Browse our anti-Estrogen-Related Receptor alpha (ESRRA) Antibodies

Zebrafish Estrogen-Related Receptor alpha (ESRRA) interaction partners

1. ERRalpha is abundantly expressed in H(+)-pump-rich cells, a group of ionocytes responsible for H(+) secretion in the skin of developing embryos, and its expression is stimulated by acidic environments. Knockdown of ERRalpha impairs both basal and low pH-induced H(+) secretion in the yolk-sac (show ADCY10 Antibodies) skin, which is accompanied by decreased expression of H(+)-secreting-related transporters.

2. Results propose Estrogen Receptor (show ESR1 Antibodies)-Relatedalpha as a new regulator of morphogenetic movement during gastrulation, independently of cell fate determination.

Cow (Bovine) Estrogen-Related Receptor alpha (ESRRA) interaction partners

1. The results identify TGFB1 (show TGFB1 Antibodies) and ESRRA as likely transcriptional regulators of rumen epithelial development and energy metabolism, respectively, and provide targets for modulation of rumen development and function in the growing calf.

2. ERalpha (show ESR1 Antibodies), is only expressed in the caruncle of the placenta.

Medaka Estrogen-Related Receptor alpha (ESRRA) interaction partners

1. ERalpha (show ESR1 Antibodies) mRNA-expressing neurons (ERalpha (show ESR1 Antibodies) neurons) were distributed in some structures of the telencephalon, diencephalon, mesencephalon, and hindbrain.

Rabbit Estrogen-Related Receptor alpha (ESRRA) interaction partners

1. Findings suggest that PGF (show PGF Antibodies)(2alpha) regulates luteolysis by ESR1 (show ESR1 Antibodies) mRNA down-regulation.

Mouse (Murine) Estrogen-Related Receptor alpha (ESRRA) interaction partners

1. This work reveals a molecular mechanism by which ERRalpha-induced metabolic reprogramming promotes survival of lapatinib-resistant cancer cells.

2. the involvement of ERRalpha in the progression of cisplatin-induced AKI is probably through impaired mitochondrial dynamics

3. Localizing ESRRA binding sites in cortical chromatin, it has been shown that this nuclear receptor binds both differentially expressed energy-related and neurodevelopmental transcription factor genes during social challenge.

4. The Genomic Context and Corecruitment of SP1 Affect ERRalpha Coactivation by PGC-1alpha in Muscle Cells

5. findings highlight a MYC (show MYC Antibodies)/ERRalpha pathway that contributes to physiological and pathological bone loss by integrating the MYC (show MYC Antibodies)/ERRalpha axis to drive metabolic reprogramming during osteoclast differentiation

6. Study performed a structural and functional assessment of glutamatergic synapses on medium spiny neurons in the nucleus accumbens of Esrra-null mice, and discovered sex-specific alterations in miniature excitatory postsynaptic currents frequency and amplitude, reduced paired-pulse ratio, and reduction in glutamatergic synaptic vesicles consistent with altered functional connectivity

7. The nuclear receptor, estrogen-related receptor alpha (ERRalpha), was shown to regulate the expression of genes required for lactate utilization.

8. In bone, the effects of cholesterol, statin, and bisphosphonate on osteoclastogenesis require ERRalpha; and consequently, cholesterol-induced bone loss or bisphosphonate osteoprotection is lost in ERRalpha knockout mice.

9. We conclude that E2-induced ERRalpha expression in endothelium plays an important role for the E2-induced vasculoprotective effect

10. Exercise-induced changes in tumour LDH-B (show LDHB Antibodies) and MCT1 (show MCTS1 Antibodies) expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice

Human Estrogen-Related Receptor alpha (ESRRA) interaction partners

1. This work reveals a molecular mechanism by which ERRalpha-induced metabolic reprogramming promotes survival of lapatinib-resistant cancer cells.

2. data showed that activation of NF-kappaB (show NFKB1 Antibodies)/IL-6 (show IL6 Antibodies) is involved in ERRalpha induced migration and invasion of non-small cell lung cancer cells; it suggested that ERRalpha might be a potential target for non-small cell lung cancer treatment

3. Results show that ERRA is an interacting partner of PGC1a in a subset of human melanoma cells. Also, ERRA promotes mitochondrial oxidative metabolism in melanoma cells.

4. LSD1 (show KDM1A Antibodies) and ERRalpha coregulate several target genes involved in cell migration, including the MMP1 (show MMP1 Antibodies) matrix metallo-protease, also activated through H3K9 demethylation at the transcriptional start site.

5. TGF-beta (show TGFB1 Antibodies) treatment can trigger the epithelial-mesenchymal transition of osteosarcoma cells via ERRalpha/Snail (show SNAI1 Antibodies) pathways.

6. LC3B (show MAP1LC3B Antibodies) and ESRRA might be a useful prognostic factor in patients with muscle-invasive bladder cancer. The co-expression of LC3B (show MAP1LC3B Antibodies) and ESRRA might be a prognostic and therapeutic target for patients with bladder cancer.

7. These findings indicate that ERRalpha may serve as a novel molecular target for the treatment of endometrial cancer

8. Gls (show GLS Antibodies) is a novel ERRalpha target gene.

9. can trigger the proliferation and migration of colorectal cancer cells via up regulation of IL-8 (show IL8 Antibodies)

10. curcumin suppressed the ERRalpha gene expression through upregulation of miR (show MLXIP Antibodies)-125a. Data from this study revealed a novel mechanism for curcumin-mediated apoptotic cell death, which involves tumor cell killing via activating miR (show MLXIP Antibodies)-125a/ERRalpha pathway.

Pig (Porcine) Estrogen-Related Receptor alpha (ESRRA) interaction partners

1. Results show that miR (show MYLIP Antibodies)-125a inhibits porcine preadipocytes differentiation through targeting ERRa.

2. XCT790 significantly inhibited the expression of ERR alpha and lipid accumulation in porcine mature adipocytes.