Browse our anti-RRM2B (RRM2B) Antibodies

Full name:: anti-Ribonucleotide Reductase M2 B (TP53 Inducible) Antibodies (RRM2B)

On www.antibodies-online.com are 90 Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) Antibodies from 24 different suppliers available. Additionally we are shipping RRM2B Proteins (6) and RRM2B Kits (2) and many more products for this protein. A total of 106 RRM2B products are currently listed.

Synonyms:: MTDPS8A, MTDPS8B, p53R2, RRM2B

list all antibodies	Gene Name	GeneID	UniProt
	RRM2B	50484	Q7LG56
	RRM2B	382985	Q6PEE3
	RRM2B	299976
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anti-Human RRM2B Antibodies:

anti-Mouse (Murine) RRM2B Antibodies:

anti-Rat (Rattus) RRM2B Antibodies:

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Top referenced anti-RRM2B Antibodies

Human Polyclonal RRM2B Primary Antibody for IHC - ABIN966974 : Tanaka, Arakawa, Yamaguchi, Shiraishi, Fukuda, Matsui, Takei, Nakamura: A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage. in Nature 2000 (PubMed)
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Human Polyclonal RRM2B Primary Antibody for IHC - ABIN966975 : Bechtel, Rosenfelder, Duda, Schmidt, Ernst, Wellenreuther, Mehrle, Schuster, Bahr, Blöcker, Heubner, Hoerlein, Michel, Wedler, Köhrer, Ottenwälder, Poustka, Wiemann, Schupp: The full-ORF clone resource of the German cDNA Consortium. in BMC genomics 2008 (PubMed)
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Human Monoclonal RRM2B Primary Antibody for IF, ELISA - ABIN565482 : Piao, Jin, Kim, Lee, Amatya, Hyun, Chang, You: Ribonucleotide reductase small subunit p53R2 suppresses MEK-ERK activity by binding to ERK kinase 2. in Oncogene 2009 (PubMed)
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More Antibodies against RRM2B Interaction Partners

Human Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) interaction partners

High RRM2B expression is associated with neoplasms.
Studied the expression of ribonucleotide reductase (RR) subunit p53R2 in nasopharyngeal carcinoma and its significance in the prognosis.
RRM1 (show RRM1 Antibodies)/RRM2B enzyme is capable of retaining activity in hypoxia and therefore is favored over RRM1 (show RRM1 Antibodies)/RRM2 (show RRM2 Antibodies) in order to preserve ongoing replication and avoid the accumulation of DNA damage in hypoxic cells.
p53R2 acts as a positive regulator of TrxR2 (show TXNRD2 Antibodies) activity in mitochondria both under normal physiological conditions and during the cellular response to DNA damage
Silencing of both PYCR1 (show PYCR1 Antibodies) and PYCR2 (show PYCR2 Antibodies) completely abolished anti-oxidation activity of RRM2B, demonstrating a functional collaboration of these metabolic enzymes in response to oxidative stress.
A newly discovered role of E2F1 (show E2F1 Antibodies) in the regulation of p53R2 expression in DNA damage response.
analysis of caspase (show CASP3 Antibodies)-dependent degradation of human R2 and p53R2 small subunits
in Turkish population p53R2 genotype distributions between head and neck squamous epithelial cell cancer patients and control groups were not statistically significantly different.
Data indicate that forkhead transcription factorsF OXO3 directly bound to and transcriptionally activated the promoter of ribonucleotide reductase subunit RRM2B, and induced the expression of RRM2B at RNA and protein levels.
we found no support of the hypothesis that aberrations of RRM1 (show RRM1 Antibodies) or RRM2B, neither individually nor in combination, are associated with an altered clinical outcome following chemotherapy.

Mouse (Murine) Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) interaction partners

Rrm2b plays a crucial role in maintaining chromosomal stability and preventing chronic-inflammation-associated tumorigenesis.
Rrm2b deficiency caused higher rates of spontaneous mutation in the kidneys of Rrm2b-/- mice. p53R2 has a pivotal role in maintaining dNTP levels for repair of DNA in resting cells.

RRM2B Antigen Profile

Antigen Summary

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with RRM2B

ribonucleotide reductase M2 B (TP53 inducible) S homeolog (rrm2b.S) antibody
ribonucleotide reductase regulatory TP53 inducible subunit M2B (RRM2B) antibody
ribonucleotide reductase M2 B (TP53 inducible) (rrm2b) antibody
ribonucleotide reductase M2 B (TP53 inducible) (Rrm2b) antibody
ribonucleotide reductase regulatory TP53 inducible subunit M2B (Rrm2b) antibody

MTDPS8A antibody
MTDPS8B antibody
p53R2 antibody
RRM2B antibody

Protein level used designations for RRM2B

ribonucleotide reductase M2 B (TP53 inducible) , ribonucleoside-diphosphate reductase subunit M2 B , TP53-inducible ribonucleotide reductase M2 B , p53-inducible ribonucleotide reductase small subunit 2 homolog , p53-inducible ribonucleotide reductase small subunit 2 short form beta , p53-inducible ribonucleotide reductase small subunit 2-like protein

GENE ID	SPECIES
379056	Xenopus laevis
420253	Gallus gallus
472832	Pan troglodytes
481988	Canis lupus familiaris
528960	Bos taurus
100062030	Equus caballus
100144925	Xenopus (Silurana) tropicalis
100172878	Pongo abelii
50484	Homo sapiens
382985	Mus musculus
299976	Rattus norvegicus

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Show all anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) Antibodies with Pubmed References

Human Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) interaction partners

Mouse (Murine) Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) interaction partners

Antigen Summary

Alternative names and synonyms associated with RRM2B

Protein level used designations for RRM2B