Browse our anti-NFKB1 (NFKB1) Antibodies

Human Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

1. inflammatory markers IL8 and NFKB are reduced in human cells in a process mediated by branched-chain fatty acid vernix-monoacylglycerides

2. High NF-kappa-B expression is associated with glioblastoma growth.

3. NFKB1single nucleotide polymorphism rs28362491 was associated with an increased risk of susceptibility to hepatitis C in the Chinese Han population.

4. The study results suggest that NFKB1 ins/ins genotype of SNP rs28362491 is linked to morbid obesity with high-level of liver enzymes

5. Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-kappaB and p53 signaling pathways

6. TRAIL-induced activation of DcR2 led to increased NF-kappaB activation in large granular lymphocyte leukemia.

7. Nuclear factor kappa B subunit 1 (NFKB1) is significantly increased in psoriasis patients.

8. NFKB1 -94ins/delATTG and TLR4Asp299Gly polymorphisms are associated with increased glioma cancer risk in a Turkish population

9. The results suggest that cytokine-induced autophagy contributes to late-phase IkappaBalpha degradation, facilitates NF-kappaB nuclear translocation and VCAM-1 transcription for long-term VCAM-1 expression.

10. NF-kappa B inhibition abrogates TLR4-promoted catabolic and inflammatory responses in high glucose-treated chondrocytes.

11. The expression of SP and TRPV1 in intervertebral disc tissues in patients with Degenerative Disc Disease was associated with NF-kappaB activation.

12. Hyperbaric oxygen therapy therapy regulated the inflammatory reaction in secondary spinal cord injury by decreasing plasma HMGB1/NF-kappaB levels and reducing the dispersion of electromyogram F-waves of the lower limbs, thereby promoting neurological function recovery.

13. the interaction of TRAF6 with c-Cbl causes lysine 48-linked polyubiquitination for both negative feedback regulation and signaling cross-talk between RANKL and IFN-gamma.

14. Exosomal FMR1-AS1 facilitates maintaining cancer stem-like cell dynamic equilibrium via TLR7/NF-kappaB/c-Myc signaling in female esophageal carcinoma.

15. It is an important transcriptional regulator of angiogenesis. Thus, inhibition of NF-kappaB may suppress the development of periapical lesions via blockage of angiogenesis.

16. NFkappaB signaling role in the regulation of pro-inflammatory cytokines during TH17 responses.

17. independent putative primary functional variants in NFKB1/MANBA and showed the distinct molecular mechanism by which each putative primary functional variant conferred susceptibility to Primary biliary cholangitis, were identified.

18. High NFKappa B expression is associated with lymph node metastasis and intrahepatic metastasis in Gallbladder Cancer.

19. NF-kappaB role in the intrahepatic cholestasis of pregnancy.

20. brazilin effectively attenuates catabolic processes in human osteoarthritic cartilage and chondrocytes - at least in part due to the inhibition of NFKB1/p50-which indicates a chondroprotective potential of brazilin in osteoarthritis

Cow (Bovine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

1. These results indicated that docosahexaenoic acid may attenuate lipopolysaccharide-stimulated inflammatory response in bovine mammary epithelial cells by suppressing NF-kappaB activation through a mechanism partly dependent on PPARgamma activation.

2. Taken together, Staphylococcus aureus induces TGF-beta1 and bFGF expression through the activation of AP-1 and NF-kappaB in bovine mammary gland fibroblasts.

3. Data indicate the involvement of PKC-alpha in proMMP-2 activation and inhibition of TIMP-2 expression by NF-kappaB-MT1-MMP-dependent and -independent pathway.

4. MMP-1 promotes VEGFR2 expression and proliferation of endothelial cells through stimulation of PAR-1 and activation of NF-kappaB

5. dynamic compression stimulates cell proliferation and proteoglycan synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 signalling pathways

Rhesus Monkey Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

1. TRIM5alpha represses HIV-1 LTR promoter activity by negatively regulating TAK1/TAB1/TAB2/TAB3-complex-mediated NF-kappaB activation.

Pig (Porcine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

1. Actinobacillus pleuropneumoniae induces alveolar Macrophages to produce proinflammatory cytokines via upregulation of TLR4 and NF-kappaB.

2. Here, heat shock protein 27 (Hsp27) has been identified as a novel binding partner of NS5A, a protein functioning in classical swine fever virus genome replication. Further findings clearly demonstrate that the inhibition of viral replication by Hsp27 is mediated via the NF-kappaB signaling pathway.

3. Porcine parvovirus virus infection significantly induced IL-6 expression and this induction depended on NF-kappaB activation and TLR9 signaling pathways in PK-15 cell.

4. This study showed that porcine epidemic diarrhea virus inhibited NF-kappaB activity and nsp1 was a potent NF-kappaB antagonist for suppression of both interferon and early production of pro-inflammatory cytokines.

5. inhibition of NF-kappaB increases autophagy via JNK signaling, and promotes steroidogenesis in porcine granulosa cells

6. SIRT1, p53 and NF-kappaB are involved in the control of both the proliferation and the apoptosis of ovarian cells.

7. porcine CD74 significantly enhanced the inflammatory response by regulating the NF-kappaB signalling pathway during PCV2 infection, which suggests that porcine CD74 may be implicated in the pathogenesis of PCV2 infection.

8. These results suggest that trans-10, cis-12-conjugated linoleic acid can modulate TNF-alpha production and NF-kappa B expression by a PPARgamma-dependent pathway in porcine peripheral blood mononuclear cells.

Mouse (Murine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

1. The findings of this study support that loss of NF-kappaB p50 function and aging in middle-aged mice may interact to excessively augment peripheral/microglial pro-inflammatory responses and point to a novel neuroinflammation signaling mechanism independent the NF-kappaB p50/p65 transcription factor in this process.

2. NF-kappa B inhibition abrogates TLR4-promoted catabolic and inflammatory responses in high glucose-treated chondrocytes.

3. the feedback loop of the "EMMPRIN/NF-kappaB" pathway plays an important role in atherosclerotic plaques via modulation of autophagy in macrophages.

4. Studied effect of Papaver nudicaule extract on reduction of inflammation through inactivating NF-kappaB and signal transducer and activator of transcription 3 (STAT3) in lipopolysaccharide treated RAW264.7 cells.

5. These results indicate the relevance of CX3CL1 in the activation of the pro-inflammatory NF-kappaB signalling pathway through MSK1 in microglial cells.

6. Data show that MiR-199a could regulate the activation of NF-kappa B (NF-kappaB) by directly targeting Klotho protein.

7. These results reveal the roles for NF-kappaB during different phases of neocortical gliogenesis and identify NF-kappaB as an inhibitor of early oligodendrocyte development in the cerebral cortex.

8. Furanodien-6-one from Commiphora erythraea inhibits the NF-kappaB signalling and attenuates LPS-induced neuroinflammation.

9. NF-KB p50 involvement in colorectal cancer development, through its engagement in the protumor activation of macrophages, identifies it as a candidate for prognostic and target therapeutic intervention.

10. MicroRNA-326 aggravates acute lung injury in septic shock by mediating the NF-kappaB signaling pathway via BCL2A1.

11. High NFKB1expression is associated with Osteoarthritis.

12. Reducing NF-kappaB activation attenuates PDLIM2 deficiency-exacerbated inflammation and dyslipidemia in Palmitate -treated primary hepatocytes.

13. Findings confirm that signalling through MyD88 is the primary driver for Lipopolysaccharide-dependent NF-kappaB translocation to the nucleus. The pattern of NF-kappaB dynamics in TRIF-deficient cells does not, however, directly reflect the kinetics of TNFalpha promoter activation, supporting the concept that TRIF-dependent signalling plays an important role in the transcription of this cytokine.

14. Chandipura virus infection triggered the activation of signalling pathways mediated by mitogen-activated protein kinases, including p38, JNK 1 and 2, and nuclear factor kappaB.

15. These findings provide mechanistic insight into how polymorphisms that attenuate NFKB1 expression predispose humans to epithelial cancers, highlighting the pro-tumorigenic activity of STAT1 and identifying targetable vulnerabilities in GC.

16. Macrophage-derived IL1B/NF-kappaB signaling mediates parenteral nutrition-associated cholestasis in a mouse model.

17. SIRT1 upregulation protects against liver injury induced by a HFD through inhibiting CD36 and the NF-kappaB pathway in mouse Kupffer cells.

18. activation of NF-kappaB pathway is essential for Bacterial lipoprotein tolerance-augmented antimicrobial activity in innate phagocytes and depends primarily on both NOD1 and NOD2.

19. High host NF-kappaB p50 induces murine glioblastoma tumor.

20. NF-kappaB is responsible for Morgana dependent metastasis.

Zebrafish Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

1. Study indicate an essential role of NF-kappaB in gonadal differentiation.