For best experience we recommend to activate Javascript in your browser.

Browse our MIB2 Proteins (MIB2)

Full name:: Mindbomb Homolog 2 (Drosophila) Proteins (MIB2)

On www.antibodies-online.com are 9 Mindbomb Homolog 2 (Drosophila) (MIB2) Proteins from 4 different suppliers available. Additionally we are shipping MIB2 Antibodies (30) and MIB2 Kits (7) and many more products for this protein. A total of 46 MIB2 products are currently listed.

Synonyms:: 2210008I11Rik, mib2, skd, Zzank1, ZZZ5

list all proteins	Gene Name	GeneID	UniProt
	MIB2	142678	Q96AX9
	MIB2	76580	Q8R516
	MIB2	474147
Show all synonyms

MIB2 Proteins (MIB2) by Origin

Select your origin of interest

Relevant Pathways for MIB2 Proteins

Notch Signaling

More Proteins for MIB2 Interaction Partners

Human Mindbomb Homolog 2 (Drosophila) (MIB2) interaction partners

Missense p.V742G variant in MIB2 is associated with left ventricle hypertrabeculation/non-compaction and Menetrier-like gastropathy.
Here, we report a novel interaction between CYLD and MIB2 that supports the hypothesis that the CYLD/MIB2 interaction might play a pathogenic role in human cancer.
The DLAIS motif in MAVS was found to be critical for MIB2 binding, the ligation of K63-linked ubiquitin to TANK-binding kinase 1, and phosphorylation-mediated IRF3/7 activation.
identify MIB2 as a novel component of the activated BCL10 signaling complex and a missing link in the BCL10-dependent NF-kappaB signaling pathway.
Mib2 has functional similarities to Mib1, but might have distinct roles in Notch signaling as an E3 ubiquitin ligase
Skeletrophin, a novel RING molecule controlled by the chromatin remodeling complex, is down-regulated in melanoma.
skeletrophin is a novel ubiquitin ligase that targets the intracellular region of Jagged-2 and is aberrantly overexpressed in multiple myeloma cells.
skeletrophin might be a novel suppressor factor for melanoma invasion
Data identify Mind bomb-2 as an E3 ubiquitin ligase that interacts with and ubiquitinates the NR2B subunit of the NMDAR in mammalian cells.

Mouse (Murine) Mindbomb Homolog 2 (Drosophila) (MIB2) interaction partners

identify MIB2 as a novel component of the activated BCL10 signaling complex and a missing link in the BCL10-dependent NF-kappaB signaling pathway.
Mib2 has functional similarities to Mib1, but might have distinct roles in Notch signaling as an E3 ubiquitin ligase
created a targeted mutation of Mib2 and show that its phenotype is a variable penetrance, failure to close the cranial neural tube

Zebrafish Mindbomb Homolog 2 (Drosophila) (MIB2) interaction partners

Mib and Mib2 interact with Fih-1 that is involved in the hypoxia signaling pathway.
Zebrafish Mib and Mib2 are colocalized in transfected cells and function redundantly in regulating Notch signaling in embryos.

MIB2 Protein Profile

Protein Summary

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors (By similarity).

Alternative names and synonyms associated with MIB2

mindbomb E3 ubiquitin protein ligase 2 (MIB2)
mindbomb E3 ubiquitin protein ligase 2 (Mib2)
mindbomb E3 ubiquitin protein ligase 2 (mib2)
mindbomb E3 ubiquitin protein ligase 2 S homeolog (mib2.S)

2210008I11Rik protein
mib2 protein
skd protein
Zzank1 protein
ZZZ5 protein

Protein level used designations for MIB2

E3 ubiquitin-protein ligase MIB2 , mind bomb homolog 2 , mindbomb homolog 2 , novel zinc finger protein , novelzin , putative NF-kappa-B-activating protein 002N , skeletrophin , zinc finger ZZ type with ankyrin repeat domain protein 1 , zinc finger, ZZ type with ankyrin repeat domain 1 , dyslike , dystrophin-like protein , mind bomb-2 , RBSC-skeletrophin , RBSC-skeletrophin/dystrophin-like polypeptide , miblike , mindbomb E3 ubiquitin protein ligase 2 S homeolog

GENE ID	SPECIES
142678	Homo sapiens
76580	Mus musculus
474147	Rattus norvegicus
419408	Gallus gallus
560887	Danio rerio
100158426	Xenopus laevis

Selected quality suppliers for MIB2 Proteins (MIB2)

Did you look for something else?

Phone:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@antibodies-online.com