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SUB1 Products

(Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))

Categories

expressed in 12 day embryo and in a chemically induced pancreatic B-cell tumor; not expressed in normal differentiated cells

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Featured SUB1 Categories

SUB1 Antibodies

High quality antibodies with extensive validation data.

SUB1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended SUB1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN6148686
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (3)
Cat. No. ABIN7261886
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN524333
Quantity 100 μg
Datasheet Datasheet

Recommended SUB1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970443
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1113254
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN511488
Quantity 96 tests
Datasheet Datasheet

Recommended SUB1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121666
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321837
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321832
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our SUB1 products

Luo, Zhang, Liao, Chen, Liu, Long, Jiang, Wang, Wang, Liu, Miao, Shi: "Transcriptional positive cofactor 4 promotes breast cancer proliferation and metastasis through c-Myc mediated Warburg effect." in: Cell communication and signaling : CCS, Vol. 17, Issue 1, pp. 36, (2019) (PubMed).

Chakravarthi, Goswami, Pathi, Robinson, Cieślik, Chandrashekar, Agarwal, Siddiqui, Daignault, Carskadon, Jing, Chinnaiyan, Kunju, Palanisamy, Varambally: "MicroRNA-101 regulated transcriptional modulator SUB1 plays a role in prostate cancer." in: Oncogene, (2016) (PubMed).

Mortusewicz, Evers, Helleday: "PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites." in: Oncogene, (2015) (PubMed).

Lin, Chang, Hsu, Chi, Chien, Liang, Tsai, Lin, Yu: "Low-molecular-mass secretome profiling identifies C-C motif chemokine 5 as a potential plasma biomarker and therapeutic target for nasopharyngeal carcinoma." in: Journal of proteomics, Vol. 94, pp. 186-201, (2013) (PubMed).

Das, Gadad, Kundu: "Human positive coactivator 4 controls heterochromatinization and silencing of neural gene expression by interacting with REST/NRSF and CoREST." in: Journal of molecular biology, Vol. 397, Issue 1, pp. 1-12, (2010) (PubMed).

Rajagopalan, Andreeva, Teufel, Freund, Fersht: "Interaction between the transactivation domain of p53 and PC4 exemplifies acidic activation domains as single-stranded DNA mimics." in: The Journal of biological chemistry, Vol. 284, Issue 32, pp. 21728-37, (2009) (PubMed).

Mortusewicz, Roth, Li, Cardoso, Meisterernst, Leonhardt: "Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites." in: The Journal of cell biology, Vol. 183, Issue 5, pp. 769-76, (2008) (PubMed).

Batta, Kundu: "Activation of p53 function by human transcriptional coactivator PC4: role of protein-protein interaction, DNA bending, and posttranslational modifications." in: Molecular and cellular biology, Vol. 27, Issue 21, pp. 7603-14, (2007) (PubMed).

Synonyms and alternative names related to SUB1

SUB1 homolog, transcriptional regulator (SUB1), SUB1 homolog (S. cerevisiae) (Sub1), SUB1 homolog, transcriptional regulator (Sub1), AI842364, P9, p14, P15, PC4, Pc4, Rpo2tc1

Protein level used designations for SUB1

  • activated RNA polymerase II transcription cofactor 4
  • activated RNA polymerase II transcriptional coactivator p15
  • positive cofactor 4
  • RNA polymerase II transcriptional coactivator
  • p14
  • single-stranded DNA-binding protein p9
  • PC4
  • pR-ET2 encoded oncodevelopmental protein
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