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anti-Rat (Rattus) INHBB Antibodies:
anti-Mouse (Murine) INHBB Antibodies:
anti-Human INHBB Antibodies:
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Human Polyclonal INHBB Primary Antibody for ELISA, WB - ABIN561500
Brozzetti, Alimohammadi, Morelli, Minarelli, Hallgren, Giordano, De Bellis, Perniola, Kämpe, Falorni: Autoantibody response against NALP5/MATER in primary ovarian insufficiency and in autoimmune Addison's disease. in The Journal of clinical endocrinology and metabolism 2015
The present study demonstrated that EGF (show EGF Antibodies) controlled expression of three activin (show Actbeta Antibodies) subunits (inhbaa (show INHBA Antibodies), inhbab and inhbb) in the follicle cells via diverse signaling pathways.
whereas the inhibitory effect of hCG (show CGA Antibodies) on activin betaB expression is likely mediated by PKA-independent pathway(s).
Activin (show Actbeta Antibodies) betaA is involved in promoting ovary and follicle growth, whereas activin betaB may have a tonic role throughout follicle development but becomes critical at the late stage of oocyte maturation and/or ovulation.
point mutation enhances the affinity of Noggin2 to ActivinB, while weakens its affinity to BMP.
Noggin2 protected the developing forebrain from inhibition by Activin B (show Actbeta Antibodies) and XWnt8 (show WNT8A Antibodies) signaling.
A new role for activin B (show Actbeta Antibodies) during gastrulation involves cell cycle arrest in the involuting dorsal axial mesoderm.
Used monoclonal antibody to xenopus laevis Inhbb in ELISA for detection of human Inhbb.
Inflammatory stimuli strongly induce Smad2 (show SMAD2 Antibodies) and Smad5 (show SMAD5 Antibodies) phosphorylation in wild-type mice. None of these Smad (show SMAD1 Antibodies) effectors are activated in mice deficient in activin B (show Actbeta Antibodies). Activin B (show Actbeta Antibodies), whose messenger RNA expression is strongly induced after LPS (show TLR4 Antibodies) administration or E coli infection, is required for activation of Smad1 (show SMAD1 Antibodies)/5/8 signaling. Hepcidin (show HAMP Antibodies) expression did not depend on activin B (show Actbeta Antibodies) expression.
These results suggest that prolonged exposure to hyperglycemia in the Ins2(Akita+/-) mice leads to progressive testicular disruption mediated by testicular activin (show Actbeta Antibodies) activity, rather than hormonal dysregulation.
This study tested the hypothesis that inhibins act in an autocrine manner on Leydig cells using a pre-pubertal Leydig cell line, TM3 (show TPM1 Antibodies), as a model of immature Leydig cells.
Menin binds on the promoter of Inhbb gene where it favours the recruitment of Ezh2 (show EZH2 Antibodies) via an indirect mechanism involving Akt (show AKT1 Antibodies)-phosphorylation.
Data suggest Inhbb is physiologically essential for early folliculogenesis; Inhbb appears to participate in regulation of cell cycle progression, apoptosis, and steroidogenesis (estradiol/progesterone synthesis) in ovarian granulosa cells in culture.
Activin B (show Actbeta Antibodies), a transforming growth factor beta - related ligand, is upregulated during tumorigenesis and drives the loss of insulin (show INS Antibodies) expression and beta-cell maturity in a mouse insulinoma (show RPS15 Antibodies) model.
in mammalian spinal cord, Tgfbeta (show TGFB1 Antibodies) ligands and ActB (show ACTB Antibodies) together support oligodendrocyte development and myelin formation
No differences were observed in fasting glucose/insulin (show INS Antibodies) levels, glucose tolerance, insulin (show INS Antibodies) sensitivity, or insulin (show INS Antibodies) secretion in comparing young or older males on in comparing insulin (show INS Antibodies) secretion from islets of wild type or activin B (show Actbeta Antibodies) knockout males.
There is a dramatic induction of Inhbb mRNA, e (show HAMP Antibodies)ncoding the activin beta(B)-subunit, in liver challenged with lipopolysaccharide, slight (show Actbeta Antibodies)ly preceding an increase in Smad1/5/8 phosphorylation and Hamp m (show HAMP Antibodies)RNA.
the transition between stem cells and committed progenitors is neither sharp nor irreversible and GDF11 (show GDF11 Antibodies), ACTbetaB and FST (show FST Antibodies) are crucial components of a circuit that controls both total cell number and the ratio of neuronal versus glial cells in this system
Presence of varicocele was associated with lower serum inhibin B.
Elevated activin B (show Actbeta Antibodies) levels together with normal activin A (show INHBA Antibodies) levels identified patients with the diagnostic symptoms of chronic fatigue syndrome/myalgic encephalomyelitis.
Results identified Inhbb as one factor mediating the proliferative effect of Pdx-1 (show PDX1 Antibodies) on islet cells.
Low activin B (show Actbeta Antibodies) level is associated with tubal ectopic pregnancy.
The Sertoli cell hormones inhibin-B and anti Mullerian hormone (show AMH Antibodies) have different patterns of secretion in prepubertal cryptorchid boys.
Pregnant Han Chinese women carrying the rs7579169 CC genotype and G-G-C haplotype are significantly more likely to develop pre-eclampsia, especially late-onset and multiparous cases.
We report here an original observation that activin-B (show Actbeta Antibodies) is upregulated in the human idiopathic pulmonary fibrosis lung.
reduction of RhoA (show RHOA Antibodies) signaling by Activin B (show Actbeta Antibodies) together with persistent Rac1 activity is a prerequisite for inducing an invasive phenotype in clear cell renal cell carcinoma (show MOK Antibodies).
inhibin B and anti-Mullerian hormone (show AMH Antibodies) serum concentrations did not provide an additional diagnostic tool for male infertility
Activin-A (show INHBA Antibodies) and -B are abundantly expressed in mesothelioma tumor tissue.
An increased expression of Inhibin-beta B was found in oocytes collected from large and medium follicles compared with small follicles before or after in oocyte vitro maturation.
our data indicate that miR (show MYLIP Antibodies)-34a plays an important role in granulosa cell apoptosis by targeting the INHBB gene in the porcine ovary
results indicated that boar testis produces inhibin A and inhibin B during the infantile period but inhibin A is the predominant form towards puberty and molecular weight forms of inhibin and the sites of production change with testicular development
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
activin beta B
, activin B
, activin beta B subunit
, inhibin, beta B
, inhibin beta B
, inhibin, beta B (activin AB beta polypeptide)
, inhibin beta B chain-like
, activin beta-B chain
, activin betaB
, inhibin beta B chain
, inhibin beta subunit B
, Inhibin, beta-2
, activin AB beta polypeptide
, inhibin beta-(b) subunit
, betaB inhibin/activin
, inhibin beta B subunit