PKC zeta Products
(Protein Kinase C, zeta (PRKCZ))
Categories
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured PKC zeta Categories
PKC zeta Antibodies
High quality antibodies with extensive validation data.
PKC zeta ELISA Kits
Reliable ELISA kits for a wide range of species.
PKC zeta Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PKC zeta Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
Cat. No.
ABIN6264247
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
Cat. No.
ABIN6256558
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
Cat. No.
ABIN562397
Quantity
100 μg
Datasheet
Datasheet
Recommended PKC zeta ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969724
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969723
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958930
Quantity
96 tests
Datasheet
Datasheet
Recommended PKC zeta Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
Cat. No.
ABIN5570094
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124655
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316282
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PKC zeta products
: "PKCζ in prostate cancer cells represses the recruitment and M2 polarization of macrophages in the prostate cancer microenvironment." in: Tumour biology, Vol. 39, Issue 6, pp. 1010428317701442, (2017) (PubMed).: "Metabolic maintenance of cell asymmetry following division in activated T lymphocytes." in: Nature, Vol. 532, Issue 7599, pp. 389-93, (2016) (PubMed).
: "Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota." in: Cancer research, Vol. 68, Issue 18, pp. 7403-8, (2008) (PubMed).
: "Regulation of TNF-alpha-activated PKC-zeta signaling by the human biliverdin reductase: identification of activating and inhibitory domains of the reductase." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 3949-62, (2007) (PubMed).
: "Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms." in: The Journal of biological chemistry, Vol. 281, Issue 44, pp. 33773-88, (2006) (PubMed).
: "Protein kinase Czeta (PKCzeta): activation mechanisms and cellular functions." in: Journal of biochemistry, Vol. 133, Issue 1, pp. 1-7, (2003) (PubMed).
: "Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes." in: European journal of biochemistry / FEBS, Vol. 216, Issue 2, pp. 597-606, (1993) (PubMed).
: "The cDNA sequence encoding human protein kinase C-zeta." in: Gene, Vol. 132, Issue 2, pp. 305-6, (1993) (PubMed).
Synonyms and alternative names related to PKC zeta
protein kinase C zeta L homeolog (prkcz.L), protein kinase C zeta (PRKCZ), protein kinase C zeta (prkcz), protein kinase C, zeta (PRKCZ), protein kinase C, zeta (Prkcz), protein kinase C zeta (Prkcz), protein kinase C, zeta (prkcz), 14-3-3-zetaisoform, AI098070, aPKCzeta, C80388, pkc-zeta, PKC-ZETA, pkc2, PKC2, Pkcz, pkcz, PKCzeta, PRKCZ, prkcz-A, r14-3-3, R74924, si:ch211-150o23.4, TPKC, zetaPKCProtein level used designations for PKC zeta
- protein kinase C, zeta
- protein kinase c type Z
- protein kinase C zeta type
- protein kinase C zeta type-like
- nPKC-zeta
- atypical protein kinase C
- protein kinase C zeta subspecies
- 14 - 3 - 3 - zeta isoform
- atypical protein kinase C zeta
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