Browse our anti-EGFR (EGFR) Antibodies

Full name:: anti-Epidermal Growth Factor Receptor Antibodies (EGFR)

On www.antibodies-online.com are 2749 Epidermal Growth Factor Receptor (EGFR) Antibodies from 46 different suppliers available. Additionally we are shipping EGFR Kits (141) and EGFR Proteins (138) and many more products for this protein. A total of 3101 EGFR products are currently listed.

Synonyms:: 9030024J15Rik, AI552599, C-erb, c-erbB, CG10079, D-Egf, d-egf-r, D-EGFR, dEgfr, dEGFR1, der, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DER1, DER flb, Dmel\\CG10079, DmHD-33, EFG-R, Egf, Egf-r, egfr, egfr1, EGFR12, EGFR15, EK2-6, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, Erbb, ErbB-1, ERBB1, Erbb2, Errb1, Errp, flb, HD-33, HER1, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57Ea, l(2)57EFa, mENA, mor1, PIG61, top, top/DER, top/flb, Torpedo/DER, torpedo/egfr, wa-2, wa2, Wa5

list all antibodies	Gene Name	GeneID	UniProt
	EGFR	1956	P00533
Anti-Rat EGFR	EGFR	24329
	EGFR	13649	Q01279
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Most Popular Reactivities for anti-EGFR (EGFR) Antibodies

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anti-Human EGFR Antibodies:

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Relevant Pathways for anti-EGFR Antibodies

EGFR Downregulation

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Top referenced anti-EGFR Antibodies

Human Polyclonal EGFR Primary Antibody for IC, IHC (p) - ABIN285476 : Larsen, Stockhausen, Poulsen: Cell adhesion and EGFR activation regulate EphA2 expression in cancer. in Cellular signalling 2010 (PubMed)
Show all 6 Pubmed References
Human Polyclonal EGFR Primary Antibody for WB - ABIN1881287 : Zanardi, Yei, Lichtenstein, Tollefson, Wold: Distinct domains in the adenovirus E3 RIDalpha protein are required for degradation of Fas and the epidermal growth factor receptor. in Journal of virology 2003 (PubMed)
Show all 6 Pubmed References
Human Polyclonal EGFR Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899925 : Sarup, Jin, Turin, Bai, Beryt, Brdlik, Higaki, Jorgensen, Lau, Lindley, Liu, Ni, Rozzelle, Kumari, Watson, Zhang, Shepard: Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts. in Molecular cancer therapeutics 2008 (PubMed)
Show all 6 Pubmed References
Human Polyclonal EGFR Primary Antibody for IHC - ABIN966041 : Buerger, Nagel-Wolfrum, Kunz, Wittig, Butz, Hoppe-Seyler, Groner: Sequence-specific peptide aptamers, interacting with the intracellular domain of the epidermal growth factor receptor, interfere with Stat3 activation and inhibit the growth of tumor cells. in The Journal of biological chemistry 2003 (PubMed)
Show all 5 Pubmed References
Human Polyclonal EGFR Primary Antibody for CyTOF, FACS - ABIN4900628 : Weissenbacher, Vrekoussis, Roeder, Makrigiannakis, Mayr, Ditsch, Friese, Jeschke, Dian: Analysis of Epithelial Growth Factor-Receptor (EGFR) Phosphorylation in Uterine Smooth Muscle Tumors: Correlation to Mucin-1 and Galectin-3 Expression. in International journal of molecular sciences 2013 (PubMed)
Show all 5 Pubmed References
Human Polyclonal EGFR Primary Antibody for DB, WB - ABIN1881285 : Aifa, Aydin, Nordvall, Lundström, Svensson, Hermanson: A basic peptide within the juxtamembrane region is required for EGF receptor dimerization. in Experimental cell research 2004 (PubMed)
Show all 5 Pubmed References
Human Polyclonal EGFR Primary Antibody for DB, WB - ABIN1881284 : Adams, McKern, Ward: Signalling by the type 1 insulin-like growth factor receptor: interplay with the epidermal growth factor receptor. in Growth factors (Chur, Switzerland) 2004 (PubMed)
Show all 5 Pubmed References
Human Polyclonal EGFR Primary Antibody for DB, WB - ABIN1881286 : Ichinose, Murata, Yanagida, Sako: EGF signalling amplification induced by dynamic clustering of EGFR. in Biochemical and biophysical research communications 2004 (PubMed)
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Human Polyclonal EGFR Primary Antibody for WB - ABIN2801937 : Ilekis, Stark, Scoccia: Possible role of variant RNA transcripts in the regulation of epidermal growth factor receptor expression in human placenta. in Molecular reproduction and development 1995 (PubMed)
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Human Polyclonal EGFR Primary Antibody for DB, WB - ABIN1881283 : Kuribayashi, Kataoka, Kurabayashi, Miura: Evidence that basal activity, but not transactivation, of the epidermal growth factor receptor tyrosine kinase is required for insulin-like growth factor I-induced activation of extracellular signal-regulated kinase in oral carcinoma cells. in Endocrinology 2004 (PubMed)
Show all 5 Pubmed References

More Antibodies against EGFR Interaction Partners

Horse (Equine) Epidermal Growth Factor Receptor (EGFR) interaction partners

Results indicated that most periocular squamous cell carcinomas of horses expressed epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2 (show ERBB2 Antibodies)).

Fruit Fly (Drosophila melanogaster) Epidermal Growth Factor Receptor (EGFR) interaction partners

Graf (show ARHGAP26 Antibodies) functions to downregulate EGFR signaling.
Data show that EGFR controls the proper formation of brain neuroblasts by regulating the number, survival and proneural gene expression of neuroectodermal progenitor cells which suggest that EGFR signalling is crucially important for patterning and early neurogenesis of the brain.
The activity of Gro (show CXCL1 Antibodies) is antagonized by EGFR signaling, which inhibits Gro (show CXCL1 Antibodies)-dependent repression via p-ERK (show MAPK1 Antibodies) mediated phosphorylation.
These results reveal that ESCRT-0 (ESCRT-0 components stam (show STAM Antibodies) and hrs)mutants inhibit EGFR signaling by disrupting Rhomboid endosomal trafficking in the ligand-producing cells.
we find that EGFR regulates the apical determinant Crb and the extracellular matrix regulator Serp, two factors previously known to control tube length. EGFR regulates the organisation of endosomes in which Crb and Serp proteins are loaded
Here we uncover a cell non-autonomous requirement for the Epidermal growth factor receptor (Egfr) pathway in the lateral epidermis for sustained dpp (show TGFb Antibodies) expression in the LE. Specifically, we demonstrate that Egfr pathway activity in the lateral epidermis prevents expression of the gene scarface (scaf), encoding a secreted antagonist of JNK (show MAPK8 Antibodies) signaling
Loss of Usp5 (show USP5 Antibodies) results in upregulation of Notch (show NOTCH1 Antibodies) signaling and downregulation of RTK signaling by EGF receptor (EGFR) and Sevenless (Sev), leading to impaired photoreceptor development.
These data demonstrate a strong genetic link between dG9a and the EGFR signaling pathway.
Avermectin directly interacts with EGFR and leads to the activation of the EGFR/AKT (show AKT1 Antibodies)/ERK (show MAPK1 Antibodies) pathway.
The dorsoventral patterning and EGFR signaling genes play essential roles in correct identity determination and differentiation of lateral glia in the Drosophila nervous system.

Zebrafish Epidermal Growth Factor Receptor (EGFR) interaction partners

Combination of an EGFR tyrosine kinase inhibitor and a NF-kappaB (show NFKB1 Antibodies) inhibitor effectively suppressed cetuximab-resistant HNSCC and interfering with the EGFR-LTbeta (show LTB Antibodies) interaction reverses resistance.
Study demonstrated that IGF-I (show IGF1 Antibodies) can stimulate egfr expression in both follicles cell culture and intact follicles promoting oocyte maturation.
These results indicate that maintenance of Pgrmc1 (show PGRMC1 Antibodies) signaling is required for Egfr expression on zebrafish oocyte cell membranes and for conserving the functions of Egfr in maintaining meiotic arrest through estrogen activation of Gper (show GPER Antibodies).
EGFR signaling in vertebrate oocytes can prevent meiotic progression.
the expression of EGFR was mainly restricted to the follicle cells with little expression in the oocytes

Human Epidermal Growth Factor Receptor (EGFR) interaction partners

Structural analysis demonstrated that the coupling of synthetic, natural or newly designed compounds impacts the conformational space of EGFR and HER2 (show ERBB2 Antibodies) differently.
This review also discusses the current prognostic status of EGFR in glioblastomas and other gliomas, and highlights gaps in previous studies. This serves as an update for the medical community about the role of EGFR gene alterations in gliomas and specifically glioblastomas, as a means for targeted treatment and prognosis.
EGFR is confirmed a poor prognostic factor in resected gastric cancers. We firstly describe a mutually exclusive overexpression of EGFR and AKT1 (show AKT1 Antibodies) with potential prognostic implications, suggesting the relevance of this pathway for the growth of gastric cancers.
The detection of EGFR mutation in peripheral blood can be applied as an effective index for EGFR-TKI (Gefitinib) treatment in patients with esophageal carcinoma.
Correlation exists between EGFR mutations and histologic subtypes of invasive adenocarcinoma or air bronchograms on CT images, which could use to predict EGFR mutation status in patients with pulmonary adenocarcinoma.
High EGFR expression is associated with drug resistance in non-small cell lung cancer.
EGFR mutations are associated with lung cancers. In the H1975 cells, 72% of the reads harbored both L858R and T790M mutations, and 22% of the reads harbored neither mutation.
Although blood had a better specificity for detecting EGFR mutations, the absence of blood positivity should not necessarily be construed as confirmed negativity. Patients with negative results for blood should decidedly undergo further biopsies to ascertain EGFR mutations
Study demonstrated the radiological and clinical features could be used to prognosticate epidermal growth factor receptor mutation subtypes in exon 19 and 21.
Lung adenocarcinoma patients positive for the EGFR Exon 21 L858R mutation had a higher positive rate of intraoperative pleural lavage cytology than those not possessing EGFR mutations.

Mouse (Murine) Epidermal Growth Factor Receptor (EGFR) interaction partners

Cortactin (show CTTN Antibodies) expression in carcinoma cells and its known involvement in the EGFR pathway suggest a role for this protein as a target for laryngeal squamous cell carcinoma therapy.
results suggest ADAM17/EGFR-driven PLCgamma1 and PKC pathways as important promoters of TG1 expression during terminal keratinocyte differentiation.
Suggest caution for the proposed therapeutic strategy of combined signal transducer and activator of transcription (show STAT1 Antibodies)/epidermal growth factor receptor inhibition for cancer treatment with respect to cardiotoxity.
Stress-specific p38 MAPK (show MAPK14 Antibodies) activation is sufficient to drive EGFR endocytosis but not its nuclear translocation.
miR (show MLXIP Antibodies)-145 can decrease MUC5AC expression by inhibiting EGFR and alleviating airway remodeling. This indicates that miR (show MLXIP Antibodies)-145 may be used as a molecular predictor for airway remodeling.
To evaluate the role of EGFR signaling in the articular cartilage, we studied a cartilage-specific Egfr-deficient (CKO) mouse model (Col2-Cre EgfrWa5/flox). These mice developed early cartilage degeneration at 6 mo of age. By 2 mo of age, although their gross cartilage morphology appears normal, CKO mice had a drastically reduced number of superficial chondrocytes and decreased lubricant secretion at the surface.
All these findings suggest that EGCG can resist skin senility effectively. And the EGFR with relate of downstream proteins are implicated in the skin aging.
Using a murine model for glioblastoma driven by a single genetic driver, the study suggests differences in EGFR activation contribute to tumor heterogeneity and aggressiveness.
These results suggest that EphA2/Efna1/Egfr genes, linked to a possible control by miR-200a and miR-26b, could be proposed as novel CRC prognostic biomarkers. Moreover, EphA2 could be linked to a mechanism of resistance to cetuximab alternative to KRAS mutations.
These results collectively suggest that sustained activation of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling in endothelial cells might be a cause of heart failure through suppressing neuregulin-ErbB signaling.

Pig (Porcine) Epidermal Growth Factor Receptor (EGFR) interaction partners

this study shows that anemonin may ameliorate LPS (show IRF6 Antibodies)-induced intestinal injury and improve restoration by regulating the TGF-b1 and EGFR signaling pathways
Syndecan-4 (show SDC4 Antibodies) mediates porcine respiratory and reproductive syndrome virus entry by interacting with EGFR.
These results indicate that cAMP and oocyte-secreted factors cooperate to promote EGF receptor functionality in developing cumulus oocyte complexes, representing a key component of the acquisition of oocyte developmental competence.
patients experiencing gefitinib dose reduction or short-term treatment interruption due to toxicities did not show inferior survival, compared to those receiving full dose of gefitinib in non-small cell lung cancer patients with EGFR mutation
Report EGFR expression in the normal pancreas.
Injury and activation of purinergic receptors and direct activation of EGFR via EGF (show EGF Antibodies) induce distinct downstream pathways.
Data suggest that the mechanism of hypoxia-induced increased activation of EGFR kinase is mediated by nNOS (show NOS1 Antibodies)-derived nitric oxide.
EGFR, VEGFR (show KDR Antibodies) and FGFR (show FGFR2 Antibodies) are expressed in porcine oviduct and endometrium during the time of implantation [review]
the restricted presence of the functional full-size receptor to the epithelial layer indicates a specific role during early embryonic development, whereas truncated EGF-R forms may potentially regulate contractions and blood flow in the oviduct
The phase-related expression of EGF (show EGF Antibodies) and EGFR in the endothelium of the uterine artery and its branches suggest the modulatory effect of EGF (show EGF Antibodies) and its receptor on the uterine artery and the region supplying these vessels.

Cow (Bovine) Epidermal Growth Factor Receptor (EGFR) interaction partners

Stimulation of bovine oviduct epithelial cell EGFR with EGF (show EGF Antibodies) (human recombinant EGF (show EGF Antibodies)) alone or with EGF (show EGF Antibodies) in postovulatory/follicular phases (not luteal phase) up-regulates phosphorylation of MAPKs; heat blocks effects of EGF (show EGF Antibodies) on phosphorylation of MAPKs.
Expression of the erbB/HER receptor family in the bovine uterus during the sexual cycle and the relation of this family to serum sex steroids.
Regulation of the sperm EGFR by ouabain leads to initiation of the acrosome reaction.
EGFR may simultaneously activate c-Src (show SRC Antibodies) and PI3K to amplify the oxytocin signaling to increase the output of PGF (show PGF Antibodies)(2 alpha) in endometrial epithelial cells.
results indicate that arginase induction depends in part on epidermal growth factor (EGF (show EGF Antibodies)) receptor activity, and that EGFR inhibitors may attenuate vascular remodeling without affecting nitric oxide release
Data suggest that epidermal growth factor (EGF (show EGF Antibodies)) and EGF (show EGF Antibodies) receptors are important paracrine and/or autocrine regulators of spermatogenesis in bovine.
MT1-MMP (show MMP14 Antibodies) has a role in signaling events mediating EGFR transactivation
possible cooperative role of the EGF (show EGF Antibodies) and HGF (show HGF Antibodies) pathways and indicate that cross-talk between their respective receptors may modulate mammary gland development in the cow
EGFR is stimulated during capacitation via PKA activation. More activation induces the acrosome reaction, which is induced by GPCR via EGFR transactivation by a signaling pathway involving PKA, SRC & metalloproteinase & effectors PI3K, PLC & PKC.

EGFR Antigen Profile

Antigen Summary

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Alternative names and synonyms associated with EGFR

epidermal growth factor receptor (EGFR) antibody
Epidermal growth factor receptor (Egfr) antibody
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) (egfra) antibody
epidermal growth factor receptor (egfr1) antibody
epidermal growth factor receptor (LOC5564544) antibody
epidermal growth factor receptor (Egfr) antibody

9030024J15Rik antibody
AI552599 antibody
C-erb antibody
c-erbB antibody
CG10079 antibody
D-Egf antibody
d-egf-r antibody
D-EGFR antibody
dEgfr antibody
dEGFR1 antibody
der antibody
DER/EGFR antibody
DER/faint little ball antibody
DER/top antibody
DER/torpedo antibody
DER1 antibody
DER flb antibody
Dmel\\CG10079 antibody
DmHD-33 antibody
EFG-R antibody
Egf antibody
Egf-r antibody
egfr antibody
egfr1 antibody
EGFR12 antibody
EGFR15 antibody
EK2-6 antibody
El antibody
Elp antibody
Elp-1 antibody
Elp-B1 antibody
Elp-B1RB1 antibody
Erbb antibody
ErbB-1 antibody
ERBB1 antibody
Erbb2 antibody
Errb1 antibody
Errp antibody
flb antibody
HD-33 antibody
HER1 antibody
l(2)05351 antibody
l(2)09261 antibody
l(2)57DEFa antibody
l(2)57Ea antibody
l(2)57EFa antibody
mENA antibody
mor1 antibody
PIG61 antibody
top antibody
top/DER antibody
top/flb antibody
Torpedo/DER antibody
torpedo/egfr antibody
wa-2 antibody
wa2 antibody
Wa5 antibody

Protein level used designations for EGFR

, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , CG10079-PA CG10079-PB DER-Ellipse EGF-receptor EGFR Egf receptor Egfr-PA Egfr-PB drosophila epidermal growth factor receptor homologue ellipse ellipse torpedo epidermal growth factor receptor faint little ball morphological defects 1 torpedo torpedo/DER erbb1a avian erythroblastic leukemia viral (v-erb-b) oncogene homolog cell growth inhibiting protein 40 cell proliferation-inducing protein 61 proto-oncogene c-ErbB-1 receptor tyrosine-protein kinase erbB-1 EGFR-related peptide Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1) avian erythroblastic leukemia viral (v-erbB) oncogene homolog epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1) waved 2 CER epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) egf receptor receptor tyrosine kinase ErbB1

GENE ID	SPECIES
100067755	Equus caballus
37455	Drosophila melanogaster
378478	Danio rerio
778955	Ciona intestinalis
5564544	Aedes aegypti
1956	Homo sapiens
24329	Rattus norvegicus
13649	Mus musculus
396494	Gallus gallus
397070	Sus scrofa
404306	Canis lupus familiaris
407217	Bos taurus
100008806	Oryctolagus cuniculus
100725363	Cavia porcellus
780479	Ovis aries
613027	Macaca mulatta

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Show all anti-Epidermal Growth Factor Receptor (EGFR) Antibodies with Pubmed References