Browse our anti-p300 (EP300) Antibodies

Full name:: anti-E1A Binding Protein P300 Antibodies (EP300)

On www.antibodies-online.com are 275 E1A Binding Protein P300 (EP300) Antibodies from 22 different suppliers available. Additionally we are shipping p300 Kits (18) and p300 Proteins (9) and many more products for this protein. A total of 318 p300 products are currently listed.

Synonyms:: A430090G16, A730011L11, KAT3B, p300, p300 HAT, RSTS2

list all antibodies	Gene Name	GeneID	UniProt
	EP300	2033	Q09472
	EP300	328572
	EP300	170915
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Top referenced anti-p300 Antibodies

Human Monoclonal p300 Primary Antibody for ChIP, EM - ABIN152047 : Eckner, Ludlow, Lill, Oldread, Arany, Modjtahedi, DeCaprio, Livingston, Morgan: Association of p300 and CBP with simian virus 40 large T antigen. in Molecular and cellular biology 1996 (PubMed)
Show all 8 Pubmed References
Human Monoclonal p300 Primary Antibody for FACS, ICC - ABIN151948 : Eckner, Yao, Oldread, Livingston: Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. in Genes & development 1996 (PubMed)
Show all 5 Pubmed References
Human Polyclonal p300 Primary Antibody for DB - ABIN1881299 : Zhang, Zhang, Rui, Liu: p300-mediated acetylation stabilizes the Th-inducing POK factor. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
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Human Monoclonal p300 Primary Antibody for ChIP, ICC - ABIN152048 : Eckner, Ewen, Newsome, Gerdes, DeCaprio, Lawrence, Livingston: Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. in Genes & development 1994 (PubMed)
Show all 4 Pubmed References
Human Polyclonal p300 Primary Antibody for ChIP, ICC - ABIN152981 : Julien, Carriere, Moreau, Roux: mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling. in Molecular and cellular biology 2010 (PubMed)
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Human Monoclonal p300 Primary Antibody for ChIPSeq, ChIP - ABIN2668569 : Dallas, Yaciuk, Moran: Characterization of monoclonal antibodies raised against p300: both p300 and CBP are present in intracellular TBP complexes. in Journal of virology 1997 (PubMed)
Show all 3 Pubmed References
Human Monoclonal p300 Primary Antibody for ELISA, WB - ABIN966068 : Stauffer, Chang, Huang, Dunn, Thayer: p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint. in The Journal of biological chemistry 2007 (PubMed)
Show all 2 Pubmed References
Human Monoclonal p300 Primary Antibody for ELISA, WB - ABIN969098 : Geiger, Sharma, Kim, Nyborg: The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB. in Molecular and cellular biology 2008 (PubMed)
Show all 2 Pubmed References
Human Monoclonal p300 Primary Antibody for IP, WB - ABIN967440 : Rikitake, Moran: DNA-binding properties of the E1A-associated 300-kilodalton protein. in Molecular and cellular biology 1992 (PubMed)
Show all 3 Pubmed References
Human Polyclonal p300 Primary Antibody for IHC, IP - ABIN152980 : Zhang, Vogel, Liu, Topark-Ngarm, Arbogast, Maier, Filtz, Leid: Coordinated regulation of transcription factor Bcl11b activity in thymocytes by the mitogen-activated protein kinase (MAPK) pathways and protein sumoylation. in The Journal of biological chemistry 2012 (PubMed)

More Antibodies against p300 Interaction Partners

Human E1A Binding Protein P300 (EP300) interaction partners

Study suggest that both p300 and CREB (show CREB1 Antibodies) are required for the function integrity of HIF-1alpha (show HIF1A Antibodies) transcription machinery and subsequent angiogenesis, suggesting future studies to improve burn wound healing might be directed to optimization of the interaction between p300, CREB (show CREB1 Antibodies) and HIF-1alpha (show HIF1A Antibodies).
These results suggest that EP300 harbors adaptive variants in Tibetans, which might contribute to high-altitude adaptation through regulating NO production.
EP300 plays a major role in the reprogramming events, leading to a more malignant phenotype with the acquisition of drug resistance and cell plasticity, a characteristic of metaplastic breast cancer.
E-cadherin (show CDH1 Antibodies) expression was increased by transfection of p300 small interfering RNA in a dose-dependent manner.. There was a correlation between Snail (show SNAI1 Antibodies) and p300 expressions in lung cancer. Moreover, p300 acetylates Snail (show SNAI1 Antibodies) both in vivo and in vitro, and K187 may be involved in this modification.
Two possible modes of pioneering associated with combinations of H2A.Z (show H2AFZ Antibodies) and p300/CBP (show CREBBP Antibodies) at nucleosome-occupied enhancers.
these results demonstrate that the reversible acetylation of FOXM1 (show FOXM1 Antibodies) by p300/CBP (show CREBBP Antibodies) and SIRT1 (show SIRT1 Antibodies) modulates its transactivation function
Ectopic expression of EP300-ZNF384 (show ZNF384 Antibodies) and CREBBP (show CREBBP Antibodies)-ZNF384 (show ZNF384 Antibodies) fusion altered differentiation of mouse hematopoietic stem and progenitor cells and also potentiated oncogenic transformation in vitro.our results indicate that gene fusion is a common class of genomic abnormalities in childhood ALL and that recurrent translocations involving EP300 and CREBBP (show CREBBP Antibodies) may cause epigenetic deregulation with potential for therapeutic targeting.
p300 inhibition attenuates both thrombin (show F2 Antibodies) induced-CCL2 (show CCL2 Antibodies) expression and histone H3 (show HIST3H3 Antibodies) and H4 acetylation in HLFs, suggesting that p300 is involved in thrombin (show F2 Antibodies)-induced CCL2 (show CCL2 Antibodies) expression via hyperacetylating histone H3 (show HIST3H3 Antibodies) and H4.
p300-dependent histone H3 (show HIST3H3 Antibodies) acetylation and C/EBPbeta (show CEBPB Antibodies)-regulated IKKbeta (show IKBKB Antibodies) expression contribute to thrombin (show F2 Antibodies)-induced IL-8/CXCL8 (show IL8 Antibodies) expression in human lung epithelial cells.
MnTE-2-PyP (show PPA1 Antibodies) decreased p300 complex binding to a specific HRE motif within the PAI-1 (show SERPINE1 Antibodies) gene promoter region, suppressed H3K9 acetylation, and consequently, repressed PAI-1 (show SERPINE1 Antibodies) expression. Mechanistically, less p300 transcriptional complex binding is not due to the reduction of binding between p300 and HIF-1 (show HIF1A Antibodies)/CREB (show CREB1 Antibodies) transcription factors, but through inhibiting the binding of HIF-1 (show HIF1A Antibodies)/CREB (show CREB1 Antibodies) transcription factors to DNA

Mouse (Murine) E1A Binding Protein P300 (EP300) interaction partners

Here the authors report a lipopolysaccharide-induced NFkappaB enhanceosome in which TonEBP (show NFAT5 Antibodies) is required for the recruitment of p300 (show NOTCH1 Antibodies). Increased expression of TonEBP (show NFAT5 Antibodies) enhances the NFkappaB activity and reduced TonEBP (show NFAT5 Antibodies) expression lowers it.
Enhancer-priming by MLL3/MLL4 (show MLL4 Antibodies) followed by enhancer-activation by CBP/p300 (show CREBBP Antibodies) sequentially shape dynamic enhancer landscapes during cell differentiation
Data show that LPS (show TLR4 Antibodies) induces endoplasmic reticulum (ER) stress and P300 (show NOTCH1 Antibodies) activity via the XBP1 (show XBP1 Antibodies)/IRE1 (show ERN1 Antibodies) pathway.
Loss of p300 (show NOTCH1 Antibodies) expression is associated with leukemogenesis.
UTX (show KDM6A Antibodies)-MLL4 (show MLL4 Antibodies)-p300 (show NOTCH1 Antibodies) transcriptional regulatory network establishing an "active enhancer landscape" and defines a detailed mechanism for the joint deposition of H3K4me1 and H3K27ac.
Acetylation-dependent control of global poly(A) RNA degradation by CBP/p300 (show CREBBP Antibodies) and HDAC1-HDAC2 (show HDAC1 Antibodies) has been described.
Data, including data from studies in cells from knockout mice, suggest that Prmt1 (show PRMT1 Antibodies) activity was necessary for c-Myc (show MYC Antibodies) binding to acetyltransferase p300 (show NOTCH1 Antibodies) in myeloid cells; Prmt1 (show PRMT1 Antibodies) inhibition decreases p300 (show NOTCH1 Antibodies) recruitment to c-Myc (show MYC Antibodies) target promoters and increased Hdac1 (show HDAC1 Antibodies) recruitment. [Prmt1 (show PRMT1 Antibodies), protein arginine N-methyltransferase 1 (show PRMT1 Antibodies); c-Myc (show MYC Antibodies) = Proto-Oncogene (show RAB1A Antibodies) Proteins c-myc (show MYC Antibodies); Hdac1 (show HDAC1 Antibodies) = histone deacetylase 1 (show HDAC1 Antibodies)]
In line with the acetyltransferase activity of p300 (show NOTCH1 Antibodies), H3K27 acetylation was reduced after HDACi and resulted in the formation of heterochromatin in the PTGES1 gene. In conclusion, HDAC (show HDAC3 Antibodies) activity maintains PTGES1 expression by recruiting p300 (show NOTCH1 Antibodies) to its gene
ARX positively regulates Wnt (show WNT2 Antibodies)/ beta-catenin (show CTNNB1 Antibodies) signaling and the C-terminal domain of ARX interacts with the armadillo (show PKP1 Antibodies) repeats in beta-catenin (show CTNNB1 Antibodies) to promote Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling. In addition, we found BCL9 (show BCL9 Antibodies) and P300 (show NOTCH1 Antibodies) also interact with ARX to modulate Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.
2-O, 3-O desulfated heparin inhibited HMGB1 (show HMGB1 Antibodies) release, at least in part, by direct molecular inhibition of p300 HAT activity.

p300 (EP300) Antigen Profile

Antigen Summary

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

Alternative names and synonyms associated with p300 (EP300)

E1A binding protein p300 (EP300) antibody
histone acetyltransferase p300 (LOC446056) antibody
E1A binding protein p300 (ep300) antibody
E1A binding protein p300 (Ep300) antibody

A430090G16 antibody
A730011L11 antibody
KAT3B antibody
p300 antibody
p300 HAT antibody
RSTS2 antibody

Protein level used designations for EP300

histone acetyltransferase p300 , histone acetyltransferase , E1A binding protein p300 , histone acetyltransferase p300-like , E1A-associated protein p300 , E1A-binding protein, 300kD , p300 HAT

GENE ID	SPECIES
100055626	Equus caballus
458862	Pan troglodytes
706258	Macaca mulatta
446056	Takifugu rubripes
100028102	Monodelphis domestica
100455260	Pongo abelii
100468694	Ailuropoda melanoleuca
100543704	Meleagris gallopavo
100566746	Anolis carolinensis
2033	Homo sapiens
328572	Mus musculus
418000	Gallus gallus
100684945	Canis lupus familiaris
100156226	Sus scrofa
170915	Rattus norvegicus
100734820	Cavia porcellus

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Show all anti-E1A Binding Protein P300 (EP300) Antibodies with Pubmed References

Human E1A Binding Protein P300 (EP300) interaction partners

Mouse (Murine) E1A Binding Protein P300 (EP300) interaction partners

Antigen Summary

Alternative names and synonyms associated with p300 (EP300)

Protein level used designations for EP300