PPM1D Proteins

7 Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) Proteins from 4 manufacturers are available on www.antibodies-online.com.

Data Quality
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Type
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    Protein
Antigen
  • 7
Reactivity
  • 6
  • 1
Application
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  • 4
  • 4
  • 2
  • 2
Host
  • 2
  • 2
  • 2
  • 1
Binding Specificity
  • 2
  • 2
  • 1
  • 1
Conjugate
  • 4
  • 2
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Protein Type
  • 7
Format
  • 4
7 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3086448
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3130585
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 90 % pure
ReactivityHuman
Application SDS
Order details Cat. No. ABIN5623952
$440.14
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1315909
$338.33
2 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1315910
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 90 % by SDS - PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN5854111
$553.85
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2729806
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
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PPM1D Protein Profile

Protein Summary

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The expression of this gene is induced in a p53-dependent manner in response to various environmental stresses. While being induced by tumor suppressor protein TP53/p53, this phosphatase negatively regulates the activity of p38 MAP kinase, MAPK/p38, through which it reduces the phosphorylation of p53, and in turn suppresses p53-mediated transcription and apoptosis. This phosphatase thus mediates a feedback regulation of p38-p53 signaling that contributes to growth inhibition and the suppression of stress induced apoptosis. This gene is located in a chromosomal region known to be amplified in breast cancer. The amplification of this gene has been detected in both breast cancer cell line and primary breast tumors, which suggests a role of this gene in cancer development.

Alternative names and synonyms associated with PPM1D

  • protein phosphatase, Mg2+/Mn2+ dependent 1D (PPM1D) antibody
  • protein phosphatase 1D magnesium-dependent, delta isoform (Ppm1d) antibody
  • protein phosphatase, Mg2+/Mn2+ dependent, 1D (Ppm1d) antibody
  • protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog (ppm1d.L) antibody
  • protein phosphatase, Mg2+/Mn2+ dependent, 1Da (ppm1da) antibody
  • AV338790 antibody
  • PP2C-DELTA antibody
  • ppm1d antibody
  • Wip1 antibody
  • wu:fj44c08 antibody
  • zgc:55836 antibody
  • zgc:77316 antibody

Protein level used designations for PPM1D

protein phosphatase 1D , protein phosphatase 1D magnesium-dependent, delta isoform , protein phosphatase 2C delta isoform , protein phosphatase Wip1 , wild-type p53-induced phosphatase 1 , PP2C-delta , p53-induced protein phosphatase 1 , protein phosphatase 2C isoform delta , protein phosphatase magnesium-dependent 1 delta , protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog , protein phosphatase, Mg2+/Mn2+ dependent, 1D , protein phosphatase 1D magnesium-dependent, delta

GENE ID SPECIES
8493 Homo sapiens
53892 Mus musculus
287585 Rattus norvegicus
417644 Gallus gallus
514005 Bos taurus
612934 Canis lupus familiaris
100525714 Sus scrofa
443988 Xenopus laevis
394065 Danio rerio
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