Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human PKC zeta Antibodies:
anti-Mouse (Murine) PKC zeta Antibodies:
anti-Rat (Rattus) PKC zeta Antibodies:
Go to our pre-filtered search.
Human Polyclonal PKC zeta Primary Antibody for ICC, IF - ABIN4345863
Verbist, Guy, Milasta, Liedmann, Kamiński, Wang, Green: Metabolic maintenance of cell asymmetry following division in activated T lymphocytes. in Nature 2016
Human Polyclonal PKC zeta Primary Antibody for IHC (p) - ABIN2476259
Hirai, Chida: Protein kinase Czeta (PKCzeta): activation mechanisms and cellular functions. in Journal of biochemistry 2003
Human Polyclonal PKC zeta Primary Antibody for IHC (p), WB - ABIN391018
Lerner-Marmarosh, Miralem, Gibbs, Maines: Regulation of TNF-alpha-activated PKC-zeta signaling by the human biliverdin reductase: identification of activating and inhibitory domains of the reductase. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007
Protein kinase c (show PKC Antibodies) activity restricts dendritic arborization during embryonic brain circuit development through synaptotropic stabilization of dynamic processes.
Intestinal I/R induced the membrane translocation and phosphorylation of PKCzeta. Pretreatment with the PKCzeta activator phosphatidylcholine (show SGMS2 Antibodies) remarkably attenuated gut (show GUSB Antibodies) injury by suppressing apoptosis. H/R induced PKCzeta to combine with TRAF2 (show TRAF2 Antibodies), which was phosphorylated by PKCzeta at Ser (show SIGLEC1 Antibodies)(55), but not at Ser (show SIGLEC1 Antibodies)(11), under intestinal I/R or H/R conditions
these results conclude that miR (show MLXIP Antibodies)-25 targets PKCzeta and protects osteoblastic cells from Dex via activating AMPK (show PRKAA1 Antibodies) signaling.
PKCzeta was specifically involved in ACOT7 (show ACOT7 Antibodies) depletion-mediated cell cycle arrest as an upstream molecule of the p53 (show TP53 Antibodies)-p21 (show CDKN1A Antibodies) signaling pathway in MCF7 human breast carcinoma and A549 human lung carcinoma cells.
we found that Wnt3a (show WNT3A Antibodies) treatment rapidly induces hyperphosphorylation and stabilization of Dvl2 (show DVL2 Antibodies) and Dvl3 (show DVL3 Antibodies). Our findings suggest a model of positive regulation of PKCzeta-mediated Dvl (show DVL2 Antibodies) signaling activity, to produce a strong and sustained response to Wnt3a (show WNT3A Antibodies) treatment by stabilizing Dvl (show DVL2 Antibodies) protein levels.
The data demonstrate that PKCzeta expression regulates the maturation of neonatal T-cells into specific functional phenotypes and that environmental influences may work via PKCzeta to regulate these phenotypes and disease susceptibility.
This study demonstrated that zinc upregulates PKCzeta by activating GPR39 (show GPR39 Antibodies) to enhance the abundance of ZO-1 (show TJP1 Antibodies), thereby improving epithelial integrity in S. typhimurium-infected Caco-2 cells.
Inhibition of protein kinase C zeta expression in prostate cancer cells promoted chemotaxis of peripheral macrophages and acquisition of M2 phenotypic features. These results were further supported by the finding that silencing of endogenous protein kinase C zeta promoted the expression of prostate cancer cell-derived interleukin-4 (show IL4 Antibodies) and interleukin-10 (show IL10 Antibodies)
Here we provide the first evidence that PKC-zeta is a potential target for the treatment of COPD (show ARCN1 Antibodies) by selective small molecules
Study provides evidence for a novel PKC-zeta to p47phox interaction that is required for cell transformation from blebbishields and ROS (show ROS1 Antibodies) production in cancer cells.
FRET-based translocation assays reveal that insulin (show INS Antibodies) promotes the association of both p62 (show GTF2H1 Antibodies) and aPKC with the insulin (show INS Antibodies)-regulated scaffold IRS-1 (show IRS1 Antibodies).
the inhibition of PKCzeta or ceramide synthesis did not further improve glucose tolerance in Angptl4 (show ANGPTL4 Antibodies)(-/-) mice, suggesting that these molecules were major downstream effectors of Angptl4 (show ANGPTL4 Antibodies).
Immunoblotting, qPCR, ChIP and siRNA-mediated gene knockdown studies revealed that the activation of phosphatidylinositol 3-kinase/protein kinase C zeta pathways in poly(I:C)-stimulated cells underlies Sp1 (show SP1 Antibodies) phosphorylation and recruitment to the mCRAMP promoter, leading to enhanced transcription
APPL1 (show APPL1 Antibodies) enhances glucose uptake by modulating the activation and localization of PKCzeta, as well as its functional interaction with both PP2A (show PPP2R2B Antibodies) and myosin IIa.
Findings indicate PDZRN3 (show PDZRN3 Antibodies) regulates vascular permeability through a PKCzeta-containing complex.
Data (including data from studies in transgenic and knockout mice) suggest that Pkcz (protein kinase C zeta) activation is key for early compensatory pancreatic beta-cell proliferation in insulin (show INS Antibodies) resistance (overweight and diabetes type 2) by regulating downstream signal transduction components mTOR (mammalian target of rapamycin (show FRAP1 Antibodies) protein) and Ccnd2 (cyclin-D2 (show CCND2 Antibodies)).
androstenedione administration increased Akt1 (show AKT1 Antibodies) and PKC zeta phosphorylation in the muscle tissue of C57BL6 mice.
studies support a model wherein an alternative mechanism regulates PKCzeta-mediated insulin (show INS Antibodies) signalling that does not utilize conventional activation via agonist-evoked phosphorylation at the activation loop
PKCzeta/p62 (show GTF2H1 Antibodies) activation stimulated inflammatory cytokine production and enhanced IGF-I (show IGF1 Antibodies)-stimulated VSMC proliferation
Neuronal NF1 (show NF1 Antibodies)/RAS regulation of cyclic AMP (show TMPRSS5 Antibodies) requires atypical PKC zeta activation, which is perturbed in neurofibromatosis type 1 (show NF1 Antibodies).
These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.
chronic exposure to hypoxia leads to the emergence of cells lacking anti-replication activity of PKCzeta in the pulmonary artery adventitia.
inhibition of NO production by Ang-1 (show ANGPT1 Antibodies), via phosphorylation of eNOS (show NOS3 Antibodies) on Thr (show TRH Antibodies)(497) by PKC zeta, is responsible, at least in part, for inhibition of VEGF (show VEGFA Antibodies)-stimulated endothelial permeability by Ang-1 (show ANGPT1 Antibodies).
ceramide as a potent physiological modulator of the Na(+)-ATPase (show DNAH8 Antibodies), participating in a regulatory network in kidney cells and counteracting the stimulatory effect of PKA via PKCzeta.
Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta.
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.
protein kinase C, zeta
, protein kinase c type Z
, protein kinase C zeta type
, protein kinase C zeta type-like
, atypical protein kinase C
, protein kinase C zeta subspecies
, 14 - 3 - 3 - zeta isoform
, atypical protein kinase C zeta