat-stable antigen. in The Journal of experimental medicine 1998 (PubMed)
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Human Monoclonal CD40 Ligand Primary Antibody for Func, ICC - ABIN2752002 : Brams, Black, Padlan, Hariharan, Leonard, Chambers-Slater, Noelle, Newman: A humanized anti-human CD154 monoclonal antibody blocks CD154-CD40 mediated human B cell activation. in International immunopharmacology 2001 (PubMed)
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Human Monoclonal CD40 Ligand Primary Antibody for Func, ICC - ABIN2749175 : Barnhart, Ford, Bhushan, Song, Covey: A polymorphic CD40 ligand (CD154) molecule mediates CD40-dependent signalling but interferes with the ability of soluble CD40 to functionally block CD154:CD40 interactions. in Immunology 2000 (PubMed)
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Mouse (Murine) Monoclonal CD40 Ligand Primary Antibody for Func, ICC - ABIN1302448 : Howard, Miga, Vanderlugt, Dal Canto, Laman, Noelle, Miller: Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis. in The Journal of clinical investigation 1999 (PubMed)
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Human Monoclonal CD40 Ligand Primary Antibody for Func, ICC - ABIN2749183 : Berner, Wolf, Hummel, Müller, Reuss-Borst: Increased expression of CD40 ligand (CD154) on CD4+ T cells as a marker of disease activity in rheumatoid arthritis. in Annals of the rheumatic diseases 2000 (PubMed)
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Baboon Monoclonal CD40 Ligand Primary Antibody for FACS - ABIN2688992 : Fuleihan, Ramesh, Horner, Ahern, Belshaw, Alberg, Stamenkovic, Harmon, Geha: Cyclosporin A inhibits CD40 ligand expression in T lymphocytes. in The Journal of clinical investigation 1994 (PubMed)
Show all 4 Pubmed References

More Antibodies against CD40 Ligand Interaction Partners

Chimpanzee CD40 Ligand (CD40LG) interaction partners

specific cross-linking with trimeric recombinant HIV-1 gp140 revealed reduced sensitivity for inhibition of CD154 up-regulation in chimpanzees, requiring fourfold higher concentrations of viral protein

Atlantic Salmon (Salmo salar) CD40 Ligand (CD40LG) interaction partners

identification and functional characterization of CD40L and CD40 (show CD40 Antibodies) from Atlantic salmon (Salmo salar); results provide evidence for the existence of a functional CD40L mediated costimulatory pathway in Atlantic salmon

Human CD40 Ligand (CD40LG) interaction partners

the CD40 (show CD40 Antibodies) rs1883832 T allele acts as a risk factor for increased susceptibility to sepsis and may be involved in the process of sepsis through regulation of CD40 (show CD40 Antibodies) expression and plasma sCD40L levels.
Overexpression of CD40L-WT/CD40L-M in CD40 (show CD40 Antibodies)+ NSCLC cells increased SA-beta-gal (show GLB1 Antibodies) staining activity and inhibited DNA synthesis and cell proliferation.
T cell-stimulated CLL cells actively recruited monocytes, and CD40L was identified as the responsible T-cell factor that mediated recruitment.
this study shows that decreased serum levels of soluble CD40L correlate in treated patients with Relapsing-Remitting Multiple Sclerosis
In this first X chromosome-wide association study of adult patients with IBD, we identified an IBD susceptibility locus with genome-wide significance at rs2427870 on chrXq26.3, located 66 kbp upstream of CD40LG and 83.4 kbp upstream of ARHGEF6 [OR, 1.22; combined p = 3.79 x 10-15].
Study indicates that the rs1126535C/T polymorphism of CD154 gene was involved in the progression of Chinese SLE patients, probably by affecting the expression of CD154.
study found that plasma CD40L was associated with acute chest syndrome (ACS), and that sickle cell anemia (SCA)patients with a lifetime history of ACS (ACS+) presented significantly higher plasma CD40L and TSP-1 than patients who had never experienced ACS (ACS-)
this paper demonstrates importance of CD40 (show CD40 Antibodies)/CD40L signaling on IL-10 (show IL10 Antibodies)-producing regulatory B cells in Chinese children with Henoch-Schonlein purpura nephritis
Soluble CD40 ligand derived from serum is not correlated with early stage of multiple sclerosis.
Analysis of the early events after receptor engagement revealed that both TNF (show TNF Antibodies) and CD40L activate the classical NF-kappaB (show NFKB1 Antibodies) pathway, and confirm activation of the alternative by the latter. Furthermore, using genetic and pharmacological inhibition of the classical pathway we show that activation of the alternative occurs independently of the former. This reveals insights into NF-kappaB (show NFKB1 Antibodies) signaling by CD40L and TNF (show TNF Antibodies) in endoth...

Mouse (Murine) CD40 Ligand (CD40LG) interaction partners

MR1 (show MR1 Antibodies)-induced bone accrual was associated with increased Treg development and elevated production of cytotoxic T lymphocyte antigen 4 (show CTLA4 Antibodies), a costimulation inhibitor that promotes T cell anergy and CD8 (show CD8A Antibodies)+ T cell expression of the bone anabolic ligand Wnt (show WNT2 Antibodies)-10b.
These results suggest that CD40-activated CD40L reverse signalling has striking and opposite effects on the growth and elaboration of dendrites among major classes of brain neurons by PKC-dependent mechanisms.
Soluble CD40 ligand directly alters glomerular permeability and may act as a circulating permeability factor in focal segmental glomerulosclerosis.
studies identify a novel molecular mechanism of regulation of CD40L by the transcription factor GLI2 (show GLI2 Antibodies) in the tumor microenvironment downstream of CCR3 (show CCR3 Antibodies) signaling
our results unambiguously demonstrate that while CD40L is critical to generate effective primary CD8 (show CD8A Antibodies)(+) T-cell responses also under inflammatory conditions, CD40L expression by CD8 (show CD8A Antibodies)(+) T cells themselves is dispensable in acute lymphocytic choriomeningitis virus infection.
Platelets promote allergic asthma through the expression of CD154.
CD40L does not play a functional role in experimental acute pancreatitis
The tissue-specific, activation-dependent and reversible expression of CD40L fully mimics the physiological induction and disappearance of the molecule from the surface of murine T lymphocytes.
there is a major involvement of the CD40 (show CD40 Antibodies)-CD40L signaling pathway in long-term brain dysfunction in an animal model of sepsis.
Report targeting and liposomal drug delivery of methotrexate to CD40L expressing T cells for treatment of autoimmune diseases.

Pig (Porcine) CD40 Ligand (CD40LG) interaction partners

CD40 ligand has a role in inducing endothelial dysfunction in human and porcine coronary artery endothelial cells

Cow (Bovine) CD40 Ligand (CD40LG) interaction partners

Results demonstrated greater CD40 (show CD40 Antibodies) and CD40L expression on fresh mononuclear leukocytes obtained from animals in the clinical stage of Johne's Disease.

Rhesus Monkey CD40 Ligand (CD40LG) interaction partners

Both two-trimer and four-trimer forms of macaque CD40L were active in B-cell proliferation assays using macaque and human cells.

CD40 Ligand (CD40LG) Antigen Profile

Antigen Summary

The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.

Alternative names and synonyms associated with CD40 Ligand (CD40LG)

CD40 ligand (CD40LG) antibody
CD40 ligand (cd40l) antibody
TNF superfamily member 5 (cd40l) antibody
CD40 ligand (Cd40lg) antibody

CD40-L antibody
Cd40l antibody
CD154 antibody
gp39 antibody
hCD40L antibody
HIGM1 antibody
IGM antibody
IMD3 antibody
Ly-62 antibody
Ly62 antibody
T-BAM antibody
Tnfsf5 antibody
TRAP antibody

Protein level used designations for anti-CD40 Ligand (CD40LG) Antibodies

CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) , CD40 ligand , TNF superfamily member 5 , CD40 antigen ligand , CD40-L , T-B cell-activating molecule , T-cell antigen Gp39 , TNF-related activation protein , tumor necrosis factor (ligand) superfamily member 5 , tumor necrosis factor ligand superfamily member 5 , CD40 ligand CD154 , tumor necrosis factor (ligand) superfamily, member 5 , human : hyper-IgM syndrome , uncharacterized protein LOC100358388 , putative CD154 (CD40 ligand) , CD154 protein

GENE ID	SPECIES
473802	Pan troglodytes
100286596	Salmo salar
100136698	Oncorhynchus mykiss
959	Homo sapiens
21947	Mus musculus
84349	Rattus norvegicus
397231	Sus scrofa
403468	Canis lupus familiaris
282387	Bos taurus
100358388	Oryctolagus cuniculus
100733664	Cavia porcellus
493850	Felis catus
395485	Gallus gallus
767628	Ovis aries
574160	Macaca mulatta

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Show all anti-CD40 Ligand (CD40LG) Antibodies with Pubmed References