CHEK2 ELISA Kit

15 products by 5 suppliers: Assay Biotechnology | Aviva Systems Biology | EIAab | RayBiotech | Abnova
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CHEK2 ELISA Kit
$480.00
96 tests
Human
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CHEK2 ELISA Kit
$480.00
96 tests
Mouse (Murine)
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CHEK2 ELISA Kit
$480.00
96 tests
Rat (Rattus)
Recommendations are based on data provided indicating:
  • ELISA Kit Sensitivity
    The recommended ELISA Kit will likely detect the antigen better in the approved sample types than the available alternatives.
  • ELISA Kit Specificity
    The recommended ELISA Kit will likely detect the antigen in question with higher specificity in approved samples than the available alternatives.
  • Experiement Reproducibility
    The results will be likely more reproducible, with high inter- or intra-assay CV and Recovery (for values within the std curve) than the available alternatives.
  • ELISA Kit Robustness
    The recommended assay will likely function better with approved sample types, and will not suffer from undue matrix interference than the available alternatives.
Picking recommended ELISA Kits will save you time - yet all 15 products covered by our Money Back Guarantee!
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Relevance Score uniqeid Catalogue Id Detection Method Sample Type Analytical Method Detection Range Sensitivity Supplier References Quantity Price
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Log in to see
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Relevance Score uniqeid Catalogue Id Detection Method Sample Type Analytical Method Detection Range Sensitivity Supplier References Quantity Price
6 element-ABIN1380544 ABIN1380544 Colorimetric
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Cell Culture Cells Qualitative Cell ELISA Log in to see
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6 element-ABIN1380343 ABIN1380343 Colorimetric
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6 element-ABIN2114893 ABIN2114893 Colorimetric
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6 element-ABIN2114895 ABIN2114895 Colorimetric
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2 x 96 tests $597.40
6 element-ABIN2114892 ABIN2114892 Colorimetric
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2 x 96 tests $597.40
6 element-ABIN2114891 ABIN2114891 Colorimetric
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6 element-ABIN2683809 ABIN2683809 Colorimetric
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1 kit $714.29

CHEK2 Antigen Profile

Antigen Summary

In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors. This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CHEK2

  • checkpoint kinase 2 (CHEK2) ELISA Kit
  • checkpoint kinase 2 (chek2) ELISA Kit
  • checkpoint kinase 2 (Chek2) ELISA Kit
  • serine/threonine-protein kinase chk2 (MCYG_07308) ELISA Kit
  • blue sensitive cone opsin (OPN2SW) ELISA Kit
  • CDS1 ELISA Kit
  • CHK2 ELISA Kit
  • HuCds1 ELISA Kit
  • LFS2 ELISA Kit
  • PP1425 ELISA Kit
  • RAD53 ELISA Kit
  • hCds1 ELISA Kit
  • fa66f08 ELISA Kit
  • wu:fa66f08 ELISA Kit
  • zgc:55865 ELISA Kit
  • Cds1 ELISA Kit
  • HUCDS1 ELISA Kit
  • Rad53 ELISA Kit
  • Chk2 ELISA Kit
  • CHK-2 ELISA Kit

Protein level used designations for CHEK2

CHK2 checkpoint homolog , cds1 homolog , checkpoint-like protein CHK2 , serine/threonine-protein kinase Chk2 , protein kinase CHK2 , checkpoint and tumor suppressor protein 2 , Cds1 homolog , Rad53 homolog , protein kinase Chk2 , CHK2 checkpoint homolog (S. pombe) , serine/threonine-protein kinase Chk2-like , serine/threonine-protein kinase chk2 , blue cone photoreceptor pigment , blue-sensitive opsin , opsin CHK-2

GENE ID SPECIES
11200 Homo sapiens
486338 Canis lupus familiaris
458733 Pan troglodytes
100192447 Sus scrofa
336998 Danio rerio
768913 Gallus gallus
50883 Mus musculus
114212 Rattus norvegicus
100059288 Equus caballus
100404949 Callithrix jacchus
100467146 Ailuropoda melanoleuca
100594542 Nomascus leucogenys
9226831 Arthroderma otae CBS 113480
396525 Gallus gallus
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