Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1) Peptide
SUB1
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all SUB1 products
- SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PC4 antibody (Catalog #: P100959_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
- Background
-
PC4 is a transcriptional coactivator. General transcription factor IIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity rather than by reducing the repressive activity of PC4 via its phosphorylation
Alias Symbols: P15, PC4, p14
Protein Interaction Partner: CSTF2,IRF1,TERF2,ADAP1,CSNK2A1,CSTF2,EP300,GTF2A1L,HNF4A,HSF1,PCNA,POU2AF1,SUB1,TAF1,TBP,CSTF2,EP300,HNF4A,POU2AF1,PSIP1,SP1,SUB1,SUB1
Protein Size: 127 - Molecular Weight
- 14 kDa
- Gene ID
- 10923
- NCBI Accession
- NM_006713, NP_006704
- UniProt
- P53999
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