Browse our anti-NFKB1 (NFKB1) Antibodies

Human Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

1. In addition to inducing NF-kappaB, lymphotoxin-alpha promotes JAK2/STAT6 signaling.

2. SM22alpha reduction in abdominal aortic aneurysms ( AAAs) because of the SM22alpha promoter hypermethylation accelerates AAA formation through the reactive oxygen species/NF-kappaB pathway.

3. Data show that miR-29a-3p participates in the hepatocellular carcinoma (HCC) progression by regulation of NF-kappa-B (NF-kappaB) pathway.

4. High NF-kB expression is associated with radio-resistance of docetaxel-resistant Lung Adenocarcinoma.

5. LncRNA PCAT1 activates AKT and NF-kappaB signaling in castration-resistant prostate cancer by regulating the PHLPP/FKBP51/IKKalpha complex.

6. FGD5-AS1/miR-142-3p/SOCS6 axis may act as an important indicator

7. RNF25 plays an essential role in gefitinib resistance of Non-small cell lung cancer by mediating cross-talk between NF-kappaB and ERK pathways.

8. Molecular docking analysis showed that Wi-A did not disrupt; however, decreased the stability of the NFkappaB-DNA complex. It was supported by downregulation of DNA-binding and transcriptional activities of NFkappaB.

9. Investigated the role of neddylation in collagen-induced arthritis (CIA); found TNF receptor-associated factor 6 (TRAF6) neddylation at Lys124 was essential for IL-17A-induced NF-kappaB activation in inflammatory arthritis.

10. ERK/NF- kappa B signaling pathway has a role in the inhibition of tumor growth by amentoflavone in glioblastoma.

11. preliminary findings suggest that the haplotype of rs28362491 and rs72696119 in NFKB1 could act as a novel genetic marker to predict oral cancer risk in the southeast of China

12. These findings showed that the role of NF-kappaB1 in humans could be critical for the development of acquired and innate immunity and further highlights the role of human T cells in anti-mycobacterial immunity.

13. Co-expression of p65 and phosphorylated p105 but not of either p65 or phosphorylated p105 alone was associated with a poor prognosis in surgically resectable non-small cell lung cancer patients.

14. PRDX1 negatively regulates TLR4 signaling for NFKB activation and autophagy functions such as bactericidal activity, cancer cell migration, and cancer cell invasion by inhibiting TRAF6 ubiquitin-ligase activity.

15. INHA inhibits BMP9-induced osteogenic differentiation through blocking BMP/Smad signal and activating NF-kappaB signal in mesenchymal stem cells.

16. In conclusion, the authors suggest that NF-kappaB is capable of enhancing the expression of PCT by either directly activating the transcription of the PCT gene or indirectly modulating the expression of its regulatory component, miR-513b.

17. The role of the lncRNA FLJ46906 in the aging process via aging associated genes regulated by NF-kappaB and AP-1.

18. The expression of NF-kappaB is increased in intervertebral disc tissue in patients with disc herniation.

19. These findings identify a previously unrecognized role of SKP2 in NF-kappaB activation by which SKP2 acts as a secondary receptor to assist IKKbeta delivery to autophagosomes for degradation in a p62-dependent manner.

20. We show that heterozygous loss-of-function variants in NFKB1 are the most common known monogenic cause of CVID, which results in a temporally progressive defect in the formation of immunoglobulin-producing B cells.

Cow (Bovine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

1. These results indicated that docosahexaenoic acid may attenuate lipopolysaccharide-stimulated inflammatory response in bovine mammary epithelial cells by suppressing NF-kappaB activation through a mechanism partly dependent on PPARgamma activation.

2. Taken together, Staphylococcus aureus induces TGF-beta1 and bFGF expression through the activation of AP-1 and NF-kappaB in bovine mammary gland fibroblasts.

3. Data indicate the involvement of PKC-alpha in proMMP-2 activation and inhibition of TIMP-2 expression by NF-kappaB-MT1-MMP-dependent and -independent pathway.

4. MMP-1 promotes VEGFR2 expression and proliferation of endothelial cells through stimulation of PAR-1 and activation of NF-kappaB

5. dynamic compression stimulates cell proliferation and proteoglycan synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 signalling pathways

Rhesus Monkey Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

1. TRIM5alpha represses HIV-1 LTR promoter activity by negatively regulating TAK1/TAB1/TAB2/TAB3-complex-mediated NF-kappaB activation.

Pig (Porcine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

1. endotracheal tube presence was characterized by neutrophil activation, necrosis, and release of proinflammatory cytokines mediated by TLR9/NF-kappaB induction.

2. Actinobacillus pleuropneumoniae induces alveolar Macrophages to produce proinflammatory cytokines via upregulation of TLR4 and NF-kappaB.

3. Here, heat shock protein 27 (Hsp27) has been identified as a novel binding partner of NS5A, a protein functioning in classical swine fever virus genome replication. Further findings clearly demonstrate that the inhibition of viral replication by Hsp27 is mediated via the NF-kappaB signaling pathway.

4. Porcine parvovirus virus infection significantly induced IL-6 expression and this induction depended on NF-kappaB activation and TLR9 signaling pathways in PK-15 cell.

5. This study showed that porcine epidemic diarrhea virus inhibited NF-kappaB activity and nsp1 was a potent NF-kappaB antagonist for suppression of both interferon and early production of pro-inflammatory cytokines.

6. inhibition of NF-kappaB increases autophagy via JNK signaling, and promotes steroidogenesis in porcine granulosa cells

7. SIRT1, p53 and NF-kappaB are involved in the control of both the proliferation and the apoptosis of ovarian cells.

8. porcine CD74 significantly enhanced the inflammatory response by regulating the NF-kappaB signalling pathway during PCV2 infection, which suggests that porcine CD74 may be implicated in the pathogenesis of PCV2 infection.

9. These results suggest that trans-10, cis-12-conjugated linoleic acid can modulate TNF-alpha production and NF-kappa B expression by a PPARgamma-dependent pathway in porcine peripheral blood mononuclear cells.

Mouse (Murine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

1. The restoration of microglial homeostatic density requires NF-kappaB signaling as well as apoptotic egress of excessive cells.

2. NF-kappaB plays an important role in the transcriptional activation of estrogen-ERalpha stimulated TRPV5 expression to inhibit bone resorption and osteoclastogenesis.

3. RANKL expression is dependent on NFKB in a mouse model of immature T-cell leukemia

4. the PI3K/Akt-Beclin1 signaling pathway positively regulates phagocytosis and negatively mediates NF-kappaB-dependent inflammation in S. aureus-infected macrophages

5. Parkin modulates the lysine 63 ubiquitination status of RIPK1 to promote the activation of NF-kappaB and MAPKs.

6. Reduced susceptibility to diet-induced obesity and dyslipidemia in p50(-/-) mice results from an increase in metabolic rate.

7. NF-kappaB participated in the hepatocellular carcinoma suppressor function of Ndrg2-deficient macrophages.

8. TLR3-NFkappaB pathway is necessary for the maturation of committed precursors into mature cardiomyocytes.

9. The findings of this study support that loss of NF-kappaB p50 function and aging in middle-aged mice may interact to excessively augment peripheral/microglial pro-inflammatory responses and point to a novel neuroinflammation signaling mechanism independent the NF-kappaB p50/p65 transcription factor in this process.

10. NF-kappa B inhibition abrogates TLR4-promoted catabolic and inflammatory responses in high glucose-treated chondrocytes.

11. the feedback loop of the "EMMPRIN/NF-kappaB" pathway plays an important role in atherosclerotic plaques via modulation of autophagy in macrophages.

12. Studied effect of Papaver nudicaule extract on reduction of inflammation through inactivating NF-kappaB and signal transducer and activator of transcription 3 (STAT3) in lipopolysaccharide treated RAW264.7 cells.

13. These results indicate the relevance of CX3CL1 in the activation of the pro-inflammatory NF-kappaB signalling pathway through MSK1 in microglial cells.

14. Data show that MiR-199a could regulate the activation of NF-kappa B (NF-kappaB) by directly targeting Klotho protein.

15. These results reveal the roles for NF-kappaB during different phases of neocortical gliogenesis and identify NF-kappaB as an inhibitor of early oligodendrocyte development in the cerebral cortex.

16. NF-KB p50 involvement in colorectal cancer development, through its engagement in the protumor activation of macrophages, identifies it as a candidate for prognostic and target therapeutic intervention.

17. MicroRNA-326 aggravates acute lung injury in septic shock by mediating the NF-kappaB signaling pathway via BCL2A1.

18. High NFKB1expression is associated with Osteoarthritis.

19. Reducing NF-kappaB activation attenuates PDLIM2 deficiency-exacerbated inflammation and dyslipidemia in Palmitate -treated primary hepatocytes.

20. Findings confirm that signalling through MyD88 is the primary driver for Lipopolysaccharide-dependent NF-kappaB translocation to the nucleus. The pattern of NF-kappaB dynamics in TRIF-deficient cells does not, however, directly reflect the kinetics of TNFalpha promoter activation, supporting the concept that TRIF-dependent signalling plays an important role in the transcription of this cytokine.

Zebrafish Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

1. Study indicate an essential role of NF-kappaB in gonadal differentiation.