Browse our C-MYC Proteins (MYC)

Full name:: V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) Proteins (MYC)

On www.antibodies-online.com are 34 V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Proteins from 8 different suppliers available. Additionally we are shipping C-MYC Antibodies (889) and C-MYC Kits (60) and many more products for this protein. A total of 1005 C-MYC products are currently listed.

Synonyms:: anon-WO03040301.171, AU016757, bHLHe39, bHLHe57, c-MYC, c-myc II, CG10798, CMyc, d-myc, da, dm, dm/dMyc, dm/myc, Dmel\CG10798, dmyc, dmyc1, EG:BACN5I9.1, l(1)G0139, l(1)G0354, l(1)G0359, LOC100136746, mMyc, MRTL, myc, myc-B, myc2, MYCC, Niard, Nird, RNCMYC, zc-myc

list all proteins	Gene Name	GeneID	UniProt
	MYC	4609	P01106
	MYC	24577	P09416
	MYC	17869	P01108
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C-MYC Proteins (MYC) by Origin

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Top referenced C-MYC Proteins

Human C-MYC Protein expressed in HEK-293 Cells - ABIN2715370 : Garcia-Sanz, Quintanilla, Lafita, Moreno-Bueno, García-Gutierrez, Tabor, Varela, Shiio, Larsson, Portillo, Leon: Sin3b interacts with Myc and decreases Myc levels. in The Journal of biological chemistry 2014 (PubMed)
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More Proteins for C-MYC Interaction Partners

Human V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

Menin functions as an oncogenic regulatory factor that is critical for MYC-mediated gene transcription.
High c-myc expression is associated with colorectal cancer.
Melatonin disturbs SUMOylation-mediated crosstalk between c-Myc and nestin (show NES Proteins) via MT1 (show MT1A Proteins) activation and promotes the sensitivity of paclitaxel in brain cancer stem cells.
FBP1 (show FBP1 Proteins) modulates the sensitivity of pancreatic cancer cells to BET inhibitors by decreasing the expression of c-Myc. These findings highlight FBP1 (show FBP1 Proteins) could be used as a therapeutic niche for patient-tailored therapies
miR135a directly bound to UCA1 and the 3' untranslated region of cmyc, and UCA1 competed with cmyc for miR135a binding.
MYC directly regulates DANCR and plays important role in cancer cell proliferation.
In this review, we provide support to the hypothesis that the cooperation of c-Myc with transcriptional cofactors mediates c-Myc-induced cellular functions. We produce evidence that recently identified cofactors are involved in c-Myc control of survival mechanisms of cancer cells
4-chlorobenzoyl berbamine (CBBM (show OPN1MW Proteins)) inhibits the JAK2 (show JAK2 Proteins)/STAT3 (show STAT3 Proteins) pathway, leading to reduced c-Myc transcription. Collectively, these findings suggest that CBBM (show OPN1MW Proteins) could be a promising lead compound for treatment of c-Myc-driven diffuse large B cell lymphoma.
Results revealed that C-MYC protein is highly expressed in colon cancer tissues, mainly in the cell nucleus and was identified as a direct target for mir (show MLXIP Proteins)-184. C-MYC appeared to participate in cell cycle regulation and malignant transformation to colon cancer.
MACC1 (show MACC1 Proteins) and c-Myc are highly expressed in serum and tumor tissues of EC patients. Both are correlated with TNM (show ODZ1 Proteins) stage, primary infiltration, and lymph node or distal metastasis.

Cow (Bovine) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

Ouabain-induced proliferation might be attributed, at least in part, to decrease of intracellular free calcium and increase of c-myc mRNA expression, and that may be directly or indirectly involved in regulation of blood pressure.

Rabbit V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

report the isolation of complete coding regions of rabbit SOX2, KLF4, C-MYC and NANOG, which encode transcription factors that play crucial regulatory roles during early mammalian embryonic development

Mouse (Murine) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

c-Myc is essential for tumor initiation, maintenance, and metastasis.
Genomic characterization of Emu-Myc mouse lymphomas identifies Bcor (show BCOR Proteins) as a Myc cooperative tumor-suppressor gene.
The data supports an indispensable role for Mule in cardiac homeostasis through the regulation of mitochondrial function via maintenance of Pgc-1alpha and Pink1 (show PINK1 Proteins) expression and persistent negative regulation of c-Myc.
MYC binding is enriched at neuroendocrine genes in tumor cells and loss of MYC reduces ductal-neuroendocrine lineage heterogeneity, while deregulated MYC expression in KRAS mutants increases this phenotype.
Although either BCR (show BCR Proteins) or CD40 (show CD40 Proteins) ligation induced c-Myc in naive B cells, both signals were required to highly induce c-Myc, a critical mediator of GC B (show NPR2 Proteins) cell survival and cell cycle reentry.
Myc is a component that links neuromesodermal progenitors maintenance and pre-somitic mesoderm maturation during the body axis elongation stages of mouse embryogenesis.
Myc potentiates the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signalling pathway, which cooperates with the transcriptional regulatory network in sustaining embryonic stem cell self-renewal.
Although mnt heterozygosity clearly slowed lymphomagenesis in vavP-MYC10 and Emu-myc mice, the change(s) in cellular properties responsible for this effect remain to be identified.
clusters of enhancers, such as BENC in the myc gene, form highly combinatorial systems that allow precise control of gene expression across normal cellular hierarchies and which also can be hijacked in malignancies
Conditional deletion of Myc in hyaloid vascular endothelial cells suppressed both proliferation and cell death.

Zebrafish V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

Methylparabens exposure increased malformations, LPO, apoptosis, ccnd1 and myca expressions, and decreased GST activities and NO levels compared with the control group.
Apoptosis was also observed with myca expression; introduction of homozygous tp53 (show TP53 Proteins)(-/-) mutation into the myca transgenic fish reduced apoptosis and accelerated tumor progression.
MYC down-regulation induces mitochondrial apoptosis in T lymphoblasts.

Xenopus laevis V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

These findings not only reveal a novel role of Mad1 (show MXD1 Proteins) in regulating developmental cell death but also suggest that a balance of Mad and Myc controls cell fate determination during adult organ development.
Thyroid hormone (show PTH Proteins) activates protein arginine methyltransferase 1 expression by directly inducing c-Myc transcription during Xenopus intestinal stem cell development.(
c-Myc has a direct role in the control of DNA replication
Findings support a model in which Myc, Twist and Slug/Snail2 function in a regulatory circuit within lateral plate mesoderm that directs normal vessel formation in both the vascular and lymphatic systems.

Fruit Fly (Drosophila melanogaster) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

Expression of Drosophila Myc (dMyc) suppresses, whereas loss of dMyc enhances, ectopically activated JNK (show MAPK8 Proteins) signaling-induced cell death. dMyc impedes physiologically activated JNK (show MAPK8 Proteins) pathway-mediated cell death. Loss of dMyc triggers JNK (show MAPK8 Proteins) pathway activation and JNK (show MAPK8 Proteins)-dependent cell death.
tissue-specific downregulation of the Drosophila homolog of human c-myc proto-oncogene (dMyc) suppresses tau-mediated morphological and functional deficits by reducing abnormal tau hyperphosphorylation and restoring the heterochromatin loss.
dMyc has an essential role in preventing JNK (show MAPK8 Proteins)-mediated retinal glial activation
the key target of the Psi/MED network in controlling developmentally regulated tissue growth is the transcription factor MYC.
Myc dosage plays crucial role in determining sex-specific size in Drosophila larvae and adult tissue. Double dose of Myc in females serves at least twice in development to promote sexual size dimorphism.
BicC (show BICC1 Proteins) down regulates Myc in the Malpighian tubule.
activation of the TOR-Myc axis in midgut stem and progenitor cells influences a variety of traits in Drosophila
Drosophila adult muscle precursors display homing behavior to muscle niche and the niche-driven Insulin (show INS Proteins)-Notch (show NOTCH1 Proteins)-dMyc cascade plays a key role in setting the activated state of adult muscle precursors.
a functional link between Myc, a renowned oncogene (show RAB1A Proteins), and the essential nucleotide biosynthetic enzyme CTPsyn.
MYC and S6K (show RPS6KB1 Proteins) cooperate through coordinate activation of the essential Pol I transcription initiation factor TIF-1A (show RRN3 Proteins).

C-MYC (MYC) Protein Profile

Protein Summary

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Alternative names and synonyms associated with C-MYC (MYC)

MYC proto-oncogene, bHLH transcription factor (MYC)
v-myc myelocytomatosis viral oncogene homolog (LOC100136746)
MYC proto-oncogene, bHLH transcription factor (Myc)
myelocytomatosis oncogene (Myc)
MYC proto-oncogene, bHLH transcription factor a (myca)
MYC proto-oncogene, bHLH transcription factor L homeolog (myc.L)
v-myc myelocytomatosis viral oncogene homolog (avian) (MYC)
CG10798 gene product from transcript CG10798-RB (Myc)

anon-WO03040301.171 protein
AU016757 protein
bHLHe39 protein
bHLHe57 protein
c-MYC protein
c-myc II protein
CG10798 protein
CMyc protein
d-myc protein
da protein
dm protein
dm/dMyc protein
dm/myc protein
Dmel\CG10798 protein
dmyc protein
dmyc1 protein
EG:BACN5I9.1 protein
l(1)G0139 protein
l(1)G0354 protein
l(1)G0359 protein
LOC100136746 protein
mMyc protein
MRTL protein
myc protein
myc-B protein
myc2 protein
MYCC protein
Niard protein
Nird protein
RNCMYC protein
zc-myc protein

Protein level used designations for MYC

, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , avian myelocytomatosis viral oncogene homolog class E basic helix-loop-helix protein 39 myc proto-oncogene protein myc-related translation/localization regulatory factor proto-oncogene c-Myc transcription factor p64 v-myc myelocytomatosis viral oncogene homolog c-myc proto-oncogene avian myelocytomatosis viral (v-myc) oncogene homolog c-Myc Avian myelocytomatosis viral (v-myc) oncogene homolog myelocytomatosis viral oncogene homolog v-myc avian myelocytomatosis viral oncogene homolog cellular myelocytomatosis oncogene Proto-oncogene c-Myc Transcription factor p64 C-Myc1 c-Myc-A cmyca transcriptional regulator Myc-A MYC II transcriptional regulator Myc-B Myc proto-oncogene protein CG10798 gene product from transcript CG10798-RB CG10798-PA CG10798-PB Diminutive protein Myc-PA Myc-PB dMyc1 diminuitive diminutive lethal (1) G0354 lethal (1) G0359

GENE ID	SPECIES
4609	Homo sapiens
464393	Pan troglodytes
403924	Canis lupus familiaris
511077	Bos taurus
448810	Sus scrofa
420332	Gallus gallus
100327265	Oryctolagus cuniculus
100136746	Oncorhynchus mykiss
24577	Rattus norvegicus
443447	Ovis aries
17869	Mus musculus
694626	Macaca mulatta
100379628	Felis catus
30686	Danio rerio
399315	Xenopus laevis
100407754	Callithrix jacchus
100972175	Pan paniscus
100724557	Cavia porcellus
31310	Drosophila melanogaster

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Show all V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) Proteins (MYC) with Pubmed References