Browse our anti-EGFR (EGFR) Antibodies

Full name:: anti-Epidermal Growth Factor Receptor Antibodies (EGFR)

On www.antibodies-online.com are 2481 Epidermal Growth Factor Receptor (EGFR) Antibodies from 47 different suppliers available. Additionally we are shipping EGFR Kits (148) and EGFR Proteins (138) and many more products for this protein. A total of 2839 EGFR products are currently listed.

Synonyms:: 9030024J15Rik, AI552599, C-erb, c-erbB, CG10079, D-Egf, d-egf-r, D-EGFR, dEgfr, dEGFR1, der, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DER1, DER flb, Dmel\\CG10079, DmHD-33, EFG-R, Egf, Egf-r, egfr, egfr1, EGFR12, EGFR15, EK2-6, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, Erbb, ErbB-1, ERBB1, Erbb2, Errb1, Errp, flb, HD-33, HER1, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57Ea, l(2)57EFa, mENA, mor1, PIG61, top, top/DER, top/flb, Torpedo/DER, torpedo/egfr, wa-2, wa2, Wa5

list all antibodies	Gene Name	GeneID	UniProt
	EGFR	1956	P00533
	EGFR	24329
	EGFR	13649	Q01279
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Most Popular Reactivities for anti-EGFR (EGFR) Antibodies

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anti-Human EGFR Antibodies:

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Relevant Pathways for anti-EGFR Antibodies

EGFR Downregulation

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Top referenced anti-EGFR Antibodies

Human Polyclonal EGFR Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899925 : Sarup, Jin, Turin, Bai, Beryt, Brdlik, Higaki, Jorgensen, Lau, Lindley, Liu, Ni, Rozzelle, Kumari, Watson, Zhang, Shepard: Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts. in Molecular cancer therapeutics 2008 (PubMed)
Show all 7 Pubmed References
Human Polyclonal EGFR Primary Antibody for WB - ABIN1881287 : Zanardi, Yei, Lichtenstein, Tollefson, Wold: Distinct domains in the adenovirus E3 RIDalpha protein are required for degradation of Fas and the epidermal growth factor receptor. in Journal of virology 2003 (PubMed)
Show all 7 Pubmed References
Human Polyclonal EGFR Primary Antibody for WB - ABIN3042517 : Ge, Yu, Petitte, Zhang: Epidermal growth factor-induced proliferation of chicken primordial germ cells: involvement of calcium/protein kinase C and NFKB1. in Biology of reproduction 2009 (PubMed)
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Human Polyclonal EGFR Primary Antibody for IC, IHC (p) - ABIN285476 : Larsen, Stockhausen, Poulsen: Cell adhesion and EGFR activation regulate EphA2 expression in cancer. in Cellular signalling 2010 (PubMed)
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Human Polyclonal EGFR Primary Antibody for DB, WB - ABIN1881285 : Aifa, Aydin, Nordvall, Lundström, Svensson, Hermanson: A basic peptide within the juxtamembrane region is required for EGF receptor dimerization. in Experimental cell research 2004 (PubMed)
Show all 5 Pubmed References
Human Polyclonal EGFR Primary Antibody for DB, WB - ABIN1881284 : Adams, McKern, Ward: Signalling by the type 1 insulin-like growth factor receptor: interplay with the epidermal growth factor receptor. in Growth factors (Chur, Switzerland) 2004 (PubMed)
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Human Polyclonal EGFR Primary Antibody for DB, WB - ABIN1881286 : Ichinose, Murata, Yanagida, Sako: EGF signalling amplification induced by dynamic clustering of EGFR. in Biochemical and biophysical research communications 2004 (PubMed)
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Human Polyclonal EGFR Primary Antibody for WB - ABIN2801937 : Ilekis, Stark, Scoccia: Possible role of variant RNA transcripts in the regulation of epidermal growth factor receptor expression in human placenta. in Molecular reproduction and development 1995 (PubMed)
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Human Polyclonal EGFR Primary Antibody for DB, WB - ABIN1881283 : Kuribayashi, Kataoka, Kurabayashi, Miura: Evidence that basal activity, but not transactivation, of the epidermal growth factor receptor tyrosine kinase is required for insulin-like growth factor I-induced activation of extracellular signal-regulated kinase in oral carcinoma cells. in Endocrinology 2004 (PubMed)
Show all 5 Pubmed References
Human Polyclonal EGFR Primary Antibody for DB, WB - ABIN1944845 : Kapoor, Zhan, Johnson, ORourke: Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cells. in Molecular and cellular biology 2003 (PubMed)
Show all 5 Pubmed References

More Antibodies against EGFR Interaction Partners

Horse (Equine) Epidermal Growth Factor Receptor (EGFR) interaction partners

Results indicated that most periocular squamous cell carcinomas of horses expressed epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2 (show ERBB2 Antibodies)).

Fruit Fly (Drosophila melanogaster) Epidermal Growth Factor Receptor (EGFR) interaction partners

stress-dependent EGFR/MAPK promotes gut regeneration via a novel mechanism that operates independently of Insulin/Pi3K/TOR signaling.
EGFR/ARF6 regulation of Hh signaling stimulates oncogenic Ras tumor overgrowth in Drosophila.
Graf (show ARHGAP26 Antibodies) functions to downregulate EGFR signaling.
Data show that EGFR controls the proper formation of brain neuroblasts by regulating the number, survival and proneural gene expression of neuroectodermal progenitor cells which suggest that EGFR signalling is crucially important for patterning and early neurogenesis of the brain.
The activity of Gro (show CXCL1 Antibodies) is antagonized by EGFR signaling, which inhibits Gro (show CXCL1 Antibodies)-dependent repression via p-ERK (show MAPK1 Antibodies) mediated phosphorylation.
These results reveal that ESCRT-0 (ESCRT-0 components stam (show STAM Antibodies) and hrs)mutants inhibit EGFR signaling by disrupting Rhomboid endosomal trafficking in the ligand-producing cells.
we find that EGFR regulates the apical determinant Crb and the extracellular matrix regulator Serp, two factors previously known to control tube length. EGFR regulates the organisation of endosomes in which Crb and Serp proteins are loaded
Here we uncover a cell non-autonomous requirement for the Epidermal growth factor receptor (Egfr) pathway in the lateral epidermis for sustained dpp (show TGFb Antibodies) expression in the LE. Specifically, we demonstrate that Egfr pathway activity in the lateral epidermis prevents expression of the gene scarface (scaf), encoding a secreted antagonist of JNK (show MAPK8 Antibodies) signaling
Loss of Usp5 (show USP5 Antibodies) results in upregulation of Notch (show NOTCH1 Antibodies) signaling and downregulation of RTK signaling by EGF receptor (EGFR) and Sevenless (Sev), leading to impaired photoreceptor development.
These data demonstrate a strong genetic link between dG9a and the EGFR signaling pathway.

Zebrafish Epidermal Growth Factor Receptor (EGFR) interaction partners

Combination of an EGFR tyrosine kinase inhibitor and a NF-kappaB (show NFKB1 Antibodies) inhibitor effectively suppressed cetuximab-resistant HNSCC and interfering with the EGFR-LTbeta (show LTB Antibodies) interaction reverses resistance.
Study demonstrated that IGF-I (show IGF1 Antibodies) can stimulate egfr expression in both follicles cell culture and intact follicles promoting oocyte maturation.
These results indicate that maintenance of Pgrmc1 (show PGRMC1 Antibodies) signaling is required for Egfr expression on zebrafish oocyte cell membranes and for conserving the functions of Egfr in maintaining meiotic arrest through estrogen activation of Gper (show GPER Antibodies).
EGFR signaling in vertebrate oocytes can prevent meiotic progression.
the expression of EGFR was mainly restricted to the follicle cells with little expression in the oocytes

Human Epidermal Growth Factor Receptor (EGFR) interaction partners

Concurrent mutations, in genes such as CDKN2B (show CDKN2B Antibodies) or RB1 (show RB1 Antibodies), were associated with worse clinical outcome in lung adenocarcinoma patients with EGFR active mutations.
ER-alpha36/EGFR signaling loop promotes growth of hepatocellular carcinoma cells
High EGFR expression is associated with colorectal cancer.
High EGFR expression is associated with gefitinib resistance in lung cancer.
High EGFR expression is associated with tumor-node-metastasis in nonsmall cell lung cancer.
Data suggest that Thr264 in TRPV3 (show TRPV3 Antibodies) is key ERK1 (show MAPK3 Antibodies) phosphorylation site mediating EGFR-induced sensitization of TRPV3 (show TRPV3 Antibodies) to stimulate signaling pathways involved in regulating skin homeostasis. (TRPV3 (show TRPV3 Antibodies) = transient receptor potential cation channel subfamily V member-3 (show TRPV3 Antibodies); ERK1 (show MAPK3 Antibodies) = extracellular signal-regulated kinase-1 (show MAPK3 Antibodies); EGFR = epidermal growth factor receptor)
The EGFR mutation frequency in Middle East and African patients is higher than that shown in white populations but still lower than the frequency reported in Asian populations.
EGFR-containing exosomes derived from cancer cells could favour the development of a liver-like microenvironment promoting liver-specific metastasis.
The results reveal that the EGF (show EGF Antibodies)-STAT3 (show STAT3 Antibodies) signaling pathway promotes and maintains colorectal cancer (CRC (show CALR Antibodies))stemness. In addition, a crosstalk between STAT3 (show STAT3 Antibodies) and Wnt (show WNT2 Antibodies) activates the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway, which is also responsible for cancer stemness. Thus, STAT3 (show STAT3 Antibodies) is a putative therapeutic target for CRC (show CALR Antibodies) treatment.
This result indicated that T790M mutation is not only associated with EGFR-TKI resistance but also may play a functional role in the malignant progression of lung adenocarcinoma.

Mouse (Murine) Epidermal Growth Factor Receptor (EGFR) interaction partners

The results indicate that EGFR and its activation are critical for YAP (show YAP1 Antibodies)-mediated suppression of TGF-beta1 (show TGFB1 Antibodies)-induced apoptosis. This study provides a new understanding of the regulatory mechanism underlying the determination of cell fate in response to TGF-beta1 (show TGFB1 Antibodies)-mediated simultaneous apoptosis and epithelial mesenchymal transformation.
our findings suggested the concept of the EGFR activated Osteoarthritis (OA) subpopulation and illustrated the mechanism of EGFR signaling in regulating cartilage homeostasis. Gefitinib could be a promising disease-modifying drug for this OA subpopulation treatment.
Cortactin (show CTTN Antibodies) expression in carcinoma cells and its known involvement in the EGFR pathway suggest a role for this protein as a target for laryngeal squamous cell carcinoma therapy.
results suggest ADAM17/EGFR-driven PLCgamma1 and PKC pathways as important promoters of TG1 expression during terminal keratinocyte differentiation.
Suggest caution for the proposed therapeutic strategy of combined signal transducer and activator of transcription (show STAT1 Antibodies)/epidermal growth factor receptor inhibition for cancer treatment with respect to cardiotoxity.
Stress-specific p38 MAPK (show MAPK14 Antibodies) activation is sufficient to drive EGFR endocytosis but not its nuclear translocation.
miR (show MLXIP Antibodies)-145 can decrease MUC5AC expression by inhibiting EGFR and alleviating airway remodeling. This indicates that miR (show MLXIP Antibodies)-145 may be used as a molecular predictor for airway remodeling.
To evaluate the role of EGFR signaling in the articular cartilage, we studied a cartilage-specific Egfr-deficient (CKO) mouse model (Col2-Cre EgfrWa5/flox). These mice developed early cartilage degeneration at 6 mo of age. By 2 mo of age, although their gross cartilage morphology appears normal, CKO mice had a drastically reduced number of superficial chondrocytes and decreased lubricant secretion at the surface.
All these findings suggest that EGCG can resist skin senility effectively. And the EGFR with relate of downstream proteins are implicated in the skin aging.
Using a murine model for glioblastoma driven by a single genetic driver, the study suggests differences in EGFR activation contribute to tumor heterogeneity and aggressiveness.

Pig (Porcine) Epidermal Growth Factor Receptor (EGFR) interaction partners

this study shows that anemonin may ameliorate LPS (show IRF6 Antibodies)-induced intestinal injury and improve restoration by regulating the TGF-b1 and EGFR signaling pathways
Syndecan-4 (show SDC4 Antibodies) mediates porcine respiratory and reproductive syndrome virus entry by interacting with EGFR.
These results indicate that cAMP and oocyte-secreted factors cooperate to promote EGF receptor functionality in developing cumulus oocyte complexes, representing a key component of the acquisition of oocyte developmental competence.
patients experiencing gefitinib dose reduction or short-term treatment interruption due to toxicities did not show inferior survival, compared to those receiving full dose of gefitinib in non-small cell lung cancer patients with EGFR mutation
Report EGFR expression in the normal pancreas.
Injury and activation of purinergic receptors and direct activation of EGFR via EGF (show EGF Antibodies) induce distinct downstream pathways.
Data suggest that the mechanism of hypoxia-induced increased activation of EGFR kinase is mediated by nNOS (show NOS1 Antibodies)-derived nitric oxide.
EGFR, VEGFR (show KDR Antibodies) and FGFR (show FGFR2 Antibodies) are expressed in porcine oviduct and endometrium during the time of implantation [review]
the restricted presence of the functional full-size receptor to the epithelial layer indicates a specific role during early embryonic development, whereas truncated EGF-R forms may potentially regulate contractions and blood flow in the oviduct
The phase-related expression of EGF (show EGF Antibodies) and EGFR in the endothelium of the uterine artery and its branches suggest the modulatory effect of EGF (show EGF Antibodies) and its receptor on the uterine artery and the region supplying these vessels.

Cow (Bovine) Epidermal Growth Factor Receptor (EGFR) interaction partners

Stimulation of bovine oviduct epithelial cell EGFR with EGF (show EGF Antibodies) (human recombinant EGF (show EGF Antibodies)) alone or with EGF (show EGF Antibodies) in postovulatory/follicular phases (not luteal phase) up-regulates phosphorylation of MAPKs; heat blocks effects of EGF (show EGF Antibodies) on phosphorylation of MAPKs.
Expression of the erbB/HER receptor family in the bovine uterus during the sexual cycle and the relation of this family to serum sex steroids.
Regulation of the sperm EGFR by ouabain leads to initiation of the acrosome reaction.
EGFR may simultaneously activate c-Src (show SRC Antibodies) and PI3K to amplify the oxytocin signaling to increase the output of PGF (show PGF Antibodies)(2 alpha) in endometrial epithelial cells.
results indicate that arginase induction depends in part on epidermal growth factor (EGF (show EGF Antibodies)) receptor activity, and that EGFR inhibitors may attenuate vascular remodeling without affecting nitric oxide release
Data suggest that epidermal growth factor (EGF (show EGF Antibodies)) and EGF (show EGF Antibodies) receptors are important paracrine and/or autocrine regulators of spermatogenesis in bovine.
MT1-MMP (show MMP14 Antibodies) has a role in signaling events mediating EGFR transactivation
possible cooperative role of the EGF (show EGF Antibodies) and HGF (show HGF Antibodies) pathways and indicate that cross-talk between their respective receptors may modulate mammary gland development in the cow
EGFR is stimulated during capacitation via PKA activation. More activation induces the acrosome reaction, which is induced by GPCR via EGFR transactivation by a signaling pathway involving PKA, SRC & metalloproteinase & effectors PI3K, PLC & PKC.

Rabbit Epidermal Growth Factor Receptor (EGFR) interaction partners

These results show that MMP-2 (show MMP2 Antibodies) activates the EGFR and triggers downstream signaling pathways increasing Reactive Oxygen Species formation and promoting vasoconstriction.

EGFR Antigen Profile

Antigen Summary

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Alternative names and synonyms associated with EGFR

epidermal growth factor receptor (EGFR) antibody
Epidermal growth factor receptor (Egfr) antibody
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) (egfra) antibody
epidermal growth factor receptor (egfr1) antibody
epidermal growth factor receptor (LOC5564544) antibody
epidermal growth factor receptor (Egfr) antibody

9030024J15Rik antibody
AI552599 antibody
C-erb antibody
c-erbB antibody
CG10079 antibody
D-Egf antibody
d-egf-r antibody
D-EGFR antibody
dEgfr antibody
dEGFR1 antibody
der antibody
DER/EGFR antibody
DER/faint little ball antibody
DER/top antibody
DER/torpedo antibody
DER1 antibody
DER flb antibody
Dmel\\CG10079 antibody
DmHD-33 antibody
EFG-R antibody
Egf antibody
Egf-r antibody
egfr antibody
egfr1 antibody
EGFR12 antibody
EGFR15 antibody
EK2-6 antibody
El antibody
Elp antibody
Elp-1 antibody
Elp-B1 antibody
Elp-B1RB1 antibody
Erbb antibody
ErbB-1 antibody
ERBB1 antibody
Erbb2 antibody
Errb1 antibody
Errp antibody
flb antibody
HD-33 antibody
HER1 antibody
l(2)05351 antibody
l(2)09261 antibody
l(2)57DEFa antibody
l(2)57Ea antibody
l(2)57EFa antibody
mENA antibody
mor1 antibody
PIG61 antibody
top antibody
top/DER antibody
top/flb antibody
Torpedo/DER antibody
torpedo/egfr antibody
wa-2 antibody
wa2 antibody
Wa5 antibody

Protein level used designations for EGFR

, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , CG10079-PA CG10079-PB DER-Ellipse EGF-receptor EGFR Egf receptor Egfr-PA Egfr-PB drosophila epidermal growth factor receptor homologue ellipse ellipse torpedo epidermal growth factor receptor faint little ball morphological defects 1 torpedo torpedo/DER erbb1a avian erythroblastic leukemia viral (v-erb-b) oncogene homolog cell growth inhibiting protein 40 cell proliferation-inducing protein 61 proto-oncogene c-ErbB-1 receptor tyrosine-protein kinase erbB-1 EGFR-related peptide Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1) avian erythroblastic leukemia viral (v-erbB) oncogene homolog epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1) waved 2 CER epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) egf receptor receptor tyrosine kinase ErbB1

GENE ID	SPECIES
100067755	Equus caballus
37455	Drosophila melanogaster
378478	Danio rerio
778955	Ciona intestinalis
5564544	Aedes aegypti
1956	Homo sapiens
24329	Rattus norvegicus
13649	Mus musculus
396494	Gallus gallus
397070	Sus scrofa
404306	Canis lupus familiaris
407217	Bos taurus
100008806	Oryctolagus cuniculus
100725363	Cavia porcellus
780479	Ovis aries
613027	Macaca mulatta

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Show all anti-Epidermal Growth Factor Receptor (EGFR) Antibodies with Pubmed References